Joe Mixon is poised to be a significant contributor for the Houston Texans in the 2025 season. Despite recent foot and ankle issues, he is expected to be ready for training camp. Mixon's 2025 projections include 909.6 rushing yards and 9.6 rushing touchdowns, alongside 38.9 receptions for 327 receiving yards and 2.2 receiving touchdowns.

The Texans' run-heavy strategy, led by QB C.J. Stroud, positions Mixon as a central offensive figure. His high usage and red-zone opportunities make him a valuable fantasy asset, projected to score 192.9 fantasy points. Mixon's role as the primary back, with Woody Marks as his closest competition, ensures substantial volume.

In fantasy drafts, Mixon is ranked as RB29 with an ADP of #47, offering RB2 value with RB1 upside. Dynasty managers might consider selling high if Mixon performs well early, given his age and contract situation. Monitor his health closely during training camp to ensure no setbacks.