| 1 | Trey McBrideArizona Cardinals·#85 | 14 | 100 | 75 | 760 | 8 | 75.0% | 7.60 | 10.13 | 341 | 688 | 1.6 | 24 | 14 | 8 | 77 | 259 | 78 | 18 | 37 | 3 | 443 |
| 2 | Colston LovelandChicago Bears·#84 | 12 | 47 | 35 | 432 | 6 | 74.5% | 9.19 | 12.34 | 140 | 362 | 1.7 | 9 | 7 | 4 | 35 | 140 | 40 | 6 | 23 | 0 | 231 |
| 3 | Brock BowersLas Vegas Raiders·#89 | 12 | 67 | 50 | 453 | 6 | 74.6% | 6.76 | 9.06 | 209 | 311 | 1.2 | 15 | 8 | 5 | 34 | 201 | 60 | 7 | 27 | 1 | 315 |
| 4 | AJ BarnerSeattle Seahawks·#88 | 10 | 32 | 28 | 237 | 5 | 87.5% | 7.41 | 8.46 | 102 | 151 | 0.9 | 7 | 7 | 4 | 12 | 106 | 27 | 7 | 15 | 2 | 156 |
| 5 | Hunter HenryNew England Patriots·#85 | 13 | 33 | 23 | 252 | 4 | 69.7% | 7.64 | 10.96 | 103 | 185 | 1.5 | 7 | 5 | 3 | 16 | 111 | 25 | 7 | 16 | 0 | 175 |
| 6 | Jake TongesSan Francisco 49ers·#88 | 8 | 23 | 19 | 188 | 4 | 82.6% | 8.17 | 9.89 | 88 | 152 | 1.4 | 4 | 4 | 3 | 16 | 78 | 14 | 6 | 12 | 1 | 109 |
| 7 | Kyle PittsAtlanta Falcons·#8 | 11 | 58 | 46 | 487 | 4 | 79.3% | 8.40 | 10.59 | 213 | 409 | 1.5 | 7 | 4 | 4 | 39 | 169 | 39 | 9 | 27 | 2 | 265 |
| 8 | Dallas GoedertPhiladelphia Eagles·#88 | 7 | 33 | 25 | 290 | 3 | 75.8% | 8.79 | 11.60 | 88 | 227 | 1.7 | 4 | 4 | 2 | 16 | 106 | 23 | 5 | 14 | 3 | 168 |
| 9 | David NjokuCleveland Browns·#85 | 11 | 33 | 22 | 194 | 3 | 66.7% | 5.88 | 8.82 | 88 | 205 | 0.9 | 7 | 5 | 3 | 30 | 136 | 24 | 7 | 8 | 2 | 216 |
| 10 | Darren WallerMiami Dolphins·#83 | 6 | 13 | 9 | 81 | 3 | 69.2% | 6.23 | 9.00 | 11 | 101 | 1.5 | 4 | 3 | 3 | 8 | 40 | 12 | 2 | 6 | 0 | 66 |
| 11 | Dawson KnoxBuffalo Bills·#88 | 12 | 28 | 22 | 230 | 3 | 78.6% | 8.21 | 10.45 | 101 | 131 | 0.8 | 9 | 5 | 3 | 25 | 119 | 21 | 5 | 13 | 1 | 202 |
| 12 | Harold Fannin Jr.Cleveland Browns·#44 | 13 | 77 | 51 | 529 | 3 | 66.2% | 6.87 | 10.37 | 235 | 500 | 1.6 | 9 | 5 | 2 | 37 | 188 | 56 | 9 | 21 | 3 | 330 |
| 13 | Pat FreiermuthPittsburgh Steelers·#88 | 13 | 31 | 25 | 354 | 3 | 80.7% | 11.42 | 14.16 | 149 | 211 | 1.2 | 4 | 3 | 2 | 31 | 112 | 25 | 6 | 16 | 1 | 189 |
| 14 | Dalton KincaidBuffalo Bills·#86 | 7 | 23 | 19 | 294 | 2 | 82.6% | 12.78 | 15.47 | 142 | 188 | 2.1 | 5 | 4 | 2 | 15 | 66 | 18 | 3 | 15 | 0 | 97 |
| 15 | Gunnar HelmTennessee Titans·#84 | 16 | 40 | 34 | 278 | 2 | 85.0% | 6.95 | 8.18 | 110 | 189 | 1.0 | 6 | 4 | 1 | 20 | 110 | 25 | 4 | 13 | 2 | 200 |
| 16 | Davis AllenLos Angeles Rams·#87 | 11 | 15 | 10 | 92 | 2 | 66.7% | 6.13 | 9.20 | 49 | 59 | 0.6 | 4 | 3 | 2 | 7 | 68 | 10 | 3 | 7 | 1 | 92 |
| 17 | Colby ParkinsonLos Angeles Rams·#84 | 10 | 22 | 18 | 189 | 2 | 81.8% | 8.59 | 10.50 | 112 | 121 | 1.1 | 6 | 3 | 0 | 15 | 86 | 13 | 3 | 9 | 0 | 120 |
