| 1 | Jake FergusonDallas Cowboys·#87 | 17 | 16 | 11 | 64 | 3 | 68.8% | 4.00 | 5.82 | 23 | 72 | 0.8 | 8 | 4 | 3 | 12 | 66 | 12 | 5 | 7 | 0 | 94 |
| 2 | Trey McBrideArizona Cardinals·#85 | 17 | 27 | 17 | 197 | 4 | 63.0% | 7.30 | 11.59 | 75 | 221 | 2.2 | 9 | 5 | 4 | 28 | 64 | 23 | 4 | 13 | 0 | 102 |
| 3 | Juwan JohnsonNew Orleans Saints·#83 | 17 | 15 | 11 | 145 | 1 | 73.3% | 9.67 | 13.18 | 31 | 127 | 1.5 | 1 | 1 | 1 | 14 | 57 | 13 | 4 | 10 | 2 | 92 |
| 4 | Kyle PittsAtlanta Falcons·#8 | 17 | 20 | 12 | 163 | 1 | 60.0% | 8.15 | 13.58 | 64 | 235 | 2.9 | 2 | 1 | 1 | 16 | 55 | 17 | 1 | 12 | 0 | 92 |
| 5 | Oronde Gadsden IILos Angeles Chargers·#86 | 15 | 13 | 8 | 158 | 0 | 61.5% | 12.15 | 19.75 | 65 | 109 | 1.4 | 3 | 0 | 0 | 10 | 52 | 9 | 2 | 8 | 0 | 86 |
| 6 | Travis KelceKansas City Chiefs·#87 | 17 | 15 | 13 | 141 | 2 | 86.7% | 9.40 | 10.85 | 64 | 91 | 1.0 | 2 | 1 | 1 | 6 | 52 | 13 | 1 | 11 | 0 | 92 |
| 7 | T.J. HockensonMinnesota Vikings·#87 | 15 | 9 | 6 | 47 | 1 | 66.7% | 5.22 | 7.83 | 17 | 52 | 0.6 | 1 | 1 | 1 | 13 | 51 | 8 | 2 | 5 | 2 | 80 |
| 8 | Tyler WarrenIndianapolis Colts·#84 | 17 | 21 | 14 | 147 | 1 | 66.7% | 7.00 | 10.50 | 95 | 83 | 1.2 | 7 | 4 | 1 | 12 | 50 | 16 | 4 | 13 | 1 | 78 |
| 9 | Dalton SchultzHouston Texans·#86 | 17 | 18 | 11 | 102 | 1 | 61.1% | 5.67 | 9.27 | 39 | 100 | 1.1 | 5 | 1 | 1 | 7 | 49 | 13 | 0 | 10 | 0 | 90 |
| 10 | Theo JohnsonNew York Giants·#84 | 15 | 10 | 6 | 62 | 0 | 60.0% | 6.20 | 10.33 | 22 | 59 | 1.1 | 1 | 0 | 0 | 9 | 45 | 9 | 0 | 4 | 0 | 69 |
| 11 | Cade OttonTampa Bay Buccaneers·#88 | 16 | 16 | 12 | 106 | 0 | 75.0% | 6.62 | 8.83 | 60 | 59 | 0.9 | 2 | 0 | 0 | 12 | 43 | 10 | 1 | 7 | 0 | 79 |
| 12 | AJ BarnerSeattle Seahawks·#88 | 16 | 10 | 7 | 49 | 1 | 70.0% | 4.90 | 7.00 | 16 | 47 | 0.7 | 2 | 1 | 1 | 12 | 42 | 9 | 4 | 6 | 2 | 61 |
| 13 | Evan EngramDenver Broncos·#1 | 15 | 8 | 4 | 34 | 0 | 50.0% | 4.25 | 8.50 | 11 | 48 | 0.8 | 2 | 1 | 0 | 7 | 39 | 8 | 1 | 3 | 0 | 62 |
| 14 | Zach ErtzWashington Commanders·#86 | 13 | 16 | 13 | 133 | 3 | 81.3% | 8.31 | 10.23 | 21 | 123 | 1.8 | 3 | 3 | 3 | 9 | 39 | 15 | 3 | 11 | 0 | 70 |
| 15 | Mason TaylorNew York Jets·#85 | 13 | 11 | 6 | 38 | 1 | 54.5% | 3.45 | 6.33 | 21 | 32 | 0.5 | 2 | 1 | 1 | 14 | 39 | 8 | 3 | 5 | 1 | 73 |
| 16 | Dallas GoedertPhiladelphia Eagles·#88 | 15 | 12 | 10 | 82 | 3 | 83.3% | 6.83 | 8.20 | 52 | 34 | 0.7 | 5 | 4 | 3 | 2 | 39 | 5 | 3 | 8 | 0 | 76 |
