| 1 | Andrew OgletreeIndianapolis Colts·#85 | 15 | 5 | 3 | 23 | 0 | 60.0% | 4.60 | 7.67 | 9 | 19 | 0.5 | 1 | 1 | 0 | 9 | 46 | 4 | 3 | 1 | 0 | 72 |
| 2 | Ben SimsMinnesota Vikings·#89 | 6 | 5 | 3 | 30 | 0 | 60.0% | 6.00 | 10.00 | 5 | 46 | 1.4 | 1 | 0 | 0 | 7 | 19 | 4 | 0 | 2 | 0 | 32 |
| 3 | Charlie KolarBaltimore Ravens·#88 | 17 | 12 | 8 | 124 | 1 | 66.7% | 10.33 | 15.50 | 48 | 97 | 1.0 | 2 | 1 | 1 | 9 | 58 | 9 | 6 | 7 | 0 | 94 |
| 4 | Brenton StrangeJacksonville Jaguars·#85 | 12 | 50 | 38 | 453 | 2 | 76.0% | 9.06 | 11.92 | 202 | 343 | 1.4 | 6 | 4 | 1 | 34 | 161 | 34 | 4 | 20 | 0 | 262 |
| 5 | Cade StoverHouston Texans·#87 | 9 | 13 | 10 | 61 | 0 | 76.9% | 4.69 | 6.10 | 40 | 21 | 0.4 | 3 | 3 | 0 | 9 | 48 | 11 | 1 | 2 | 0 | 66 |
| 6 | Colson YankoffWashington Commanders·#80 | 12 | 2 | 1 | 14 | 0 | 50.0% | 7.00 | 14.00 | 1 | 17 | 0.6 | 0 | 0 | 0 | 2 | 16 | 2 | 0 | 1 | 0 | 30 |
| 7 | Cole KmetChicago Bears·#85 | 16 | 37 | 25 | 302 | 2 | 67.6% | 8.16 | 12.08 | 118 | 256 | 1.2 | 4 | 3 | 1 | 28 | 181 | 26 | 12 | 13 | 0 | 305 |
| 8 | Chris ManhertzNew York Giants·#85 | 13 | 2 | 1 | 7 | 0 | 50.0% | 3.50 | 7.00 | 6 | 1 | 0.3 | 1 | 0 | 0 | 5 | 26 | 2 | 2 | 0 | 0 | 42 |
| 9 | Darren WallerMiami Dolphins·#83 | 9 | 20 | 12 | 134 | 2 | 60.0% | 6.70 | 11.17 | 44 | 176 | 1.7 | 3 | 2 | 2 | 13 | 70 | 16 | 2 | 7 | 0 | 122 |
| 10 | Grant CalcaterraPhiladelphia Eagles·#81 | 15 | 10 | 7 | 61 | 1 | 70.0% | 6.10 | 8.71 | 23 | 72 | 0.7 | 2 | 2 | 1 | 12 | 65 | 9 | 3 | 2 | 0 | 109 |
| 11 | Hunter LongJacksonville Jaguars·#84 | 9 | 11 | 7 | 45 | 0 | 63.6% | 4.09 | 6.43 | 19 | 35 | 0.3 | 1 | 0 | 0 | 14 | 70 | 6 | 2 | 0 | 0 | 113 |
| 12 | Harrison BryantHouston Texans·#88 | 11 | 4 | 1 | 2 | 0 | 25.0% | 0.50 | 2.00 | 0 | 39 | 1.0 | 0 | 0 | 0 | 3 | 22 | 3 | 1 | 0 | 0 | 51 |
| 13 | Ian ThomasLas Vegas Raiders·#80 | 14 | 12 | 12 | 109 | 0 | 100.0% | 9.08 | 9.08 | 63 | 46 | 0.4 | 0 | 0 | 0 | 18 | 67 | 9 | 2 | 4 | 0 | 115 |
| 14 | Gunnar HelmTennessee Titans·#84 | 16 | 42 | 35 | 288 | 1 | 83.3% | 6.86 | 8.23 | 136 | 192 | 1.1 | 6 | 3 | 0 | 23 | 120 | 26 | 5 | 9 | 0 | 208 |
| 15 | Eric SaubertSeattle Seahawks·#81 | 10 | 6 | 3 | 22 | 0 | 50.0% | 3.67 | 7.33 | 14 | 21 | 0.3 | 3 | 2 | 0 | 5 | 56 | 5 | 6 | 1 | 0 | 77 |
