| 1 | Tyler WarrenIndianapolis Colts·#84 | 17 | 37 | 26 | 317 | 1 | 70.3% | 8.57 | 12.19 | 187 | 243 | 1.7 | 7 | 3 | 1 | 22 | 96 | 30 | 7 | 16 | 0 | 152 |
| 2 | Trey McBrideArizona Cardinals·#85 | 17 | 34 | 25 | 252 | 0 | 73.5% | 7.41 | 10.08 | 156 | 139 | 1.1 | 3 | 2 | 0 | 19 | 83 | 18 | 6 | 13 | 3 | 144 |
| 3 | Kyle PittsAtlanta Falcons·#8 | 17 | 26 | 18 | 239 | 0 | 69.2% | 9.19 | 13.28 | 73 | 268 | 2.2 | 1 | 0 | 0 | 17 | 80 | 22 | 3 | 13 | 2 | 136 |
| 4 | Jake FergusonDallas Cowboys·#87 | 17 | 20 | 16 | 88 | 1 | 80.0% | 4.40 | 5.50 | 45 | 61 | 0.6 | 7 | 4 | 1 | 10 | 74 | 16 | 4 | 2 | 0 | 105 |
| 5 | Dalton SchultzHouston Texans·#86 | 17 | 22 | 19 | 240 | 0 | 86.4% | 10.91 | 12.63 | 114 | 142 | 1.5 | 3 | 2 | 0 | 12 | 73 | 19 | 1 | 11 | 0 | 117 |
| 6 | Cade OttonTampa Bay Buccaneers·#88 | 16 | 16 | 12 | 123 | 1 | 75.0% | 7.69 | 10.25 | 49 | 110 | 1.0 | 1 | 1 | 1 | 16 | 73 | 15 | 3 | 5 | 0 | 114 |
| 7 | Theo JohnsonNew York Giants·#84 | 15 | 18 | 9 | 65 | 2 | 50.0% | 3.61 | 7.22 | 34 | 69 | 0.9 | 5 | 3 | 2 | 8 | 66 | 12 | 2 | 4 | 0 | 100 |
| 8 | Juwan JohnsonNew Orleans Saints·#83 | 17 | 21 | 16 | 215 | 0 | 76.2% | 10.24 | 13.44 | 95 | 121 | 1.4 | 1 | 1 | 0 | 15 | 66 | 16 | 4 | 8 | 3 | 101 |
| 9 | Harold Fannin Jr.Cleveland Browns·#44 | 16 | 26 | 20 | 190 | 4 | 76.9% | 7.31 | 9.50 | 100 | 103 | 1.1 | 4 | 4 | 3 | 12 | 66 | 21 | 1 | 11 | 0 | 97 |
| 10 | Travis KelceKansas City Chiefs·#87 | 17 | 21 | 15 | 150 | 2 | 71.4% | 7.14 | 10.00 | 78 | 113 | 1.0 | 3 | 3 | 2 | 5 | 65 | 17 | 0 | 8 | 0 | 114 |
| 11 | Chig OkonkwoTennessee Titans·#85 | 17 | 18 | 15 | 135 | 0 | 83.3% | 7.50 | 9.00 | 85 | 59 | 0.6 | 0 | 0 | 0 | 7 | 61 | 8 | 1 | 7 | 0 | 96 |
| 12 | T.J. HockensonMinnesota Vikings·#87 | 15 | 8 | 7 | 56 | 1 | 87.5% | 7.00 | 8.00 | 39 | 17 | 0.2 | 1 | 1 | 1 | 11 | 59 | 3 | 2 | 3 | 0 | 86 |
| 13 | Hunter HenryNew England Patriots·#85 | 17 | 10 | 5 | 85 | 0 | 50.0% | 8.50 | 17.00 | 24 | 78 | 1.1 | 3 | 2 | 0 | 13 | 59 | 10 | 7 | 4 | 1 | 98 |
| 14 | Cole KmetChicago Bears·#85 | 16 | 6 | 5 | 38 | 0 | 83.3% | 6.33 | 7.60 | 25 | 26 | 0.5 | 0 | 0 | 0 | 10 | 57 | 3 | 2 | 2 | 0 | 97 |
| 15 | Brenton StrangeJacksonville Jaguars·#85 | 12 | 17 | 13 | 185 | 0 | 76.5% | 10.88 | 14.23 | 100 | 144 | 1.6 | 3 | 2 | 0 | 11 | 57 | 10 | 1 | 8 | 1 | 93 |
| 16 | Sam LaPortaDetroit Lions·#87 | 9 | 15 | 13 | 195 | 2 | 86.7% | 13.00 | 15.00 | 110 | 101 | 1.4 | 2 | 2 | 1 | 6 | 56 | 10 | 0 | 11 | 1 | 72 |
