| 1 | Trey McBrideArizona Cardinals·#85 | 17 | 124 | 87 | 922 | 10 | 70.2% | 7.44 | 10.60 | 285 | 1,017 | 8.6 | 27 | 17 | 10 | 33 | 95 | 124 | 5 | 53 | 0 | 124 |
| 2 | Juwan JohnsonNew Orleans Saints·#83 | 17 | 87 | 64 | 715 | 3 | 73.6% | 8.22 | 11.17 | 258 | 535 | 8.0 | 7 | 5 | 2 | 19 | 72 | 87 | 6 | 36 | 1 | 87 |
| 3 | Travis KelceKansas City Chiefs·#87 | 17 | 88 | 63 | 724 | 5 | 71.6% | 8.23 | 11.49 | 333 | 569 | 7.1 | 12 | 8 | 3 | 9 | 71 | 88 | 0 | 41 | 0 | 88 |
| 4 | Kyle PittsAtlanta Falcons·#8 | 17 | 82 | 60 | 726 | 5 | 73.2% | 8.85 | 12.10 | 252 | 741 | 9.2 | 10 | 6 | 5 | 16 | 65 | 82 | 1 | 44 | 0 | 82 |
| 5 | Dalton SchultzHouston Texans·#86 | 17 | 83 | 60 | 584 | 1 | 72.3% | 7.04 | 9.73 | 252 | 495 | 6.8 | 8 | 3 | 1 | 10 | 65 | 83 | 1 | 29 | 0 | 83 |
| 6 | Brock BowersLas Vegas Raiders·#89 | 12 | 77 | 59 | 645 | 7 | 76.6% | 8.38 | 10.93 | 271 | 439 | 6.7 | 16 | 10 | 6 | 15 | 63 | 77 | 4 | 34 | 0 | 77 |
| 7 | Tyler WarrenIndianapolis Colts·#84 | 17 | 88 | 55 | 633 | 4 | 62.5% | 7.19 | 11.51 | 299 | 518 | 6.7 | 21 | 9 | 4 | 15 | 61 | 88 | 1 | 33 | 0 | 88 |
| 8 | Jake FergusonDallas Cowboys·#87 | 16 | 70 | 53 | 427 | 7 | 75.7% | 6.10 | 8.06 | 149 | 362 | 5.9 | 21 | 12 | 7 | 13 | 57 | 70 | 3 | 26 | 0 | 70 |
| 9 | Harold Fannin Jr.Cleveland Browns·#44 | 16 | 76 | 48 | 546 | 6 | 63.2% | 7.18 | 11.38 | 208 | 549 | 7.2 | 10 | 6 | 4 | 16 | 54 | 76 | 3 | 26 | 0 | 76 |
| 10 | Colston LovelandChicago Bears·#84 | 15 | 70 | 48 | 591 | 5 | 68.6% | 8.44 | 12.31 | 223 | 537 | 8.7 | 15 | 10 | 4 | 14 | 50 | 70 | 3 | 32 | 0 | 70 |
| 11 | George KittleSan Francisco 49ers·#85 | 11 | 54 | 44 | 523 | 6 | 81.5% | 9.69 | 11.89 | 137 | 422 | 8.4 | 12 | 11 | 5 | 8 | 47 | 54 | 2 | 34 | 0 | 54 |
| 12 | Zach ErtzWashington Commanders·#86 | 13 | 61 | 44 | 435 | 4 | 72.1% | 7.13 | 9.89 | 100 | 517 | 8.5 | 8 | 5 | 4 | 8 | 53 | 61 | 0 | 23 | 0 | 61 |
| 13 | Hunter HenryNew England Patriots·#85 | 17 | 68 | 43 | 583 | 6 | 63.2% | 8.57 | 13.56 | 220 | 505 | 9.3 | 17 | 10 | 4 | 10 | 48 | 68 | 1 | 34 | 0 | 68 |
| 14 | Mark AndrewsBaltimore Ravens·#89 | 17 | 56 | 42 | 364 | 5 | 75.0% | 6.50 | 8.67 | 88 | 373 | 6.7 | 11 | 5 | 4 | 13 | 46 | 56 | 2 | 21 | 0 | 56 |
| 15 | Cade OttonTampa Bay Buccaneers·#88 | 15 | 57 | 41 | 414 | 1 | 71.9% | 7.26 | 10.10 | 196 | 313 | 6.1 | 6 | 3 | 1 | 9 | 45 | 57 | 1 | 19 | 0 | 57 |
