| 1 | Pat FreiermuthPittsburgh Steelers·#88 | 15 | 13 | 10 | 177 | 1 | 76.9% | 13.62 | 17.70 | 85 | 122 | 2.2 | 1 | 0 | 0 | 6 | 36 | 11 | 3 | 4 | 1 | 55 |
| 2 | Dalton KincaidBuffalo Bills·#86 | 11 | 4 | 4 | 97 | 1 | 100.0% | 24.25 | 24.25 | 34 | 63 | 2.1 | 1 | 1 | 1 | 2 | 24 | 4 | 1 | 4 | 0 | 30 |
| 3 | Noah GrayKansas City Chiefs·#83 | 14 | 5 | 2 | 31 | 0 | 40.0% | 6.20 | 15.50 | 11 | 70 | 2.1 | 0 | 0 | 0 | 2 | 20 | 5 | 0 | 1 | 0 | 34 |
| 4 | Zach ErtzWashington Commanders·#86 | 13 | 13 | 10 | 125 | 0 | 76.9% | 9.62 | 12.50 | 25 | 132 | 2.0 | 0 | 0 | 0 | 7 | 37 | 11 | 1 | 4 | 0 | 65 |
| 5 | Isaiah LikelyBaltimore Ravens·#80 | 14 | 7 | 5 | 54 | 0 | 71.4% | 7.71 | 10.80 | 6 | 70 | 2.0 | 0 | 0 | 0 | 4 | 24 | 5 | 1 | 2 | 0 | 35 |
| 6 | Austin HooperNew England Patriots·#81 | 15 | 6 | 4 | 68 | 0 | 66.7% | 11.33 | 17.00 | 20 | 80 | 2.0 | 0 | 0 | 0 | 0 | 20 | 6 | 1 | 2 | 0 | 40 |
| 7 | Hunter HenryNew England Patriots·#85 | 17 | 14 | 8 | 115 | 0 | 57.1% | 8.21 | 14.38 | 49 | 113 | 2.0 | 2 | 2 | 0 | 8 | 36 | 10 | 4 | 3 | 0 | 60 |
| 8 | Tucker KraftGreen Bay Packers·#85 | 8 | 5 | 4 | 41 | 0 | 80.0% | 8.20 | 10.25 | 27 | 45 | 1.6 | 0 | 0 | 0 | 0 | 18 | 5 | 0 | 1 | 0 | 28 |
| 9 | Trey McBrideArizona Cardinals·#85 | 17 | 21 | 17 | 176 | 2 | 81.0% | 8.38 | 10.35 | 64 | 159 | 1.6 | 3 | 2 | 2 | 12 | 59 | 16 | 2 | 5 | 2 | 104 |
| 10 | Luke MusgraveGreen Bay Packers·#88 | 14 | 6 | 3 | 14 | 0 | 50.0% | 2.33 | 4.67 | -1 | 48 | 1.5 | 0 | 0 | 0 | 5 | 17 | 5 | 0 | 1 | 1 | 32 |
| 11 | Travis KelceKansas City Chiefs·#87 | 17 | 23 | 16 | 117 | 0 | 69.6% | 5.09 | 7.31 | 54 | 135 | 1.5 | 1 | 1 | 0 | 7 | 56 | 18 | 1 | 4 | 0 | 88 |
| 12 | Brock BowersLas Vegas Raiders·#89 | 11 | 13 | 9 | 94 | 0 | 69.2% | 7.23 | 10.44 | 30 | 71 | 1.5 | 2 | 2 | 0 | 7 | 39 | 12 | 2 | 4 | 0 | 58 |
| 13 | Oronde Gadsden IILos Angeles Chargers·#86 | 15 | 8 | 5 | 82 | 0 | 62.5% | 10.25 | 16.40 | 23 | 83 | 1.5 | 1 | 0 | 0 | 12 | 41 | 8 | 2 | 2 | 0 | 70 |
| 14 | Jake FergusonDallas Cowboys·#87 | 16 | 17 | 16 | 145 | 0 | 94.1% | 8.53 | 9.06 | 61 | 92 | 1.3 | 1 | 1 | 0 | 10 | 55 | 13 | 0 | 5 | 0 | 69 |
| 15 | Dalton SchultzHouston Texans·#86 | 17 | 22 | 17 | 186 | 0 | 77.3% | 8.45 | 10.94 | 105 | 107 | 1.3 | 1 | 0 | 0 | 10 | 58 | 17 | 0 | 4 | 0 | 88 |
| 16 | Harold Fannin Jr.Cleveland Browns·#44 | 15 | 26 | 17 | 122 | 0 | 65.4% | 4.69 | 7.18 | 70 | 103 | 1.2 | 1 | 1 | 0 | 16 | 53 | 17 | 2 | 3 | 0 | 83 |
