The suspension of Demarcus Robinson for the first three games of the 2025 NFL season significantly impacts the San Francisco 49ers' wide receiver depth. With Brandon Aiyuk sidelined due to an ACL injury, the team will rely heavily on Ricky Pearsall and Jauan Jennings, though Jennings is also managing a calf injury.

Ricky Pearsall, who recorded 31 receptions for 400 yards and 3 touchdowns as a rookie, is projected to be the WR1 during Robinson's absence. His strong camp performance positions him as a key fantasy target in early 2025. Skyy Moore, recently acquired from Kansas City, may see increased snaps and could be a valuable waiver wire pickup, especially in deeper leagues.

Fantasy managers should monitor Jacob Cowing's hamstring recovery, as his return could alter target distribution. Robinson's projected 13.9 receptions, 217.8 yards, and 1.9 touchdowns for the season suggest limited fantasy value, making him a potential trade candidate once active.