| 1 | Ameer AbdullahIndianapolis Colts·#26 | 13 | 13 | 60 | 4.62 | 1 | 32 | 3 | 1 | 17 | 16 | 99 | 0 | 94.1% | 5.82 | 6.19 | 105 | 1 | 1 | 0 | 0 | 77 |
| 2 | Austin EkelerWashington Commanders·#30 | 2 | 14 | 43 | 3.07 | 0 | 40 | 3 | 0 | 7 | 5 | 38 | 0 | 71.4% | 5.43 | 7.60 | 49 | 0 | 0 | 0 | 0 | 67 |
| 3 | Brian RobinsonSan Francisco 49ers·#3 | 17 | 92 | 400 | 4.35 | 2 | 226 | 21 | 2 | 12 | 8 | 25 | 0 | 66.7% | 2.08 | 3.12 | 35 | 4 | 3 | 0 | 0 | 165 |
| 4 | Chris BrooksGreen Bay Packers·#30 | 17 | 27 | 106 | 3.93 | 0 | 87 | 5 | 0 | 17 | 13 | 91 | 0 | 76.5% | 5.35 | 7.00 | 106 | 3 | 1 | 0 | 0 | 172 |
| 5 | D'Ernest JohnsonNew England Patriots·#34 | 5 | 13 | 25 | 1.92 | 0 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | — | — | — | 0 | 0 | 0 | 0 | 0 | 25 |
| 6 | Devin NealNew Orleans Saints·#24 | 9 | 57 | 206 | 3.61 | 2 | 103 | 11 | 2 | 19 | 17 | 104 | 0 | 89.5% | 5.47 | 6.12 | 138 | 1 | 1 | 0 | 0 | 239 |
| 7 | Corey KinerArizona Cardinals·#37 | 4 | 12 | 58 | 4.83 | 0 | 26 | 4 | 0 | 3 | 2 | 15 | 0 | 66.7% | 5.00 | 7.50 | 6 | 1 | 1 | 0 | 0 | 27 |
| 8 | Dylan LaubeLas Vegas Raiders·#23 | 5 | 7 | 9 | 1.29 | 0 | 10 | 0 | 0 | 4 | 3 | 18 | 0 | 75.0% | 4.50 | 6.00 | 24 | 0 | 0 | 0 | 0 | 26 |
| 9 | Jaydon BlueDallas Cowboys·#23 | 5 | 38 | 129 | 3.39 | 1 | 54 | 7 | 1 | 1 | 1 | 5 | 0 | 100.0% | 5.00 | 5.00 | 10 | 0 | 0 | 0 | 0 | 71 |
| 10 | Jawhar JordanHouston Texans·#26 | 4 | 43 | 193 | 4.49 | 0 | 129 | 8 | 1 | 7 | 7 | 34 | 0 | 100.0% | 4.86 | 4.86 | 40 | 0 | 0 | 0 | 0 | 74 |
| 11 | Kaleb JohnsonPittsburgh Steelers·#20 | 10 | 28 | 69 | 2.46 | 0 | 44 | 3 | 0 | 2 | 1 | 9 | 0 | 50.0% | 4.50 | 9.00 | 14 | 0 | 0 | 0 | 0 | 46 |
| 12 | Julius ChestnutTennessee Titans·#36 | 9 | 11 | 40 | 3.64 | 0 | 17 | 4 | 2 | 2 | 0 | 0 | 0 | 0.0% | 0.00 | — | 0 | 0 | 0 | 0 | 0 | 35 |
| 13 | Isiah PachecoKansas City Chiefs·#10 | 13 | 118 | 462 | 3.92 | 1 | 291 | 27 | 0 | 26 | 19 | 101 | 1 | 73.1% | 3.88 | 5.32 | 121 | 4 | 2 | 1 | 0 | 391 |
| 14 | James ConnerArizona Cardinals·#6 | 3 | 32 | 95 | 2.97 | 1 | 98 | 7 | 3 | 9 | 8 | 38 | 1 | 88.9% | 4.22 | 4.75 | 68 | 1 | 1 | 1 | 0 | 85 |
| 15 | Emanuel WilsonGreen Bay Packers·#23 | 17 | 125 | 496 | 3.97 | 3 | 397 | 32 | 4 | 18 | 15 | 101 | 0 | 83.3% | 5.61 | 6.73 | 133 | 3 | 1 | 0 | 0 | 300 |
| 16 | Woody MarksHouston Texans·#27 | 16 | 196 | 703 | 3.59 | 2 | 475 | 41 | 9 | 36 | 24 | 208 | 3 | 66.7% | 5.78 | 8.67 | 223 | 8 | 5 | 3 | 0 | 528 |
| 17 | Trayveon WilliamsCleveland Browns·#38 | 4 | 7 | 37 | 5.29 | 0 | 34 | 3 | 0 | 8 | 7 | 55 | 0 | 87.5% | 6.88 | 7.86 | 82 | 2 | 2 | 0 | 0 | 60 |
