James Cook's recent signing of a four-year, $48 million extension with the Buffalo Bills, including $30 million guaranteed, solidifies his role as the team's lead running back through 2029. This move is pivotal for the Bills' 2025 Super Bowl aspirations, ensuring continuity in their offensive strategy.

Cook is projected to exceed 1,100 rushing yards and score 12–15 rushing touchdowns in 2025. His versatility is further highlighted by expected contributions of 35–45 receptions for 250–350 receiving yards and 2–4 receiving touchdowns. These projections underscore his importance in both the ground and aerial attack.

The Bills' 2025 outlook is strengthened by their robust offensive line and the presence of key players like Josh Allen and Keon Coleman. However, with Khalil Shakir recovering from injury, Cook's role becomes even more critical in maintaining offensive consistency. His chemistry with Allen is vital, especially given the wide receiver uncertainties.

Cook's red zone efficiency, as demonstrated by his franchise record for touchdowns in 2024, is crucial for the Bills' scoring potential. His extension removes any uncertainty at running back, positioning the Bills as a top-tier AFC contender. This stability in the backfield is essential for their balanced attack, making them a formidable opponent in the 2025 season.