| 16 | Oronde Gadsden IILos Angeles Chargers·#86 | 15 | 57 | 41 | 575 | 2 | 71.9% | 10.09 | 14.02 | 209 | 459 | 9.3 | 11 | 6 | 2 | 9 | 44 | 57 | 1 | 23 | 1 | 57 |
| 17 | AJ BarnerSeattle Seahawks·#88 | 16 | 50 | 40 | 402 | 6 | 80.0% | 8.04 | 10.05 | 180 | 267 | 5.3 | 12 | 10 | 5 | 3 | 42 | 50 | 0 | 22 | 0 | 50 |
| 18 | Dallas GoedertPhiladelphia Eagles·#88 | 15 | 56 | 40 | 431 | 6 | 71.4% | 7.70 | 10.78 | 140 | 372 | 8.0 | 9 | 7 | 5 | 3 | 42 | 56 | 0 | 23 | 0 | 56 |
| 19 | Mason TaylorNew York Jets·#85 | 12 | 52 | 36 | 322 | 0 | 69.2% | 6.19 | 8.94 | 116 | 301 | 6.2 | 7 | 5 | 0 | 12 | 43 | 52 | 3 | 21 | 0 | 52 |
| 20 | Brenton StrangeJacksonville Jaguars·#85 | 11 | 43 | 33 | 424 | 3 | 76.7% | 9.86 | 12.85 | 167 | 337 | 8.3 | 7 | 4 | 2 | 6 | 36 | 43 | 0 | 22 | 0 | 43 |
| 21 | Chig OkonkwoTennessee Titans·#85 | 17 | 47 | 33 | 381 | 1 | 70.2% | 8.11 | 11.55 | 143 | 326 | 8.6 | 2 | 1 | 0 | 5 | 37 | 47 | 0 | 16 | 0 | 47 |
| 22 | T.J. HockensonMinnesota Vikings·#87 | 14 | 40 | 30 | 286 | 2 | 75.0% | 7.15 | 9.53 | 101 | 272 | 6.8 | 6 | 4 | 2 | 7 | 33 | 40 | 0 | 17 | 0 | 40 |
| 23 | Theo JohnsonNew York Giants·#84 | 14 | 54 | 29 | 394 | 4 | 53.7% | 7.30 | 13.59 | 102 | 533 | 10.5 | 10 | 3 | 3 | 13 | 37 | 54 | 3 | 18 | 0 | 54 |
| 24 | Dalton KincaidBuffalo Bills·#86 | 12 | 37 | 28 | 457 | 5 | 75.7% | 12.35 | 16.32 | 165 | 395 | 11.8 | 6 | 5 | 3 | 8 | 31 | 37 | 0 | 23 | 0 | 37 |
| 25 | Dawson KnoxBuffalo Bills·#88 | 15 | 38 | 28 | 354 | 3 | 73.7% | 9.32 | 12.64 | 150 | 254 | 7.5 | 10 | 6 | 3 | 5 | 32 | 38 | 0 | 20 | 0 | 38 |
| 26 | Pat FreiermuthPittsburgh Steelers·#88 | 14 | 37 | 27 | 341 | 4 | 73.0% | 9.22 | 12.63 | 128 | 246 | 7.3 | 6 | 3 | 3 | 7 | 27 | 37 | 0 | 14 | 0 | 37 |
| 27 | Sam LaPortaDetroit Lions·#87 | 9 | 32 | 27 | 393 | 2 | 84.4% | 12.28 | 14.56 | 203 | 221 | 6.9 | 4 | 2 | 1 | 3 | 26 | 32 | 1 | 17 | 0 | 32 |
| 28 | Evan EngramDenver Broncos·#1 | 14 | 39 | 26 | 301 | 1 | 66.7% | 7.72 | 11.58 | 149 | 191 | 6.2 | 8 | 5 | 1 | 7 | 28 | 39 | 2 | 15 | 0 | 39 |
| 29 | Gunnar HelmTennessee Titans·#84 | 14 | 35 | 25 | 246 | 2 | 71.4% | 7.03 | 9.84 | 63 | 254 | 8.2 | 7 | 4 | 1 | 7 | 27 | 35 | 3 | 13 | 0 | 35 |
| 30 | Tucker KraftGreen Bay Packers·#85 | 8 | 32 | 24 | 407 | 5 | 75.0% | 12.72 | 16.96 | 264 | 184 | 5.8 | 7 | 6 | 4 | 2 | 28 | 32 | 0 | 16 | 0 | 32 |