| 18 | Zach ErtzWashington Commanders·#86 | 11 | 53 | 36 | 394 | 2 | 67.9% | 7.43 | 10.94 | 102 | 491 | 1.6 | 6 | 4 | 2 | 40 | 151 | 44 | 8 | 19 | 1 | 300 |
| 19 | George KittleSan Francisco 49ers·#85 | 7 | 25 | 21 | 219 | 2 | 84.0% | 8.76 | 10.43 | 63 | 168 | 1.5 | 5 | 5 | 2 | 23 | 86 | 21 | 3 | 11 | 1 | 122 |
| 20 | Oronde Gadsden IILos Angeles Chargers·#86 | 13 | 39 | 25 | 379 | 2 | 64.1% | 9.72 | 15.16 | 126 | 331 | 1.5 | 11 | 4 | 2 | 31 | 157 | 33 | 5 | 14 | 1 | 247 |
| 21 | Mark AndrewsBaltimore Ravens·#89 | 14 | 29 | 21 | 194 | 2 | 72.4% | 6.69 | 9.24 | 54 | 207 | 1.1 | 6 | 1 | 1 | 22 | 107 | 22 | 7 | 11 | 5 | 183 |
| 22 | Terrance FergusonLos Angeles Rams·#18 | 7 | 9 | 5 | 84 | 2 | 55.6% | 9.33 | 16.80 | 5 | 133 | 1.9 | 2 | 1 | 1 | 8 | 52 | 8 | 3 | 4 | 1 | 72 |
| 23 | Tucker KraftGreen Bay Packers·#85 | 4 | 19 | 12 | 174 | 2 | 63.2% | 9.16 | 14.50 | 131 | 53 | 0.8 | 7 | 5 | 2 | 8 | 55 | 13 | 0 | 8 | 0 | 81 |
| 24 | Travis KelceKansas City Chiefs·#87 | 14 | 60 | 43 | 485 | 2 | 71.7% | 8.08 | 11.28 | 227 | 387 | 1.2 | 9 | 5 | 0 | 21 | 185 | 48 | 4 | 26 | 0 | 345 |
| 25 | Mitchell EvansCarolina Panthers·#84 | 14 | 14 | 10 | 78 | 2 | 71.4% | 5.57 | 7.80 | 46 | 42 | 0.5 | 3 | 2 | 2 | 5 | 56 | 9 | 1 | 4 | 1 | 88 |
| 26 | Juwan JohnsonNew Orleans Saints·#83 | 17 | 83 | 62 | 688 | 2 | 74.7% | 8.29 | 11.10 | 286 | 479 | 1.4 | 7 | 5 | 2 | 57 | 291 | 71 | 19 | 33 | 4 | 463 |
| 27 | Tyler WarrenIndianapolis Colts·#84 | 12 | 48 | 29 | 339 | 2 | 60.4% | 7.06 | 11.69 | 160 | 266 | 1.3 | 11 | 5 | 2 | 40 | 151 | 40 | 11 | 18 | 5 | 245 |
| 28 | Austin HooperNew England Patriots·#81 | 10 | 9 | 6 | 85 | 1 | 66.7% | 9.44 | 14.17 | 24 | 99 | 1.4 | 2 | 2 | 1 | 6 | 42 | 8 | 3 | 4 | 0 | 72 |
| 29 | Dalton SchultzHouston Texans·#86 | 11 | 42 | 29 | 243 | 1 | 69.0% | 5.79 | 8.38 | 118 | 205 | 1.3 | 4 | 1 | 1 | 20 | 120 | 36 | 6 | 13 | 1 | 194 |
| 30 | Brenton StrangeJacksonville Jaguars·#85 | 8 | 12 | 10 | 165 | 1 | 83.3% | 13.75 | 16.50 | 92 | 110 | 1.8 | 3 | 2 | 1 | 7 | 38 | 10 | 0 | 9 | 0 | 63 |
| 31 | Chig OkonkwoTennessee Titans·#85 | 17 | 53 | 37 | 378 | 1 | 69.8% | 7.13 | 10.22 | 210 | 241 | 0.9 | 3 | 2 | 1 | 31 | 183 | 36 | 5 | 16 | 6 | 331 |
| 32 | Ben SinnottWashington Commanders·#82 | 13 | 11 | 10 | 78 | 1 | 90.9% | 7.09 | 7.80 | 49 | 59 | 0.7 | 1 | 1 | 1 | 8 | 45 | 6 | 0 | 4 | 1 | 80 |
| 33 | Brevyn Spann-FordDallas Cowboys·#89 | 14 | 5 | 3 | 18 | 1 | 60.0% | 3.60 | 6.00 | 0 | 18 | 1.2 | 1 | 1 | 1 | 7 | 28 | 4 | 1 | 2 | 0 | 46 |