| 17 | Dallas GoedertPhiladelphia Eagles·#88 | 15 | 18 | 14 | 98 | 4 | 77.8% | 5.44 | 7.00 | 39 | 71 | 1.0 | 5 | 5 | 4 | 6 | 55 | 12 | 3 | 7 | 1 | 100 |
| 18 | Mark AndrewsBaltimore Ravens·#89 | 17 | 20 | 16 | 124 | 1 | 80.0% | 6.20 | 7.75 | 29 | 136 | 1.6 | 2 | 1 | 1 | 13 | 55 | 19 | 2 | 8 | 1 | 85 |
| 19 | AJ BarnerSeattle Seahawks·#88 | 17 | 11 | 9 | 72 | 1 | 81.8% | 6.55 | 8.00 | 32 | 43 | 0.5 | 1 | 1 | 1 | 6 | 54 | 9 | 2 | 4 | 0 | 89 |
| 20 | Brock BowersLas Vegas Raiders·#89 | 12 | 17 | 13 | 136 | 1 | 76.5% | 8.00 | 10.46 | 57 | 92 | 1.2 | 3 | 1 | 1 | 8 | 52 | 16 | 0 | 5 | 0 | 82 |
| 21 | Darnell WashingtonPittsburgh Steelers·#80 | 16 | 10 | 5 | 84 | 0 | 50.0% | 8.40 | 16.80 | 43 | 48 | 0.9 | 2 | 0 | 0 | 11 | 51 | 8 | 1 | 4 | 0 | 76 |
| 22 | Colby ParkinsonLos Angeles Rams·#84 | 15 | 13 | 10 | 108 | 0 | 76.9% | 8.31 | 10.80 | 83 | 50 | 0.7 | 5 | 3 | 0 | 11 | 49 | 7 | 1 | 5 | 0 | 77 |
| 23 | Tucker KraftGreen Bay Packers·#85 | 8 | 11 | 9 | 174 | 2 | 81.8% | 15.82 | 19.33 | 131 | 78 | 1.1 | 4 | 3 | 2 | 4 | 48 | 9 | 2 | 7 | 0 | 68 |
| 24 | Daniel BellingerNew York Giants·#82 | 15 | 7 | 5 | 99 | 1 | 71.4% | 14.14 | 19.80 | 30 | 98 | 1.3 | 1 | 1 | 0 | 12 | 48 | 6 | 2 | 4 | 0 | 78 |
| 25 | Zach ErtzWashington Commanders·#86 | 13 | 16 | 11 | 67 | 2 | 68.8% | 4.19 | 6.09 | 29 | 127 | 1.5 | 2 | 2 | 2 | 7 | 47 | 14 | 1 | 4 | 0 | 83 |
| 26 | Charlie WoernerAtlanta Falcons·#89 | 17 | 2 | 1 | -5 | 0 | 50.0% | -2.50 | -5.00 | 0 | -5 | -0.1 | 0 | 0 | 0 | 11 | 47 | 0 | 1 | 0 | 1 | 70 |
| 27 | Colston LovelandChicago Bears·#84 | 16 | 15 | 7 | 108 | 0 | 46.7% | 7.20 | 15.43 | 58 | 143 | 2.0 | 1 | 1 | 0 | 13 | 47 | 13 | 1 | 4 | 0 | 83 |
| 28 | Jonnu SmithPittsburgh Steelers·#81 | 17 | 16 | 12 | 80 | 1 | 75.0% | 5.00 | 6.67 | 55 | 71 | 1.2 | 3 | 3 | 1 | 9 | 46 | 7 | 2 | 5 | 0 | 71 |
| 29 | Oronde Gadsden IILos Angeles Chargers·#86 | 15 | 13 | 8 | 97 | 1 | 61.5% | 7.46 | 12.12 | 34 | 100 | 1.6 | 2 | 1 | 1 | 9 | 46 | 12 | 1 | 4 | 1 | 71 |
| 30 | Drew SampleCincinnati Bengals·#89 | 16 | 5 | 3 | 22 | 0 | 60.0% | 4.40 | 7.33 | 25 | -7 | -0.1 | 0 | 0 | 0 | 7 | 45 | 2 | 1 | 1 | 0 | 66 |
| 31 | George KittleSan Francisco 49ers·#85 | 11 | 12 | 11 | 147 | 2 | 91.7% | 12.25 | 13.36 | 45 | 105 | 1.5 | 1 | 1 | 1 | 8 | 44 | 10 | 1 | 9 | 1 | 70 |
| 32 | Pat FreiermuthPittsburgh Steelers·#88 | 17 | 4 | 4 | 29 | 0 | 100.0% | 7.25 | 7.25 | 8 | 21 | 0.3 | 0 | 0 | 0 | 6 | 43 | 3 | 1 | 1 | 0 | 66 |
| 33 | Tommy TrembleCarolina Panthers·#82 | 17 | 8 | 5 | 44 | 1 | 62.5% | 5.50 | 8.80 | 29 | 14 | 0.4 | 2 | 2 | 1 | 3 | 43 | 7 | 3 | 4 | 2 | 67 |