| 16 | Durham SmytheChicago Bears·#81 | 16 | 5 | 4 | 25 | 0 | 80.0% | 5.00 | 6.25 | 15 | 15 | 0.2 | 0 | 0 | 0 | 6 | 59 | 3 | 4 | 1 | 0 | 85 |
| 17 | Jackson HawesBuffalo Bills·#85 | 17 | 11 | 9 | 149 | 1 | 81.8% | 13.55 | 16.56 | 66 | 99 | 1.1 | 1 | 1 | 0 | 6 | 62 | 4 | 1 | 7 | 0 | 91 |
| 18 | Josiah DeguaraArizona Cardinals·#45 | 10 | 4 | 2 | 13 | 1 | 50.0% | 3.25 | 6.50 | 1 | 14 | 0.5 | 1 | 1 | 1 | 10 | 23 | 4 | 1 | 1 | 0 | 40 |
| 19 | Josh OliverMinnesota Vikings·#84 | 14 | 11 | 9 | 108 | 2 | 81.8% | 9.82 | 12.00 | 53 | 64 | 0.6 | 2 | 2 | 1 | 17 | 64 | 10 | 4 | 5 | 0 | 110 |
| 20 | Jack StollNew Orleans Saints·#88 | 14 | 8 | 5 | 42 | 1 | 62.5% | 5.25 | 8.40 | 17 | 23 | 0.3 | 1 | 1 | 1 | 3 | 29 | 4 | 1 | 1 | 0 | 55 |
| 21 | Josh WhyleGreen Bay Packers·#81 | 8 | 4 | 3 | 13 | 0 | 75.0% | 3.25 | 4.33 | 12 | 9 | 0.1 | 0 | 0 | 0 | 4 | 38 | 1 | 1 | 0 | 0 | 66 |
| 22 | Julian HillMiami Dolphins·#89 | 14 | 17 | 13 | 134 | 0 | 76.5% | 7.88 | 10.31 | 107 | 56 | 0.4 | 3 | 1 | 0 | 10 | 93 | 10 | 5 | 5 | 0 | 152 |
| 23 | John FitzPatrickGreen Bay Packers·#86 | 15 | 12 | 9 | 58 | 0 | 75.0% | 4.83 | 6.44 | 47 | 20 | 0.2 | 2 | 0 | 0 | 18 | 74 | 5 | 4 | 2 | 0 | 118 |
| 24 | Tanner ConnerMiami Dolphins·#48 | 9 | 13 | 9 | 91 | 0 | 69.2% | 7.00 | 10.11 | 39 | 109 | 1.2 | 2 | 1 | 0 | 4 | 55 | 10 | 4 | 3 | 0 | 89 |
| 25 | Payne DurhamTampa Bay Buccaneers·#87 | 15 | 4 | 1 | 11 | 0 | 25.0% | 2.75 | 11.00 | 11 | 11 | 0.2 | 1 | 0 | 0 | 8 | 47 | 3 | 7 | 1 | 0 | 78 |
| 26 | Shane ZylstraDetroit Lions·#84 | 5 | 3 | 2 | 16 | 0 | 66.7% | 5.33 | 8.00 | 0 | 32 | 0.4 | 0 | 0 | 0 | 3 | 49 | 3 | 0 | 0 | 0 | 79 |
| 27 | Sam LaPortaDetroit Lions·#87 | 9 | 31 | 28 | 330 | 1 | 90.3% | 10.65 | 11.79 | 188 | 151 | 0.8 | 3 | 2 | 1 | 18 | 142 | 22 | 2 | 14 | 0 | 187 |
| 28 | Ross DwelleyDetroit Lions·#82 | 6 | 3 | 2 | 7 | 0 | 66.7% | 2.33 | 3.50 | 7 | 0 | 0.0 | 1 | 1 | 0 | 0 | 22 | 3 | 0 | 0 | 0 | 29 |
| 29 | Michael MayerLas Vegas Raiders·#87 | 13 | 33 | 24 | 253 | 0 | 72.7% | 7.67 | 10.54 | 159 | 138 | 0.7 | 3 | 2 | 0 | 19 | 119 | 19 | 2 | 10 | 0 | 182 |
| 30 | Mo Alie-CoxIndianapolis Colts·#81 | 17 | 15 | 11 | 96 | 0 | 73.3% | 6.40 | 8.73 | 72 | 30 | 0.3 | 5 | 4 | 0 | 19 | 99 | 8 | 7 | 2 | 0 | 149 |
