| 1 | Trey McBrideArizona Cardinals·#85 | 17 | 170 | 126 | 1,246 | 11 | 74.1% | 7.33 | 9.89 | 583 | 1,058 | 1.6 | 34 | 20 | 11 | 109 | 427 | 124 | 23 | 64 | 6 | 714 |
| 2 | Jake FergusonDallas Cowboys·#87 | 17 | 102 | 82 | 602 | 8 | 80.4% | 5.90 | 7.34 | 307 | 403 | 0.8 | 25 | 15 | 7 | 67 | 374 | 70 | 17 | 32 | 3 | 532 |
| 3 | Juwan JohnsonNew Orleans Saints·#83 | 17 | 102 | 77 | 889 | 3 | 75.5% | 8.72 | 11.55 | 362 | 614 | 1.4 | 8 | 5 | 2 | 71 | 356 | 87 | 21 | 41 | 7 | 565 |
| 4 | Kyle PittsAtlanta Falcons·#8 | 17 | 117 | 88 | 928 | 5 | 75.2% | 7.93 | 10.55 | 400 | 821 | 1.5 | 12 | 7 | 5 | 80 | 355 | 82 | 13 | 52 | 4 | 578 |
| 5 | Cade OttonTampa Bay Buccaneers·#88 | 16 | 81 | 59 | 572 | 1 | 72.8% | 7.06 | 9.69 | 309 | 383 | 0.7 | 7 | 3 | 1 | 57 | 353 | 57 | 10 | 25 | 4 | 570 |
| 6 | Tyler WarrenIndianapolis Colts·#84 | 17 | 113 | 76 | 817 | 4 | 67.3% | 7.23 | 10.75 | 474 | 536 | 1.1 | 23 | 11 | 4 | 81 | 351 | 88 | 19 | 42 | 6 | 550 |
| 7 | Travis KelceKansas City Chiefs·#87 | 17 | 106 | 76 | 853 | 5 | 71.7% | 8.05 | 11.22 | 424 | 637 | 1.1 | 13 | 9 | 3 | 39 | 340 | 88 | 5 | 46 | 1 | 605 |
| 8 | Dalton SchultzHouston Texans·#86 | 17 | 107 | 82 | 777 | 3 | 76.6% | 7.26 | 9.48 | 358 | 584 | 1.2 | 12 | 5 | 3 | 55 | 340 | 83 | 9 | 39 | 2 | 546 |
| 9 | Hunter HenryNew England Patriots·#85 | 17 | 87 | 60 | 768 | 7 | 69.0% | 8.83 | 12.80 | 335 | 575 | 1.4 | 22 | 14 | 5 | 61 | 325 | 68 | 27 | 42 | 4 | 514 |
| 10 | Theo JohnsonNew York Giants·#84 | 15 | 74 | 45 | 528 | 5 | 60.8% | 7.14 | 11.73 | 187 | 580 | 1.3 | 14 | 6 | 4 | 56 | 288 | 54 | 11 | 25 | 3 | 486 |
| 11 | AJ BarnerSeattle Seahawks·#88 | 17 | 67 | 52 | 519 | 6 | 77.6% | 7.75 | 9.98 | 271 | 310 | 0.7 | 13 | 10 | 5 | 37 | 273 | 50 | 12 | 26 | 5 | 442 |
| 12 | Harold Fannin Jr.Cleveland Browns·#44 | 16 | 108 | 72 | 731 | 6 | 66.7% | 6.77 | 10.15 | 352 | 632 | 1.4 | 11 | 7 | 4 | 58 | 270 | 76 | 10 | 32 | 4 | 470 |
| 13 | Dallas GoedertPhiladelphia Eagles·#88 | 15 | 82 | 60 | 591 | 11 | 73.2% | 7.21 | 9.85 | 234 | 462 | 1.3 | 15 | 13 | 10 | 45 | 269 | 56 | 13 | 34 | 5 | 462 |
| 14 | T.J. HockensonMinnesota Vikings·#87 | 15 | 66 | 51 | 438 | 3 | 77.3% | 6.64 | 8.59 | 219 | 314 | 0.7 | 11 | 8 | 3 | 64 | 268 | 40 | 15 | 23 | 4 | 457 |
| 15 | Chig OkonkwoTennessee Titans·#85 | 17 | 78 | 56 | 560 | 2 | 71.8% | 7.18 | 10.00 | 342 | 288 | 0.8 | 5 | 3 | 1 | 47 | 258 | 47 | 12 | 24 | 7 | 455 |
| 16 | Brock BowersLas Vegas Raiders·#89 | 12 | 85 | 64 | 682 | 7 | 75.3% | 8.02 | 10.66 | 305 | 450 | 1.3 | 18 | 10 | 6 | 43 | 255 | 77 | 9 | 36 | 1 | 414 |