| 34 | Adam TrautmanDenver Broncos·#82 | 15 | 6 | 5 | 53 | 0 | 83.3% | 8.83 | 10.60 | 24 | 31 | 0.5 | 0 | 0 | 0 | 8 | 42 | 4 | 0 | 2 | 0 | 58 |
| 35 | Elijah HigginsArizona Cardinals·#84 | 16 | 9 | 8 | 87 | 0 | 88.9% | 9.67 | 10.88 | 46 | 41 | 0.7 | 1 | 0 | 0 | 10 | 41 | 7 | 3 | 6 | 0 | 68 |
| 36 | Michael MayerLas Vegas Raiders·#87 | 13 | 14 | 10 | 83 | 0 | 71.4% | 5.93 | 8.30 | 46 | 73 | 1.0 | 2 | 1 | 0 | 7 | 39 | 9 | 0 | 3 | 0 | 72 |
| 37 | Tyler HigbeeLos Angeles Rams·#89 | 10 | 11 | 8 | 87 | 1 | 72.7% | 7.91 | 10.88 | 50 | 38 | 0.7 | 3 | 2 | 1 | 6 | 39 | 6 | 1 | 6 | 0 | 55 |
| 38 | Evan EngramDenver Broncos·#1 | 15 | 13 | 9 | 94 | 0 | 69.2% | 7.23 | 10.44 | 46 | 64 | 1.3 | 3 | 2 | 0 | 6 | 39 | 7 | 0 | 4 | 1 | 61 |
| 39 | Austin HooperNew England Patriots·#81 | 16 | 7 | 6 | 70 | 1 | 85.7% | 10.00 | 11.67 | 43 | 42 | 0.7 | 2 | 2 | 1 | 3 | 39 | 5 | 2 | 4 | 1 | 59 |
| 40 | Dawson KnoxBuffalo Bills·#88 | 17 | 12 | 10 | 127 | 2 | 83.3% | 10.58 | 12.70 | 47 | 93 | 1.7 | 3 | 3 | 2 | 6 | 39 | 10 | 1 | 6 | 2 | 63 |
| 41 | Isaiah LikelyBaltimore Ravens·#80 | 14 | 11 | 7 | 78 | 0 | 63.6% | 7.09 | 11.14 | 46 | 81 | 1.3 | 2 | 0 | 0 | 11 | 38 | 6 | 1 | 2 | 1 | 61 |
| 42 | Luke MusgraveGreen Bay Packers·#88 | 17 | 6 | 4 | 42 | 0 | 66.7% | 7.00 | 10.50 | 3 | 78 | 1.3 | 0 | 0 | 0 | 6 | 37 | 6 | 2 | 2 | 0 | 60 |
| 43 | Mo Alie-CoxIndianapolis Colts·#81 | 16 | 6 | 4 | 33 | 0 | 66.7% | 5.50 | 8.25 | 20 | 28 | 0.7 | 2 | 1 | 0 | 10 | 36 | 6 | 3 | 1 | 0 | 63 |
| 44 | John BatesWashington Commanders·#87 | 14 | 5 | 2 | 13 | 0 | 40.0% | 2.60 | 6.50 | 7 | 14 | 0.3 | 0 | 0 | 0 | 4 | 36 | 3 | 1 | 0 | 0 | 53 |
| 45 | David NjokuCleveland Browns·#85 | 12 | 4 | 4 | 33 | 1 | 100.0% | 8.25 | 8.25 | 32 | 1 | 0.0 | 1 | 1 | 1 | 6 | 36 | 2 | 0 | 1 | 0 | 55 |
| 46 | Terrance FergusonLos Angeles Rams·#18 | 12 | 7 | 3 | 27 | 0 | 42.9% | 3.86 | 9.00 | 4 | 130 | 2.6 | 0 | 0 | 0 | 6 | 35 | 7 | 1 | 1 | 0 | 50 |
| 47 | Dalton KincaidBuffalo Bills·#86 | 11 | 18 | 14 | 197 | 3 | 77.8% | 10.94 | 14.07 | 53 | 193 | 4.2 | 3 | 2 | 2 | 6 | 35 | 13 | 0 | 9 | 1 | 46 |
| 48 | Mason TaylorNew York Jets·#85 | 13 | 9 | 6 | 44 | 0 | 66.7% | 4.89 | 7.33 | 11 | 25 | 0.4 | 0 | 0 | 0 | 7 | 35 | 5 | 1 | 2 | 1 | 63 |
| 49 | Mike GesickiCincinnati Bengals·#88 | 13 | 6 | 4 | 33 | 0 | 66.7% | 5.50 | 8.25 | 5 | 30 | 1.0 | 1 | 0 | 0 | 13 | 34 | 6 | 2 | 3 | 0 | 47 |
| 50 | Noah GrayKansas City Chiefs·#83 | 16 | 5 | 2 | 30 | 0 | 40.0% | 6.00 | 15.00 | 17 | 62 | 1.1 | 0 | 0 | 0 | 1 | 33 | 5 | 0 | 1 | 0 | 59 |