| 1 | Justin HerbertLos Angeles Chargers·#10 | 16 | 58 | 34 | 58.6% | 321 | 5.53 | 3 | 2 | 3.5% | 3 | 549 | 9.5 | 3.07 | 3.07 | 4 | 26 | 0 | 4 | 3 | 0 | 87 |
| 2 | Patrick MahomesKansas City Chiefs·#15 | 14 | 41 | 24 | 58.5% | 295 | 7.20 | 3 | 2 | 4.9% | 3 | 392 | 9.6 | 3.00 | 3.00 | 6 | 49 | 0 | 1 | 4 | 0 | 62 |
| 3 | Drake MayeNew England Patriots·#10 | 16 | 24 | 17 | 70.8% | 266 | 11.08 | 1 | 0 | 0.0% | 8 | 260 | 10.8 | 3.05 | 3.05 | 2 | 9 | 1 | 0 | 1 | 0 | 66 |
| 4 | Daniel JonesIndianapolis Colts·#17 | 13 | 31 | 21 | 67.7% | 273 | 8.81 | 5 | 1 | 3.2% | 2 | 253 | 7.2 | 2.73 | 2.73 | 1 | 6 | 0 | 1 | 0 | 1 | 55 |
| 5 | Jordan LoveGreen Bay Packers·#10 | 14 | 43 | 25 | 58.1% | 370 | 8.60 | 1 | 0 | 0.0% | 5 | 488 | 11.1 | 2.79 | 2.79 | 4 | 26 | 0 | 2 | 3 | 1 | 79 |
| 6 | Cam WardTennessee Titans·#1 | 17 | 64 | 31 | 48.4% | 290 | 4.53 | 1 | 2 | 3.1% | 6 | 601 | 9.4 | 2.65 | 2.65 | 4 | 15 | 1 | 1 | 4 | 0 | 96 |
| 7 | Joe BurrowCincinnati Bengals·#9 | 7 | 17 | 14 | 82.3% | 94 | 5.53 | 3 | 0 | 0.0% | 4 | 75 | 4.2 | 2.90 | 2.90 | 0 | 0 | 0 | 2 | 2 | 0 | 38 |
| 8 | Tua TagovailoaMiami Dolphins·#1 | 12 | 14 | 11 | 78.6% | 99 | 7.07 | 3 | 0 | 0.0% | 5 | 96 | 6.4 | 3.12 | 3.12 | 0 | 0 | 0 | 1 | 1 | 0 | 27 |
| 9 | Baker MayfieldTampa Bay Buccaneers·#6 | 17 | 35 | 20 | 57.1% | 301 | 8.60 | 3 | 1 | 2.9% | 4 | 348 | 9.7 | 2.77 | 2.77 | 4 | 24 | 0 | 2 | 0 | 0 | 60 |
| 10 | Aaron RodgersPittsburgh Steelers·#8 | 13 | 10 | 6 | 60.0% | 38 | 3.80 | 1 | 0 | 0.0% | 5 | 62 | 5.6 | 2.69 | 2.69 | 2 | 7 | 0 | 1 | 1 | 0 | 27 |
| 11 | Jared GoffDetroit Lions·#16 | 17 | 28 | 18 | 64.3% | 198 | 7.07 | 0 | 0 | 0.0% | 3 | 173 | 6.2 | 2.64 | 2.64 | 1 | 2 | 0 | 0 | 3 | 0 | 58 |
| 12 | Geno SmithLas Vegas Raiders·#7 | 15 | 41 | 29 | 70.7% | 233 | 5.68 | 2 | 3 | 7.3% | 3 | 190 | 4.6 | 2.46 | 2.46 | 1 | 9 | 0 | 0 | 1 | 0 | 59 |
| 13 | Jacoby BrissettArizona Cardinals·#7 | 12 | 18 | 11 | 61.1% | 123 | 6.83 | 1 | 0 | 0.0% | 2 | 69 | 3.8 | 2.73 | 2.73 | 0 | 0 | 0 | 0 | 2 | 0 | 44 |
| 14 | Lamar JacksonBaltimore Ravens·#38 | 13 | 35 | 18 | 51.4% | 344 | 9.83 | 3 | 0 | 0.0% | 5 | 403 | 10.9 | 2.78 | 2.78 | 3 | 23 | 0 | 0 | 2 | 2 | 60 |
| 15 | Caleb WilliamsChicago Bears·#18 | 17 | 32 | 17 | 53.1% | 173 | 5.41 | 1 | 0 | 0.0% | 3 | 241 | 7.1 | 3.05 | 3.05 | 5 | 29 | 0 | 1 | 2 | 1 | 83 |
| 16 | Josh AllenBuffalo Bills·#17 | 14 | 27 | 16 | 59.3% | 183 | 6.78 | 0 | 0 | 0.0% | 0 | 178 | 6.6 | 2.95 | 2.95 | 3 | 12 | 0 | 0 | 1 | 0 | 53 |
| 17 | J.J. McCarthyMinnesota Vikings·#9 | 8 | 11 | 7 | 63.6% | 63 | 5.73 | 1 | 0 | 0.0% | 2 | 67 | 5.6 | 2.70 | 2.70 | 5 | 33 | 1 | 0 | 1 | 0 | 27 |
| 18 | Trevor LawrenceJacksonville Jaguars·#16 | 11 | 24 | 13 | 54.2% | 145 | 6.04 | 2 | 1 | 4.2% | 1 | 77 | 3.2 | 2.56 | 2.56 | 3 | 16 | 1 | 0 | 2 | 0 | 41 |
| 19 | Tyler ShoughNew Orleans Saints·#6 | 10 | 14 | 10 | 71.4% | 101 | 7.21 | 0 | 1 | 7.1% | 2 | 98 | 7.0 | 2.79 | 2.79 | 1 | 4 | 0 | 1 | 0 | 1 | 26 |
| 20 | Bo NixDenver Broncos·#10 | 17 | 25 | 13 | 52.0% | 140 | 5.60 | 2 | 0 | 0.0% | 0 | 181 | 7.0 | 3.38 | 3.38 | 7 | 55 | 2 | 0 | 3 | 0 | 53 |
| 21 | Matthew StaffordLos Angeles Rams·#9 | 17 | 25 | 17 | 68.0% | 131 | 5.24 | 4 | 1 | 4.0% | 1 | 206 | 8.2 | 2.75 | 2.75 | 0 | 0 | 0 | 0 | 2 | 1 | 45 |
| 22 | C.J. StroudHouston Texans·#7 | 11 | 24 | 14 | 58.3% | 128 | 5.33 | 3 | 0 | 0.0% | 2 | 142 | 5.7 | 2.82 | 2.82 | 4 | 43 | 0 | 0 | 1 | 0 | 61 |
| 23 | Michael Penix Jr.Atlanta Falcons·#9 | 8 | 23 | 13 | 56.5% | 98 | 4.26 | 3 | 1 | 4.3% | 0 | 179 | 7.5 | 2.20 | 2.20 | 0 | 0 | 0 | 1 | 0 | 0 | 28 |
| 24 | Brock PurdySan Francisco 49ers·#13 | 9 | 16 | 8 | 50.0% | 99 | 6.19 | 1 | 1 | 6.3% | 1 | 144 | 8.5 | 2.74 | 2.74 | 1 | 5 | 0 | 1 | 0 | 0 | 28 |