| 17 | Hunter HenryNew England Patriots·#85 | 17 | 11 | 7 | 63 | 1 | 63.6% | 5.73 | 9.00 | 24 | 48 | 0.9 | 5 | 3 | 1 | 9 | 38 | 9 | 2 | 6 | 0 | 80 |
| 18 | Chig OkonkwoTennessee Titans·#85 | 17 | 11 | 5 | 24 | 0 | 45.5% | 2.18 | 4.80 | 12 | 23 | 0.8 | 2 | 1 | 0 | 9 | 37 | 9 | 2 | 2 | 0 | 75 |
| 19 | Colby ParkinsonLos Angeles Rams·#84 | 15 | 10 | 8 | 58 | 3 | 80.0% | 5.80 | 7.25 | 38 | 28 | 0.5 | 7 | 5 | 3 | 10 | 36 | 6 | 0 | 8 | 0 | 54 |
| 20 | Colston LovelandChicago Bears·#84 | 15 | 11 | 7 | 62 | 2 | 63.6% | 5.64 | 8.86 | 15 | 64 | 1.1 | 4 | 2 | 2 | 11 | 35 | 11 | 0 | 7 | 0 | 66 |
| 21 | Mark AndrewsBaltimore Ravens·#89 | 16 | 10 | 6 | 45 | 0 | 60.0% | 4.50 | 7.50 | 9 | 60 | 0.9 | 4 | 0 | 0 | 14 | 34 | 8 | 3 | 6 | 0 | 68 |
| 22 | Harold Fannin Jr.Cleveland Browns·#44 | 16 | 12 | 5 | 32 | 0 | 41.7% | 2.67 | 6.40 | 8 | 64 | 1.1 | 3 | 1 | 0 | 8 | 33 | 12 | 1 | 4 | 1 | 61 |
| 23 | Cole KmetChicago Bears·#85 | 16 | 5 | 3 | 29 | 0 | 60.0% | 5.80 | 9.67 | 18 | 21 | 0.3 | 1 | 0 | 0 | 9 | 33 | 5 | 2 | 2 | 0 | 52 |
| 24 | George KittleSan Francisco 49ers·#85 | 11 | 17 | 13 | 100 | 3 | 76.5% | 5.88 | 7.69 | 19 | 92 | 1.9 | 7 | 6 | 3 | 4 | 33 | 15 | 1 | 10 | 0 | 52 |
| 25 | Davis AllenLos Angeles Rams·#87 | 16 | 8 | 6 | 38 | 1 | 75.0% | 4.75 | 6.33 | 21 | 37 | 0.8 | 1 | 1 | 1 | 5 | 32 | 4 | 1 | 4 | 0 | 45 |
| 26 | Brock BowersLas Vegas Raiders·#89 | 12 | 22 | 15 | 120 | 5 | 68.2% | 5.45 | 8.00 | 47 | 106 | 2.2 | 8 | 5 | 4 | 12 | 31 | 18 | 2 | 11 | 0 | 62 |
| 27 | Brenton StrangeJacksonville Jaguars·#85 | 11 | 6 | 6 | 74 | 0 | 100.0% | 12.33 | 12.33 | 41 | 33 | 0.7 | 1 | 1 | 0 | 6 | 31 | 5 | 1 | 6 | 1 | 51 |
| 28 | Drew SampleCincinnati Bengals·#89 | 16 | 2 | 2 | 9 | 1 | 100.0% | 4.50 | 4.50 | 5 | 4 | 0.1 | 1 | 1 | 1 | 13 | 31 | 1 | 1 | 1 | 0 | 48 |
| 29 | Ja'Tavion SandersCarolina Panthers·#0 | 12 | 7 | 5 | 30 | 1 | 71.4% | 4.29 | 6.00 | 10 | 40 | 0.8 | 4 | 3 | 1 | 10 | 30 | 6 | 0 | 4 | 0 | 51 |
| 30 | Sam LaPortaDetroit Lions·#87 | 9 | 12 | 8 | 111 | 2 | 66.7% | 9.25 | 13.88 | 60 | 82 | 1.6 | 3 | 2 | 1 | 3 | 30 | 6 | 1 | 5 | 1 | 50 |
| 31 | Tommy TrembleCarolina Panthers·#82 | 15 | 10 | 7 | 55 | 0 | 70.0% | 5.50 | 7.86 | 30 | 49 | 0.9 | 2 | 1 | 0 | 2 | 30 | 9 | 1 | 4 | 0 | 52 |
| 32 | Elijah HigginsArizona Cardinals·#84 | 15 | 11 | 7 | 64 | 0 | 63.6% | 5.82 | 9.14 | 39 | 61 | 1.4 | 2 | 0 | 0 | 11 | 29 | 8 | 1 | 5 | 0 | 43 |
| 33 | Dawson KnoxBuffalo Bills·#88 | 16 | 9 | 6 | 54 | 1 | 66.7% | 6.00 | 9.00 | 36 | 26 | 0.9 | 4 | 2 | 1 | 9 | 29 | 6 | 1 | 5 | 0 | 45 |