| 17 | Evan EngramDenver Broncos·#1 | 16 | 17 | 12 | 105 | 0 | 70.6% | 6.18 | 8.75 | 70 | 40 | 1.2 | 4 | 3 | 0 | 7 | 44 | 10 | 1 | 4 | 0 | 59 |
| 18 | Gunnar HelmTennessee Titans·#84 | 13 | 8 | 7 | 51 | 0 | 87.5% | 6.38 | 7.29 | 23 | 44 | 1.2 | 0 | 0 | 0 | 4 | 24 | 4 | 0 | 1 | 0 | 36 |
| 19 | Ben SinnottWashington Commanders·#82 | 11 | 5 | 5 | 79 | 0 | 100.0% | 15.80 | 15.80 | 49 | 30 | 1.2 | 0 | 0 | 0 | 4 | 13 | 3 | 0 | 2 | 0 | 25 |
| 20 | T.J. HockensonMinnesota Vikings·#87 | 14 | 15 | 12 | 115 | 0 | 80.0% | 7.67 | 9.58 | 59 | 70 | 1.1 | 2 | 1 | 0 | 6 | 42 | 9 | 2 | 4 | 0 | 63 |
| 21 | Dawson KnoxBuffalo Bills·#88 | 13 | 3 | 2 | 38 | 0 | 66.7% | 12.67 | 19.00 | 7 | 53 | 1.1 | 0 | 0 | 0 | 6 | 31 | 2 | 1 | 1 | 0 | 47 |
| 22 | Cade OttonTampa Bay Buccaneers·#88 | 16 | 13 | 8 | 83 | 0 | 61.5% | 6.38 | 10.38 | 40 | 83 | 1.1 | 0 | 0 | 0 | 8 | 51 | 10 | 4 | 2 | 0 | 77 |
| 23 | Juwan JohnsonNew Orleans Saints·#83 | 17 | 14 | 11 | 133 | 0 | 78.6% | 9.50 | 12.09 | 48 | 85 | 1.1 | 1 | 0 | 0 | 10 | 56 | 12 | 4 | 4 | 0 | 86 |
| 24 | Mike GesickiCincinnati Bengals·#88 | 11 | 6 | 5 | 41 | 0 | 83.3% | 6.83 | 8.20 | 17 | 40 | 1.1 | 0 | 0 | 0 | 4 | 21 | 5 | 1 | 2 | 0 | 37 |
| 25 | Colston LovelandChicago Bears·#84 | 15 | 10 | 9 | 72 | 0 | 90.0% | 7.20 | 8.00 | 19 | 67 | 1.1 | 1 | 1 | 0 | 9 | 34 | 8 | 4 | 3 | 1 | 63 |
| 26 | Theo JohnsonNew York Giants·#84 | 15 | 9 | 7 | 64 | 0 | 77.8% | 7.11 | 9.14 | 12 | 53 | 1.1 | 2 | 0 | 0 | 8 | 37 | 7 | 1 | 2 | 0 | 65 |
| 27 | Mason TaylorNew York Jets·#85 | 13 | 12 | 7 | 64 | 0 | 58.3% | 5.33 | 9.14 | 23 | 59 | 1.0 | 0 | 0 | 0 | 9 | 32 | 10 | 1 | 2 | 0 | 62 |
| 28 | George KittleSan Francisco 49ers·#85 | 11 | 8 | 6 | 56 | 0 | 75.0% | 7.00 | 9.33 | 29 | 27 | 1.0 | 1 | 1 | 0 | 7 | 27 | 4 | 0 | 2 | 1 | 36 |
| 29 | Colby ParkinsonLos Angeles Rams·#84 | 13 | 8 | 5 | 51 | 0 | 62.5% | 6.38 | 10.20 | 43 | 37 | 1.0 | 0 | 0 | 0 | 7 | 30 | 3 | 2 | 1 | 1 | 37 |
| 30 | Jeremy RuckertNew York Jets·#89 | 15 | 7 | 6 | 39 | 0 | 85.7% | 5.57 | 6.50 | 13 | 26 | 1.0 | 0 | 0 | 0 | 5 | 22 | 4 | 1 | 0 | 0 | 33 |
| 31 | Kyle PittsAtlanta Falcons·#8 | 17 | 18 | 17 | 160 | 0 | 94.4% | 8.89 | 9.41 | 73 | 87 | 1.0 | 0 | 0 | 0 | 6 | 67 | 9 | 3 | 7 | 0 | 97 |
| 32 | Brenton StrangeJacksonville Jaguars·#85 | 12 | 10 | 7 | 70 | 0 | 70.0% | 7.00 | 10.00 | 25 | 49 | 0.9 | 2 | 1 | 0 | 4 | 32 | 6 | 1 | 3 | 0 | 53 |
| 33 | Tyler HigbeeLos Angeles Rams·#89 | 9 | 3 | 3 | 44 | 1 | 100.0% | 14.67 | 14.67 | 18 | 26 | 0.8 | 0 | 0 | 0 | 3 | 23 | 2 | 2 | 2 | 0 | 32 |
