| 1 | Hunter HenryNew England Patriots·#85 | 17 | 16 | 11 | 112 | 3 | 68.8% | 7.00 | 10.18 | 38 | 102 | 1.7 | 8 | 4 | 3 | 6 | 41 | 13 | 3 | 11 | 1 | 62 |
| 2 | Colston LovelandChicago Bears·#84 | 14 | 13 | 10 | 143 | 2 | 76.9% | 11.00 | 14.30 | 60 | 101 | 2.4 | 4 | 2 | 2 | 5 | 25 | 11 | 0 | 10 | 0 | 45 |
| 3 | Trey McBrideArizona Cardinals·#85 | 17 | 11 | 10 | 57 | 4 | 90.9% | 5.18 | 5.70 | 10 | 48 | 0.8 | 6 | 5 | 4 | 7 | 40 | 8 | 5 | 10 | 0 | 64 |
| 4 | Dallas GoedertPhiladelphia Eagles·#88 | 14 | 13 | 10 | 95 | 5 | 76.9% | 7.31 | 9.50 | 33 | 92 | 2.5 | 5 | 5 | 5 | 0 | 23 | 9 | 0 | 10 | 1 | 42 |
| 5 | Dalton SchultzHouston Texans·#86 | 16 | 9 | 8 | 53 | 2 | 88.9% | 5.89 | 6.62 | 11 | 63 | 1.3 | 3 | 3 | 2 | 6 | 31 | 8 | 1 | 8 | 1 | 50 |
| 6 | Juwan JohnsonNew Orleans Saints·#83 | 14 | 11 | 8 | 105 | 0 | 72.7% | 9.55 | 13.12 | 12 | 95 | 2.0 | 0 | 0 | 0 | 8 | 28 | 11 | 3 | 8 | 0 | 54 |
| 7 | Jake FergusonDallas Cowboys·#87 | 17 | 11 | 7 | 40 | 3 | 63.6% | 3.64 | 5.71 | 5 | 55 | 0.8 | 6 | 3 | 3 | 12 | 44 | 10 | 4 | 7 | 0 | 73 |
| 8 | Travis KelceKansas City Chiefs·#87 | 16 | 9 | 7 | 37 | 2 | 77.8% | 4.11 | 5.29 | 21 | 17 | 0.3 | 4 | 3 | 2 | 5 | 43 | 9 | 1 | 5 | 0 | 69 |
| 9 | Tyler HigbeeLos Angeles Rams·#89 | 10 | 9 | 7 | 60 | 1 | 77.8% | 6.67 | 8.57 | 40 | 24 | 0.7 | 2 | 1 | 1 | 8 | 23 | 8 | 1 | 6 | 0 | 38 |
| 10 | Jake TongesSan Francisco 49ers·#88 | 9 | 7 | 6 | 34 | 3 | 85.7% | 4.86 | 5.67 | 25 | 24 | 0.9 | 3 | 3 | 3 | 9 | 19 | 4 | 4 | 6 | 0 | 27 |
| 11 | Kyle PittsAtlanta Falcons·#8 | 17 | 6 | 6 | 68 | 0 | 100.0% | 11.33 | 11.33 | 25 | 43 | 0.8 | 0 | 0 | 0 | 14 | 34 | 4 | 2 | 6 | 0 | 52 |
| 12 | Mason TaylorNew York Jets·#85 | 11 | 6 | 6 | 34 | 0 | 100.0% | 5.67 | 5.67 | 8 | 26 | 0.9 | 3 | 3 | 0 | 5 | 16 | 6 | 1 | 5 | 0 | 29 |
| 13 | Brock BowersLas Vegas Raiders·#89 | 12 | 5 | 5 | 43 | 1 | 100.0% | 8.60 | 8.60 | 29 | 14 | 0.3 | 1 | 1 | 1 | 3 | 28 | 5 | 2 | 5 | 0 | 46 |
| 14 | Colby ParkinsonLos Angeles Rams·#84 | 12 | 6 | 5 | 45 | 2 | 83.3% | 7.50 | 9.00 | 23 | 44 | 1.3 | 2 | 2 | 2 | 3 | 23 | 5 | 0 | 5 | 0 | 33 |
| 15 | Mark AndrewsBaltimore Ravens·#89 | 15 | 9 | 5 | 25 | 2 | 55.6% | 2.78 | 5.00 | 6 | 40 | 1.0 | 5 | 2 | 2 | 4 | 16 | 9 | 0 | 4 | 1 | 41 |