| 17 | Evan EngramDenver Broncos·#1 | 16 | 77 | 50 | 461 | 1 | 64.9% | 5.99 | 9.22 | 302 | 257 | 0.9 | 11 | 7 | 1 | 40 | 251 | 39 | 7 | 19 | 1 | 373 |
| 18 | Oronde Gadsden IILos Angeles Chargers·#86 | 15 | 68 | 49 | 664 | 3 | 72.1% | 9.76 | 13.55 | 221 | 541 | 1.5 | 15 | 7 | 3 | 47 | 247 | 57 | 5 | 28 | 4 | 408 |
| 19 | Cole KmetChicago Bears·#85 | 16 | 49 | 30 | 349 | 2 | 61.2% | 7.12 | 11.63 | 149 | 322 | 1.1 | 7 | 3 | 1 | 41 | 241 | 34 | 16 | 17 | 0 | 414 |
| 20 | Colston LovelandChicago Bears·#84 | 16 | 83 | 58 | 713 | 6 | 69.9% | 8.59 | 12.29 | 250 | 656 | 1.8 | 15 | 10 | 4 | 51 | 236 | 70 | 13 | 36 | 1 | 413 |
| 21 | Colby ParkinsonLos Angeles Rams·#84 | 15 | 55 | 43 | 408 | 8 | 78.2% | 7.42 | 9.49 | 271 | 251 | 0.8 | 21 | 15 | 6 | 35 | 219 | 32 | 8 | 24 | 2 | 308 |
| 22 | Mark AndrewsBaltimore Ravens·#89 | 17 | 68 | 48 | 422 | 5 | 70.6% | 6.21 | 8.79 | 101 | 478 | 1.3 | 15 | 6 | 4 | 50 | 217 | 56 | 12 | 24 | 6 | 375 |
| 23 | George KittleSan Francisco 49ers·#85 | 11 | 69 | 57 | 628 | 7 | 82.6% | 9.10 | 11.02 | 252 | 426 | 1.4 | 13 | 12 | 6 | 45 | 216 | 54 | 3 | 38 | 3 | 319 |
| 24 | Mason TaylorNew York Jets·#85 | 13 | 66 | 44 | 371 | 1 | 66.7% | 5.62 | 8.43 | 133 | 354 | 0.9 | 9 | 7 | 1 | 57 | 216 | 52 | 10 | 23 | 3 | 398 |
| 25 | Zach ErtzWashington Commanders·#86 | 13 | 72 | 50 | 506 | 4 | 69.4% | 7.03 | 10.12 | 123 | 649 | 1.6 | 9 | 6 | 4 | 45 | 211 | 61 | 9 | 25 | 1 | 411 |
| 26 | Pat FreiermuthPittsburgh Steelers·#88 | 17 | 54 | 41 | 486 | 4 | 75.9% | 9.00 | 11.85 | 255 | 296 | 0.9 | 9 | 5 | 3 | 44 | 211 | 37 | 11 | 22 | 1 | 350 |
| 27 | Brenton StrangeJacksonville Jaguars·#85 | 12 | 60 | 46 | 540 | 3 | 76.7% | 9.00 | 11.74 | 247 | 396 | 1.2 | 10 | 6 | 2 | 44 | 208 | 43 | 5 | 28 | 1 | 341 |
| 28 | Dawson KnoxBuffalo Bills·#88 | 17 | 50 | 36 | 419 | 4 | 72.0% | 8.38 | 11.64 | 183 | 282 | 1.0 | 13 | 7 | 4 | 35 | 206 | 38 | 5 | 23 | 3 | 327 |
| 29 | Jonnu SmithPittsburgh Steelers·#81 | 17 | 55 | 38 | 222 | 2 | 69.1% | 4.04 | 5.84 | 179 | 166 | 0.7 | 8 | 5 | 2 | 40 | 203 | 31 | 11 | 11 | 3 | 342 |
| 30 | Sam LaPortaDetroit Lions·#87 | 9 | 49 | 40 | 489 | 3 | 81.6% | 9.98 | 12.22 | 274 | 274 | 1.0 | 6 | 4 | 2 | 22 | 201 | 32 | 5 | 23 | 1 | 275 |
| 31 | Drew SampleCincinnati Bengals·#89 | 17 | 20 | 15 | 106 | 1 | 75.0% | 5.30 | 7.07 | 109 | -7 | -0.0 | 1 | 1 | 1 | 38 | 197 | 4 | 8 | 5 | 1 | 290 |
| 32 | Elijah HigginsArizona Cardinals·#84 | 17 | 37 | 30 | 301 | 0 | 81.1% | 8.14 | 10.03 | 209 | 139 | 0.5 | 5 | 2 | 0 | 56 | 189 | 18 | 12 | 15 | 2 | 304 |
| 33 | Tommy TrembleCarolina Panthers·#82 | 17 | 37 | 27 | 249 | 2 | 73.0% | 6.73 | 9.22 | 164 | 124 | 0.5 | 5 | 4 | 2 | 27 | 188 | 31 | 6 | 10 | 3 | 303 |