| 34 | Jonnu SmithPittsburgh Steelers·#81 | 15 | 7 | 2 | 2 | 0 | 28.6% | 0.29 | 1.00 | 4 | 48 | 0.8 | 2 | 0 | 0 | 4 | 40 | 5 | 3 | 0 | 1 | 61 |
| 35 | Greg DulcichMiami Dolphins·#85 | 9 | 7 | 5 | 78 | 0 | 71.4% | 11.14 | 15.60 | 52 | 23 | 0.7 | 1 | 1 | 0 | 5 | 22 | 3 | 1 | 2 | 0 | 31 |
| 36 | Dallas GoedertPhiladelphia Eagles·#88 | 15 | 8 | 5 | 34 | 0 | 62.5% | 4.25 | 6.80 | 10 | 53 | 0.7 | 0 | 0 | 0 | 7 | 39 | 8 | 2 | 1 | 1 | 72 |
| 37 | Jake TongesSan Francisco 49ers·#88 | 8 | 9 | 7 | 58 | 0 | 77.8% | 6.44 | 8.29 | 43 | 25 | 0.7 | 0 | 0 | 0 | 5 | 30 | 4 | 1 | 1 | 0 | 38 |
| 38 | Ja'Tavion SandersCarolina Panthers·#0 | 10 | 5 | 5 | 34 | 0 | 100.0% | 6.80 | 6.80 | 13 | 21 | 0.7 | 1 | 1 | 0 | 2 | 21 | 3 | 0 | 1 | 0 | 30 |
| 39 | Mark AndrewsBaltimore Ravens·#89 | 17 | 8 | 7 | 44 | 0 | 87.5% | 5.50 | 6.29 | 6 | 38 | 0.7 | 0 | 0 | 0 | 6 | 39 | 6 | 3 | 1 | 1 | 54 |
| 40 | Tyler WarrenIndianapolis Colts·#84 | 17 | 15 | 11 | 102 | 1 | 73.3% | 6.80 | 9.27 | 67 | 42 | 0.7 | 3 | 3 | 1 | 7 | 60 | 10 | 1 | 4 | 1 | 88 |
| 41 | Mo Alie-CoxIndianapolis Colts·#81 | 13 | 3 | 2 | 16 | 0 | 66.7% | 5.33 | 8.00 | 5 | 16 | 0.6 | 0 | 0 | 0 | 2 | 16 | 2 | 2 | 0 | 0 | 25 |
| 42 | Cole KmetChicago Bears·#85 | 16 | 5 | 2 | 27 | 0 | 40.0% | 5.40 | 13.50 | 7 | 40 | 0.6 | 0 | 0 | 0 | 5 | 39 | 4 | 4 | 1 | 0 | 62 |
| 43 | Darnell WashingtonPittsburgh Steelers·#80 | 14 | 5 | 5 | 71 | 0 | 100.0% | 14.20 | 14.20 | 50 | 21 | 0.6 | 0 | 0 | 0 | 1 | 25 | 2 | 0 | 1 | 1 | 36 |
| 44 | David NjokuCleveland Browns·#85 | 11 | 7 | 6 | 45 | 0 | 85.7% | 6.43 | 7.50 | 31 | 23 | 0.5 | 1 | 0 | 0 | 8 | 38 | 4 | 1 | 1 | 1 | 50 |
| 45 | Adam TrautmanDenver Broncos·#82 | 13 | 3 | 2 | 19 | 0 | 66.7% | 6.33 | 9.50 | 5 | 16 | 0.4 | 0 | 0 | 0 | 4 | 23 | 2 | 2 | 1 | 0 | 37 |
| 46 | Noah FantCincinnati Bengals·#86 | 13 | 5 | 4 | 23 | 0 | 80.0% | 4.60 | 5.75 | 12 | 11 | 0.3 | 0 | 0 | 0 | 3 | 24 | 1 | 0 | 0 | 0 | 32 |
| 47 | Daniel BellingerNew York Giants·#82 | 15 | 1 | 0 | 0 | 0 | 0.0% | 0.00 | — | 0 | 12 | 0.3 | 0 | 0 | 0 | 7 | 18 | 1 | 1 | 0 | 1 | 36 |
| 48 | AJ BarnerSeattle Seahawks·#88 | 15 | 8 | 5 | 38 | 0 | 62.5% | 4.75 | 7.60 | 24 | 15 | 0.3 | 0 | 0 | 0 | 4 | 31 | 3 | 2 | 0 | 0 | 47 |
| 49 | Chig OkonkwoTennessee Titans·#85 | 17 | 12 | 9 | 78 | 0 | 75.0% | 6.50 | 8.67 | 65 | 17 | 0.3 | 1 | 1 | 0 | 6 | 32 | 5 | 0 | 2 | 0 | 55 |
| 50 | Elijah HigginsArizona Cardinals·#84 | 15 | 7 | 7 | 57 | 0 | 100.0% | 8.14 | 8.14 | 42 | 15 | 0.3 | 0 | 0 | 0 | 7 | 32 | 3 | 2 | 1 | 0 | 48 |