| 16 | Oronde Gadsden IILos Angeles Chargers·#86 | 13 | 7 | 5 | 32 | 1 | 71.4% | 4.57 | 6.40 | 19 | 7 | 0.3 | 2 | 2 | 1 | 3 | 20 | 6 | 0 | 4 | 0 | 28 |
| 17 | Tyler WarrenIndianapolis Colts·#84 | 14 | 8 | 5 | 31 | 0 | 62.5% | 3.88 | 6.20 | 18 | 27 | 0.5 | 2 | 1 | 0 | 4 | 27 | 6 | 0 | 4 | 1 | 53 |
| 18 | Terrance FergusonLos Angeles Rams·#18 | 11 | 5 | 4 | 88 | 2 | 80.0% | 17.60 | 22.00 | 6 | 84 | 2.2 | 1 | 1 | 1 | 4 | 24 | 5 | 1 | 4 | 0 | 38 |
| 19 | Gunnar HelmTennessee Titans·#84 | 15 | 6 | 4 | 19 | 1 | 66.7% | 3.17 | 4.75 | 8 | 41 | 1.2 | 2 | 2 | 1 | 3 | 15 | 5 | 1 | 3 | 1 | 33 |
| 20 | George KittleSan Francisco 49ers·#85 | 10 | 6 | 4 | 25 | 1 | 66.7% | 4.17 | 6.25 | 4 | 31 | 1.0 | 2 | 2 | 1 | 4 | 19 | 5 | 0 | 4 | 0 | 32 |
| 21 | Michael MayerLas Vegas Raiders·#87 | 12 | 7 | 4 | 33 | 0 | 57.1% | 4.71 | 8.25 | 9 | 66 | 2.9 | 0 | 0 | 0 | 1 | 17 | 6 | 1 | 4 | 0 | 29 |
| 22 | Evan EngramDenver Broncos·#1 | 15 | 7 | 4 | 26 | 0 | 57.1% | 3.71 | 6.50 | 12 | 18 | 0.9 | 1 | 1 | 0 | 2 | 19 | 4 | 1 | 4 | 0 | 40 |
| 23 | AJ BarnerSeattle Seahawks·#88 | 15 | 7 | 4 | 23 | 1 | 57.1% | 3.29 | 5.75 | 15 | 12 | 0.2 | 3 | 1 | 1 | 2 | 23 | 6 | 0 | 4 | 0 | 52 |
| 24 | Sam LaPortaDetroit Lions·#87 | 9 | 6 | 4 | 48 | 0 | 66.7% | 8.00 | 12.00 | 26 | 41 | 1.1 | 0 | 0 | 0 | 1 | 29 | 4 | 2 | 4 | 0 | 38 |
| 25 | Theo JohnsonNew York Giants·#84 | 15 | 5 | 3 | 25 | 2 | 60.0% | 5.00 | 8.33 | 5 | 37 | 0.8 | 3 | 2 | 2 | 5 | 23 | 3 | 2 | 3 | 0 | 46 |
| 26 | T.J. HockensonMinnesota Vikings·#87 | 15 | 5 | 3 | 23 | 1 | 60.0% | 4.60 | 7.67 | 12 | 17 | 0.7 | 2 | 1 | 1 | 8 | 24 | 4 | 2 | 3 | 0 | 46 |
| 27 | Dawson KnoxBuffalo Bills·#88 | 16 | 7 | 3 | 4 | 0 | 42.9% | 0.57 | 1.33 | 9 | 8 | 0.8 | 4 | 2 | 0 | 5 | 28 | 5 | 1 | 1 | 1 | 42 |
| 28 | Drew SampleCincinnati Bengals·#89 | 12 | 3 | 3 | 33 | 0 | 100.0% | 11.00 | 11.00 | 27 | 6 | 0.2 | 0 | 0 | 0 | 6 | 18 | 1 | 1 | 3 | 0 | 27 |
| 29 | Mike GesickiCincinnati Bengals·#88 | 12 | 6 | 3 | 9 | 0 | 50.0% | 1.50 | 3.00 | 1 | 13 | 0.6 | 3 | 1 | 0 | 9 | 23 | 6 | 3 | 2 | 0 | 34 |
| 30 | Adam TrautmanDenver Broncos·#82 | 11 | 3 | 3 | 35 | 1 | 100.0% | 11.67 | 11.67 | 23 | 12 | 0.4 | 1 | 1 | 1 | 2 | 16 | 3 | 1 | 3 | 0 | 29 |
| 31 | Tucker KraftGreen Bay Packers·#85 | 8 | 5 | 3 | 44 | 0 | 60.0% | 8.80 | 14.67 | 34 | 20 | 1.0 | 1 | 1 | 0 | 4 | 14 | 4 | 1 | 3 | 0 | 26 |