| 34 | Tommy TrembleCarolina Panthers·#82 | 14 | 20 | 15 | 111 | 1 | 75.0% | 5.55 | 7.40 | 45 | 106 | 0.5 | 3 | 2 | 1 | 18 | 130 | 17 | 3 | 4 | 3 | 205 |
| 35 | Noah FantCincinnati Bengals·#86 | 14 | 25 | 22 | 162 | 1 | 88.0% | 6.48 | 7.36 | 80 | 86 | 0.7 | 0 | 0 | 0 | 20 | 93 | 12 | 4 | 5 | 4 | 133 |
| 36 | Mo Alie-CoxIndianapolis Colts·#81 | 11 | 9 | 6 | 41 | 1 | 66.7% | 4.56 | 6.83 | 27 | 36 | 0.5 | 4 | 4 | 1 | 8 | 49 | 5 | 4 | 1 | 0 | 77 |
| 37 | Mason TaylorNew York Jets·#85 | 12 | 52 | 35 | 306 | 1 | 67.3% | 5.88 | 8.74 | 118 | 281 | 1.0 | 9 | 7 | 1 | 45 | 165 | 43 | 6 | 21 | 3 | 299 |
| 38 | Tanner HudsonCincinnati Bengals·#87 | 9 | 16 | 13 | 99 | 1 | 81.3% | 6.19 | 7.62 | 44 | 70 | 0.9 | 3 | 2 | 1 | 14 | 44 | 14 | 3 | 3 | 0 | 74 |
| 39 | Sam LaPortaDetroit Lions·#87 | 5 | 21 | 15 | 166 | 1 | 71.4% | 7.90 | 11.07 | 79 | 125 | 1.2 | 3 | 1 | 1 | 9 | 73 | 14 | 3 | 7 | 0 | 104 |
| 40 | John BatesWashington Commanders·#87 | 13 | 11 | 8 | 53 | 1 | 72.7% | 4.82 | 6.62 | 42 | 10 | 0.1 | 2 | 1 | 1 | 15 | 76 | 8 | 1 | 4 | 0 | 133 |
| 41 | Isaiah LikelyBaltimore Ravens·#80 | 12 | 21 | 15 | 143 | 1 | 71.4% | 6.81 | 9.53 | 34 | 160 | 1.2 | 4 | 1 | 1 | 17 | 80 | 15 | 5 | 6 | 1 | 136 |
| 42 | Jackson HawesBuffalo Bills·#85 | 13 | 6 | 5 | 100 | 1 | 83.3% | 16.67 | 20.00 | 34 | 93 | 1.4 | 0 | 0 | 0 | 5 | 40 | 3 | 1 | 5 | 0 | 69 |
| 43 | Jeremy RuckertNew York Jets·#89 | 16 | 23 | 17 | 130 | 1 | 73.9% | 5.65 | 7.65 | 73 | 68 | 0.4 | 3 | 1 | 1 | 25 | 118 | 17 | 5 | 7 | 2 | 193 |
| 44 | Jonnu SmithPittsburgh Steelers·#81 | 14 | 28 | 21 | 110 | 1 | 75.0% | 3.93 | 5.24 | 95 | 48 | 0.6 | 7 | 4 | 1 | 29 | 98 | 16 | 7 | 4 | 1 | 169 |
| 45 | Josh OliverMinnesota Vikings·#84 | 9 | 7 | 4 | 48 | 1 | 57.1% | 6.86 | 12.00 | 29 | 16 | 0.3 | 4 | 2 | 0 | 6 | 33 | 6 | 1 | 1 | 0 | 59 |
| 46 | Jake FergusonDallas Cowboys·#87 | 16 | 64 | 51 | 401 | 1 | 79.7% | 6.27 | 7.86 | 175 | 299 | 1.0 | 11 | 5 | 1 | 47 | 236 | 48 | 13 | 21 | 3 | 342 |
| 47 | Ja'Tavion SandersCarolina Panthers·#0 | 10 | 25 | 22 | 163 | 1 | 88.0% | 6.52 | 7.41 | 73 | 111 | 0.8 | 7 | 6 | 1 | 24 | 102 | 18 | 3 | 7 | 2 | 157 |
| 48 | Daniel BellingerNew York Giants·#82 | 13 | 13 | 10 | 134 | 1 | 76.9% | 10.31 | 13.40 | 80 | 81 | 1.0 | 2 | 2 | 0 | 17 | 47 | 11 | 5 | 8 | 1 | 86 |
| 49 | Darnell WashingtonPittsburgh Steelers·#80 | 12 | 15 | 9 | 84 | 1 | 60.0% | 5.60 | 9.33 | 55 | 81 | 1.1 | 5 | 3 | 1 | 13 | 58 | 10 | 1 | 5 | 1 | 89 |
| 50 | Drew SampleCincinnati Bengals·#89 | 15 | 15 | 10 | 73 | 1 | 66.7% | 4.87 | 7.30 | 69 | 0 | 0.0 | 1 | 1 | 1 | 27 | 119 | 1 | 7 | 4 | 1 | 178 |