| 18 | Trevor EtienneCarolina Panthers·#23 | 11 | 20 | 94 | 4.70 | 0 | 55 | 7 | 1 | 3 | 3 | 13 | 0 | 100.0% | 4.33 | 4.33 | 11 | 0 | 0 | 0 | 0 | 42 |
| 19 | Ty ChandlerMinnesota Vikings·#32 | 2 | 17 | 47 | 2.76 | 0 | 36 | 1 | 1 | 4 | 3 | 11 | 0 | 75.0% | 2.75 | 3.67 | 27 | 2 | 1 | 0 | 0 | 34 |
| 20 | Tyler BadieDenver Broncos·#28 | 16 | 8 | 23 | 2.88 | 0 | 53 | 1 | 1 | 31 | 19 | 141 | 0 | 61.3% | 4.55 | 7.42 | 210 | 4 | 3 | 0 | 0 | 175 |
| 21 | Will ShipleyPhiladelphia Eagles·#28 | 15 | 13 | 45 | 3.46 | 0 | 18 | 4 | 0 | 12 | 9 | 56 | 0 | 75.0% | 4.67 | 6.22 | 63 | 1 | 0 | 0 | 0 | 101 |
| 22 | Tank BigsbyPhiladelphia Eagles·#37 | 11 | 55 | 306 | 5.56 | 1 | 219 | 16 | 6 | 4 | 3 | 32 | 0 | 75.0% | 8.00 | 10.67 | 39 | 1 | 1 | 0 | 0 | 114 |
| 23 | Tahj BrooksCincinnati Bengals·#25 | 8 | 16 | 45 | 2.81 | 0 | 29 | 1 | 0 | 2 | 1 | 9 | 0 | 50.0% | 4.50 | 9.00 | 11 | 0 | 0 | 0 | 0 | 40 |
| 24 | Sean TuckerTampa Bay Buccaneers·#44 | 15 | 85 | 320 | 3.76 | 7 | 173 | 22 | 11 | 11 | 8 | 34 | 1 | 72.7% | 3.09 | 4.25 | 49 | 3 | 1 | 0 | 0 | 163 |
| 25 | Ray DavisBuffalo Bills·#22 | 17 | 58 | 275 | 4.74 | 0 | 171 | 15 | 2 | 14 | 10 | 86 | 2 | 71.4% | 6.14 | 8.60 | 99 | 5 | 4 | 2 | 0 | 135 |
| 26 | Raheim SandersCleveland Browns·#35 | 4 | 27 | 92 | 3.41 | 1 | 78 | 7 | 4 | 4 | 3 | 21 | 0 | 75.0% | 5.25 | 7.00 | 14 | 0 | 0 | 0 | 0 | 51 |
| 27 | Terrell JenningsNew England Patriots·#26 | 5 | 23 | 73 | 3.17 | 1 | 36 | 8 | 2 | 1 | 1 | 9 | 0 | 100.0% | 9.00 | 9.00 | 7 | 0 | 0 | 0 | 0 | 30 |
| 28 | Najee HarrisLos Angeles Chargers·#22 | 3 | 15 | 61 | 4.07 | 0 | 45 | 3 | 0 | 3 | 3 | 25 | 0 | 100.0% | 8.33 | 8.33 | 15 | 0 | 0 | 0 | 0 | 39 |
| 29 | Khalil HerbertNew York Jets·#31 | 3 | 16 | 52 | 3.25 | 0 | 26 | 3 | 0 | 4 | 1 | 4 | 0 | 25.0% | 1.00 | 4.00 | 9 | 1 | 0 | 0 | 0 | 47 |
| 30 | Kimani VidalLos Angeles Chargers·#30 | 13 | 155 | 643 | 4.15 | 3 | 336 | 35 | 7 | 22 | 16 | 136 | 1 | 72.7% | 6.18 | 8.50 | 170 | 6 | 3 | 1 | 0 | 452 |
| 31 | Kyle MonangaiChicago Bears·#25 | 17 | 170 | 783 | 4.61 | 5 | 407 | 43 | 12 | 30 | 18 | 164 | 0 | 60.0% | 5.47 | 9.11 | 162 | 3 | 2 | 0 | 0 | 450 |
| 32 | Kene NwangwuNew York Jets·#34 | 3 | 13 | 49 | 3.77 | 0 | 25 | 2 | 2 | 1 | 0 | 0 | 0 | 0.0% | 0.00 | — | 0 | 0 | 0 | 0 | 0 | 27 |
| 33 | Zamir WhiteLas Vegas Raiders·#3 | 5 | 12 | 32 | 2.67 | 0 | 30 | 1 | 0 | 6 | 4 | 24 | 0 | 66.7% | 4.00 | 6.00 | 24 | 0 | 0 | 0 | 0 | 52 |