| 34 | Pat FreiermuthPittsburgh Steelers·#88 | 17 | 10 | 5 | 47 | 0 | 50.0% | 4.70 | 9.40 | 46 | 25 | 0.5 | 1 | 0 | 0 | 6 | 28 | 4 | 0 | 4 | 0 | 57 |
| 35 | Mike GesickiCincinnati Bengals·#88 | 12 | 12 | 7 | 98 | 2 | 58.3% | 8.17 | 14.00 | 6 | 161 | 4.2 | 3 | 2 | 2 | 15 | 28 | 9 | 2 | 7 | 1 | 44 |
| 36 | Noah GrayKansas City Chiefs·#83 | 15 | 7 | 4 | 49 | 0 | 57.1% | 7.00 | 12.25 | 30 | 32 | 0.7 | 1 | 1 | 0 | 0 | 28 | 3 | 1 | 3 | 0 | 48 |
| 37 | Jake TongesSan Francisco 49ers·#88 | 7 | 9 | 7 | 63 | 1 | 77.8% | 7.00 | 9.00 | 11 | 68 | 1.7 | 1 | 1 | 1 | 6 | 27 | 7 | 2 | 6 | 0 | 41 |
| 38 | Jonnu SmithPittsburgh Steelers·#81 | 15 | 10 | 7 | 46 | 1 | 70.0% | 4.60 | 6.57 | 23 | 55 | 1.6 | 2 | 2 | 1 | 6 | 26 | 5 | 0 | 4 | 0 | 53 |
| 39 | Adam TrautmanDenver Broncos·#82 | 13 | 1 | 0 | 0 | 0 | 0.0% | 0.00 | — | 0 | 0 | 0.2 | 0 | 0 | 0 | 9 | 26 | 1 | 0 | 0 | 0 | 42 |
| 40 | Dalton KincaidBuffalo Bills·#86 | 11 | 9 | 6 | 82 | 1 | 66.7% | 9.11 | 13.67 | 49 | 89 | 2.4 | 1 | 1 | 1 | 6 | 25 | 6 | 1 | 5 | 0 | 37 |
| 41 | Daniel BellingerNew York Giants·#82 | 13 | 4 | 2 | 18 | 0 | 50.0% | 4.50 | 9.00 | 10 | 26 | 0.7 | 1 | 0 | 0 | 7 | 25 | 3 | 0 | 1 | 0 | 40 |
| 42 | Jeremy RuckertNew York Jets·#89 | 15 | 6 | 5 | 30 | 0 | 83.3% | 5.00 | 6.00 | 11 | 24 | 0.7 | 1 | 0 | 0 | 8 | 24 | 4 | 2 | 3 | 1 | 36 |
| 43 | Terrance FergusonLos Angeles Rams·#18 | 12 | 7 | 3 | 60 | 0 | 42.9% | 8.57 | 20.00 | 19 | 97 | 2.5 | 1 | 0 | 0 | 8 | 24 | 6 | 2 | 2 | 0 | 41 |
| 44 | Gunnar HelmTennessee Titans·#84 | 16 | 7 | 5 | 50 | 0 | 71.4% | 7.14 | 10.00 | 15 | 36 | 0.8 | 0 | 0 | 0 | 4 | 24 | 4 | 0 | 5 | 1 | 47 |
| 45 | Darnell WashingtonPittsburgh Steelers·#80 | 16 | 7 | 6 | 58 | 0 | 85.7% | 8.29 | 9.67 | 24 | 54 | 1.5 | 1 | 1 | 0 | 1 | 23 | 5 | 1 | 4 | 0 | 37 |
| 46 | David NjokuCleveland Browns·#85 | 11 | 3 | 1 | 8 | 0 | 33.3% | 2.67 | 8.00 | 5 | 27 | 0.6 | 1 | 1 | 0 | 8 | 23 | 2 | 1 | 1 | 1 | 49 |
| 47 | Tucker KraftGreen Bay Packers·#85 | 8 | 12 | 9 | 197 | 2 | 75.0% | 16.42 | 21.89 | 131 | 71 | 1.7 | 3 | 3 | 1 | 3 | 23 | 7 | 0 | 8 | 0 | 41 |
| 48 | Mitchell EvansCarolina Panthers·#84 | 13 | 4 | 4 | 18 | 1 | 100.0% | 4.50 | 4.50 | 14 | 4 | 0.1 | 1 | 1 | 1 | 3 | 22 | 3 | 1 | 2 | 0 | 34 |
| 49 | Isaiah LikelyBaltimore Ravens·#80 | 13 | 2 | 2 | 39 | 1 | 100.0% | 19.50 | 19.50 | 22 | 17 | 0.4 | 1 | 1 | 1 | 11 | 22 | 1 | 3 | 2 | 0 | 45 |
| 50 | Tyler HigbeeLos Angeles Rams·#89 | 10 | 6 | 3 | 35 | 0 | 50.0% | 5.83 | 11.67 | 12 | 55 | 1.9 | 2 | 2 | 0 | 8 | 21 | 5 | 3 | 2 | 0 | 29 |