| 31 | Cole KmetChicago Bears·#85 | 15 | 34 | 24 | 298 | 2 | 70.6% | 8.76 | 12.42 | 115 | 248 | 8.8 | 5 | 3 | 1 | 3 | 26 | 34 | 2 | 14 | 0 | 34 |
| 32 | Mike GesickiCincinnati Bengals·#88 | 12 | 36 | 23 | 252 | 1 | 63.9% | 7.00 | 10.96 | 54 | 269 | 9.1 | 7 | 2 | 1 | 11 | 25 | 36 | 1 | 17 | 0 | 36 |
| 33 | David NjokuCleveland Browns·#85 | 11 | 33 | 23 | 202 | 4 | 69.7% | 6.12 | 8.78 | 76 | 195 | 5.9 | 7 | 5 | 4 | 8 | 24 | 33 | 4 | 10 | 0 | 33 |
| 34 | Michael MayerLas Vegas Raiders·#87 | 10 | 32 | 23 | 221 | 1 | 71.9% | 6.91 | 9.61 | 105 | 165 | 5.8 | 6 | 5 | 1 | 4 | 24 | 32 | 2 | 15 | 0 | 32 |
| 35 | Colby ParkinsonLos Angeles Rams·#84 | 14 | 32 | 22 | 228 | 8 | 68.8% | 7.12 | 10.36 | 107 | 236 | 7.5 | 18 | 13 | 6 | 4 | 25 | 32 | 1 | 18 | 1 | 32 |
| 36 | Greg DulcichMiami Dolphins·#85 | 9 | 26 | 21 | 280 | 1 | 80.8% | 10.77 | 13.33 | 152 | 150 | 5.8 | 5 | 2 | 1 | 5 | 21 | 26 | 1 | 12 | 1 | 26 |
| 37 | Darnell WashingtonPittsburgh Steelers·#80 | 12 | 31 | 21 | 283 | 1 | 67.7% | 9.13 | 13.48 | 151 | 193 | 6.9 | 8 | 5 | 1 | 2 | 25 | 31 | 0 | 15 | 1 | 31 |
| 38 | Luke MusgraveGreen Bay Packers·#88 | 13 | 26 | 21 | 235 | 0 | 80.8% | 9.04 | 11.19 | 53 | 264 | 10.2 | 1 | 0 | 0 | 3 | 24 | 26 | 0 | 11 | 0 | 26 |
| 39 | Tommy TrembleCarolina Panthers·#82 | 13 | 31 | 21 | 214 | 2 | 67.7% | 6.90 | 10.19 | 140 | 113 | 4.9 | 5 | 4 | 2 | 1 | 24 | 31 | 1 | 9 | 0 | 31 |
| 40 | Darren WallerMiami Dolphins·#83 | 8 | 30 | 20 | 240 | 5 | 66.7% | 8.00 | 12.00 | 61 | 274 | 10.4 | 7 | 5 | 5 | 5 | 20 | 30 | 3 | 16 | 0 | 30 |
| 41 | Isaiah LikelyBaltimore Ravens·#80 | 11 | 25 | 19 | 192 | 1 | 76.0% | 7.68 | 10.11 | 70 | 185 | 7.4 | 4 | 2 | 1 | 3 | 21 | 25 | 1 | 7 | 1 | 25 |
| 42 | Jake TongesSan Francisco 49ers·#88 | 9 | 27 | 19 | 182 | 3 | 70.4% | 6.74 | 9.58 | 39 | 218 | 8.2 | 4 | 4 | 3 | 5 | 22 | 27 | 0 | 15 | 0 | 27 |
| 43 | Jonnu SmithPittsburgh Steelers·#81 | 16 | 31 | 18 | 113 | 0 | 58.1% | 3.65 | 6.28 | 52 | 168 | 7.7 | 4 | 1 | 0 | 8 | 21 | 31 | 0 | 4 | 0 | 31 |
| 44 | Tyler HigbeeLos Angeles Rams·#89 | 9 | 26 | 16 | 207 | 3 | 61.5% | 7.96 | 12.94 | 69 | 115 | 4.5 | 5 | 3 | 2 | 7 | 20 | 26 | 1 | 15 | 0 | 26 |
| 45 | Noah GrayKansas City Chiefs·#83 | 12 | 29 | 14 | 142 | 0 | 48.3% | 4.90 | 10.14 | 75 | 211 | 8.0 | 2 | 0 | 0 | 3 | 17 | 29 | 2 | 6 | 0 | 29 |