| 34 | Evan HullNew Orleans Saints·#34 | 6 | 18 | 47 | 2.61 | 0 | 19 | 2 | 0 | 1 | 1 | 6 | 0 | 100.0% | 6.00 | 6.00 | 10 | 0 | 0 | 0 | 1 | 66 |
| 35 | Jaylen WrightMiami Dolphins·#5 | 10 | 70 | 288 | 4.11 | 2 | 221 | 17 | 4 | 9 | 5 | 44 | 0 | 55.6% | 4.89 | 8.80 | 60 | 0 | 0 | 0 | 1 | 113 |
| 36 | Ollie Gordon IIMiami Dolphins·#31 | 17 | 70 | 199 | 2.84 | 3 | 114 | 21 | 6 | 9 | 7 | 32 | 1 | 77.8% | 3.56 | 4.57 | 57 | 2 | 2 | 1 | 1 | 193 |
| 37 | Nick ChubbHouston Texans·#21 | 15 | 122 | 506 | 4.15 | 3 | 341 | 20 | 6 | 20 | 13 | 67 | 0 | 65.0% | 3.35 | 5.15 | 63 | 2 | 1 | 0 | 1 | 297 |
| 38 | Quinshon JudkinsCleveland Browns·#10 | 14 | 231 | 829 | 3.59 | 7 | 537 | 51 | 12 | 36 | 26 | 171 | 0 | 72.2% | 4.75 | 6.58 | 194 | 1 | 1 | 0 | 1 | 425 |
| 39 | Kendre MillerNew Orleans Saints·#5 | 7 | 47 | 193 | 4.11 | 1 | 156 | 9 | 0 | 5 | 5 | 30 | 0 | 100.0% | 6.00 | 6.00 | 35 | 0 | 0 | 0 | 1 | 102 |
| 40 | Travis EtienneJacksonville Jaguars·#1 | 17 | 259 | 1,109 | 4.28 | 7 | 739 | 51 | 12 | 52 | 36 | 292 | 6 | 69.2% | 5.62 | 8.11 | 339 | 10 | 8 | 5 | 1 | 639 |
| 41 | Tyler GoodsonIndianapolis Colts·#31 | 8 | 9 | 24 | 2.67 | 0 | 6 | 0 | 0 | 3 | 2 | 8 | 0 | 66.7% | 2.67 | 4.00 | 10 | 1 | 0 | 0 | 1 | 33 |
| 42 | Ty JohnsonBuffalo Bills·#26 | 17 | 49 | 200 | 4.08 | 3 | 158 | 13 | 6 | 33 | 24 | 231 | 2 | 72.7% | 7.00 | 9.62 | 269 | 4 | 2 | 1 | 1 | 299 |
| 43 | Trey BensonArizona Cardinals·#33 | 4 | 29 | 160 | 5.52 | 0 | 157 | 4 | 1 | 16 | 13 | 64 | 0 | 81.3% | 4.00 | 4.92 | 73 | 2 | 1 | 0 | 1 | 113 |
| 44 | Zavier ScottMinnesota Vikings·#36 | 9 | 32 | 114 | 3.56 | 0 | 78 | 6 | 1 | 15 | 14 | 98 | 1 | 93.3% | 6.53 | 7.00 | 105 | 3 | 3 | 1 | 1 | 97 |
| 45 | RJ HarveyDenver Broncos·#12 | 17 | 147 | 540 | 3.67 | 7 | 395 | 30 | 10 | 58 | 47 | 356 | 5 | 81.0% | 6.14 | 7.57 | 360 | 11 | 9 | 4 | 1 | 448 |
| 46 | Raheem MostertLas Vegas Raiders·#31 | 12 | 21 | 100 | 4.76 | 0 | 84 | 5 | 0 | 12 | 12 | 70 | 0 | 100.0% | 5.83 | 5.83 | 86 | 1 | 1 | 0 | 1 | 119 |
| 47 | Michael CarterArizona Cardinals·#22 | 13 | 92 | 333 | 3.62 | 1 | 257 | 20 | 3 | 45 | 33 | 267 | 0 | 73.3% | 5.93 | 8.09 | 257 | 7 | 4 | 0 | 1 | 374 |
| 48 | Antonio GibsonNew England Patriots·#4 | 5 | 25 | 106 | 4.24 | 1 | 62 | 6 | 2 | 3 | 2 | 6 | 0 | 66.7% | 2.00 | 3.00 | 16 | 0 | 0 | 0 | 1 | 46 |
| 49 | DJ GiddensIndianapolis Colts·#21 | 6 | 26 | 96 | 3.69 | 0 | 59 | 5 | 1 | 2 | 0 | 0 | 0 | 0.0% | 0.00 | — | 0 | 1 | 0 | 0 | 1 | 54 |
| 50 | Devin SingletaryNew York Giants·#26 | 17 | 119 | 437 | 3.67 | 5 | 274 | 28 | 10 | 19 | 18 | 151 | 0 | 94.7% | 7.95 | 8.39 | 162 | 2 | 2 | 0 | 1 | 279 |