| 32 | Tommy TrembleCarolina Panthers·#82 | 15 | 4 | 3 | 20 | 0 | 75.0% | 5.00 | 6.67 | 18 | 6 | 0.2 | 0 | 0 | 0 | 1 | 23 | 2 | 1 | 1 | 0 | 36 |
| 33 | Zach ErtzWashington Commanders·#86 | 11 | 6 | 3 | 20 | 0 | 50.0% | 3.33 | 6.67 | 6 | 57 | 1.1 | 3 | 1 | 0 | 5 | 20 | 5 | 1 | 2 | 0 | 50 |
| 34 | Noah GrayKansas City Chiefs·#83 | 13 | 6 | 3 | 15 | 0 | 50.0% | 2.50 | 5.00 | 16 | 45 | 1.8 | 1 | 0 | 0 | 2 | 14 | 5 | 0 | 2 | 0 | 25 |
| 35 | Cade OttonTampa Bay Buccaneers·#88 | 16 | 4 | 2 | 11 | 0 | 50.0% | 2.75 | 5.50 | 6 | 16 | 0.3 | 0 | 0 | 0 | 12 | 35 | 4 | 2 | 1 | 1 | 60 |
| 36 | Brenton StrangeJacksonville Jaguars·#85 | 12 | 4 | 2 | 13 | 1 | 50.0% | 3.25 | 6.50 | 4 | 20 | 0.7 | 3 | 1 | 1 | 4 | 16 | 4 | 0 | 2 | 0 | 27 |
| 37 | Chig OkonkwoTennessee Titans·#85 | 16 | 3 | 2 | 58 | 1 | 66.7% | 19.33 | 29.00 | 38 | 22 | 0.5 | 0 | 0 | 0 | 4 | 20 | 3 | 2 | 2 | 0 | 43 |
| 38 | Cole KmetChicago Bears·#85 | 15 | 6 | 2 | 16 | 0 | 33.3% | 2.67 | 8.00 | 13 | 45 | 1.2 | 1 | 0 | 0 | 2 | 26 | 3 | 1 | 2 | 0 | 54 |
| 39 | Davis AllenLos Angeles Rams·#87 | 13 | 4 | 2 | 8 | 0 | 50.0% | 2.00 | 4.00 | 5 | 4 | 0.1 | 2 | 0 | 0 | 2 | 25 | 3 | 0 | 2 | 0 | 33 |
| 40 | Darnell WashingtonPittsburgh Steelers·#80 | 11 | 4 | 2 | 16 | 1 | 50.0% | 4.00 | 8.00 | 10 | 6 | 0.4 | 3 | 1 | 1 | 7 | 18 | 4 | 2 | 2 | 1 | 31 |
| 41 | Daniel BellingerNew York Giants·#82 | 14 | 3 | 2 | 27 | 0 | 66.7% | 9.00 | 13.50 | 22 | 24 | 0.9 | 1 | 0 | 0 | 2 | 17 | 2 | 1 | 2 | 0 | 28 |
| 42 | Jonnu SmithPittsburgh Steelers·#81 | 12 | 2 | 2 | 6 | 1 | 100.0% | 3.00 | 3.00 | 10 | -4 | -0.1 | 1 | 1 | 1 | 6 | 14 | 0 | 3 | 2 | 0 | 27 |
| 43 | Harold Fannin Jr.Cleveland Browns·#44 | 13 | 3 | 2 | 19 | 1 | 66.7% | 6.33 | 9.50 | 8 | 32 | 0.9 | 1 | 1 | 1 | 2 | 14 | 3 | 1 | 2 | 1 | 34 |
| 44 | Pat FreiermuthPittsburgh Steelers·#88 | 13 | 3 | 2 | 23 | 1 | 66.7% | 7.67 | 11.50 | 3 | 20 | 0.8 | 2 | 1 | 1 | 8 | 19 | 2 | 3 | 2 | 0 | 33 |
| 45 | Ja'Tavion SandersCarolina Panthers·#0 | 12 | 1 | 1 | 7 | 0 | 100.0% | 7.00 | 7.00 | 2 | 5 | 0.2 | 1 | 1 | 0 | 4 | 21 | 1 | 2 | 1 | 0 | 31 |
| 46 | Elijah HigginsArizona Cardinals·#84 | 12 | 1 | 1 | 10 | 0 | 100.0% | 10.00 | 10.00 | 4 | 6 | 0.2 | 0 | 0 | 0 | 3 | 17 | 0 | 2 | 1 | 0 | 25 |