| 34 | David NjokuCleveland Browns·#85 | 12 | 48 | 33 | 293 | 4 | 68.8% | 6.10 | 8.88 | 160 | 253 | 0.8 | 9 | 6 | 4 | 40 | 185 | 33 | 7 | 11 | 3 | 310 |
| 35 | Adam TrautmanDenver Broncos·#82 | 17 | 23 | 20 | 195 | 1 | 87.0% | 8.48 | 9.75 | 104 | 97 | 0.4 | 1 | 1 | 1 | 30 | 184 | 18 | 5 | 11 | 1 | 294 |
| 36 | Jake TongesSan Francisco 49ers·#88 | 13 | 46 | 34 | 293 | 5 | 73.9% | 6.37 | 8.62 | 143 | 222 | 0.9 | 7 | 6 | 4 | 35 | 177 | 27 | 9 | 21 | 2 | 246 |
| 37 | Darnell WashingtonPittsburgh Steelers·#80 | 16 | 44 | 31 | 366 | 1 | 70.5% | 8.32 | 11.81 | 229 | 222 | 0.9 | 9 | 6 | 1 | 22 | 176 | 31 | 4 | 17 | 4 | 263 |
| 38 | Davis AllenLos Angeles Rams·#87 | 17 | 33 | 24 | 214 | 3 | 72.7% | 6.48 | 8.92 | 137 | 130 | 0.6 | 7 | 5 | 3 | 17 | 169 | 20 | 5 | 12 | 2 | 230 |
| 39 | Noah GrayKansas City Chiefs·#83 | 16 | 38 | 21 | 178 | 0 | 55.3% | 4.68 | 8.48 | 107 | 219 | 0.8 | 3 | 1 | 0 | 14 | 167 | 29 | 3 | 9 | 1 | 305 |
| 40 | Mike GesickiCincinnati Bengals·#88 | 13 | 42 | 28 | 307 | 2 | 66.7% | 7.31 | 10.96 | 63 | 345 | 1.6 | 8 | 3 | 2 | 56 | 163 | 36 | 11 | 19 | 2 | 253 |
| 41 | Gunnar HelmTennessee Titans·#84 | 16 | 55 | 44 | 357 | 2 | 80.0% | 6.49 | 8.11 | 159 | 269 | 1.1 | 8 | 5 | 1 | 30 | 159 | 35 | 6 | 17 | 2 | 288 |
| 42 | Michael MayerLas Vegas Raiders·#87 | 13 | 48 | 35 | 328 | 1 | 72.9% | 6.83 | 9.37 | 196 | 218 | 0.9 | 6 | 5 | 1 | 26 | 157 | 32 | 4 | 18 | 0 | 259 |
| 43 | Daniel BellingerNew York Giants·#82 | 16 | 26 | 19 | 286 | 2 | 73.1% | 11.00 | 15.05 | 132 | 241 | 0.9 | 6 | 4 | 0 | 37 | 155 | 21 | 6 | 14 | 2 | 257 |
| 44 | Tucker KraftGreen Bay Packers·#85 | 8 | 44 | 32 | 489 | 6 | 72.7% | 11.11 | 15.28 | 344 | 195 | 0.8 | 12 | 9 | 5 | 19 | 154 | 32 | 4 | 22 | 1 | 237 |
| 45 | Isaiah LikelyBaltimore Ravens·#80 | 14 | 36 | 27 | 307 | 1 | 75.0% | 8.53 | 11.37 | 117 | 287 | 1.1 | 6 | 2 | 1 | 33 | 152 | 25 | 6 | 11 | 3 | 255 |
| 46 | Noah FantCincinnati Bengals·#86 | 15 | 41 | 34 | 288 | 3 | 82.9% | 7.02 | 8.47 | 174 | 118 | 0.6 | 4 | 2 | 2 | 36 | 151 | 24 | 6 | 13 | 4 | 219 |
| 47 | Ja'Tavion SandersCarolina Panthers·#0 | 12 | 34 | 29 | 190 | 1 | 85.3% | 5.59 | 6.55 | 86 | 145 | 0.7 | 10 | 8 | 1 | 32 | 150 | 24 | 3 | 8 | 3 | 246 |
| 48 | Jeremy RuckertNew York Jets·#89 | 17 | 29 | 23 | 168 | 1 | 79.3% | 5.79 | 7.30 | 88 | 91 | 0.4 | 3 | 1 | 1 | 32 | 146 | 20 | 6 | 8 | 2 | 241 |
| 49 | Dalton KincaidBuffalo Bills·#86 | 12 | 50 | 39 | 571 | 5 | 78.0% | 11.42 | 14.64 | 259 | 425 | 2.2 | 9 | 6 | 3 | 33 | 145 | 37 | 5 | 27 | 1 | 213 |
| 50 | Charlie WoernerAtlanta Falcons·#89 | 17 | 9 | 8 | 48 | 0 | 88.9% | 5.33 | 6.00 | 35 | 13 | 0.1 | 1 | 1 | 0 | 28 | 145 | 4 | 3 | 2 | 3 | 217 |