| 31 | Nate AdkinsDenver Broncos·#45 | 9 | 8 | 6 | 48 | 1 | 75.0% | 6.00 | 8.00 | 26 | 21 | 0.5 | 1 | 1 | 1 | 5 | 33 | 6 | 1 | 3 | 0 | 51 |
| 32 | Kylen GransonPhiladelphia Eagles·#83 | 14 | 5 | 5 | 31 | 0 | 100.0% | 6.20 | 6.20 | 10 | 21 | 0.3 | 1 | 1 | 0 | 7 | 38 | 3 | 0 | 1 | 0 | 68 |
| 33 | Tucker FiskLos Angeles Chargers·#42 | 10 | 1 | 1 | 7 | 0 | 100.0% | 7.00 | 7.00 | 9 | -2 | -0.0 | 0 | 0 | 0 | 4 | 27 | 0 | 0 | 0 | 0 | 50 |
| 34 | Tyler ConklinLos Angeles Chargers·#83 | 8 | 7 | 6 | 80 | 0 | 85.7% | 11.43 | 13.33 | 42 | 38 | 0.7 | 0 | 0 | 0 | 12 | 36 | 6 | 0 | 2 | 0 | 58 |
| 35 | Will DisslyLos Angeles Chargers·#89 | 9 | 15 | 10 | 90 | 0 | 66.7% | 6.00 | 9.00 | 57 | 74 | 0.9 | 1 | 1 | 0 | 14 | 46 | 11 | 0 | 4 | 0 | 79 |
| 36 | Tyler HigbeeLos Angeles Rams·#89 | 10 | 21 | 15 | 186 | 2 | 71.4% | 8.86 | 12.40 | 88 | 37 | 0.3 | 4 | 3 | 1 | 16 | 93 | 13 | 5 | 9 | 0 | 135 |
| 37 | Stone SmarttNew York Jets·#84 | 6 | 5 | 4 | 30 | 0 | 80.0% | 6.00 | 7.50 | 19 | 11 | 0.6 | 0 | 0 | 0 | 3 | 24 | 4 | 1 | 1 | 0 | 44 |
| 38 | Tip ReimanArizona Cardinals·#87 | 4 | 5 | 3 | 18 | 0 | 60.0% | 3.60 | 6.00 | 7 | 26 | 0.7 | 0 | 0 | 0 | 2 | 23 | 4 | 1 | 1 | 0 | 36 |
| 39 | Tanner HudsonCincinnati Bengals·#87 | 11 | 18 | 14 | 109 | 1 | 77.8% | 6.06 | 7.79 | 51 | 88 | 1.1 | 4 | 2 | 1 | 11 | 51 | 14 | 3 | 4 | 0 | 80 |
| 40 | Mike GesickiCincinnati Bengals·#88 | 13 | 23 | 18 | 200 | 0 | 78.3% | 8.70 | 11.11 | 56 | 171 | 1.1 | 1 | 0 | 0 | 32 | 112 | 20 | 6 | 10 | 1 | 173 |
| 41 | Luke MusgraveGreen Bay Packers·#88 | 17 | 27 | 20 | 226 | 0 | 74.1% | 8.37 | 11.30 | 54 | 254 | 1.4 | 1 | 0 | 0 | 19 | 110 | 22 | 2 | 8 | 1 | 181 |
| 42 | Noah GrayKansas City Chiefs·#83 | 16 | 24 | 14 | 114 | 0 | 58.3% | 4.75 | 8.14 | 61 | 142 | 0.7 | 0 | 0 | 0 | 12 | 124 | 20 | 2 | 4 | 1 | 229 |
| 43 | Mitchell EvansCarolina Panthers·#84 | 17 | 18 | 13 | 130 | 0 | 72.2% | 7.22 | 10.00 | 90 | 67 | 0.7 | 1 | 0 | 0 | 5 | 64 | 10 | 0 | 5 | 1 | 97 |
| 44 | Travis KelceKansas City Chiefs·#87 | 17 | 81 | 56 | 673 | 1 | 69.1% | 8.31 | 12.02 | 339 | 529 | 1.3 | 6 | 5 | 0 | 28 | 243 | 65 | 3 | 30 | 1 | 442 |
| 45 | Terrance FergusonLos Angeles Rams·#18 | 13 | 13 | 4 | 83 | 1 | 30.8% | 6.38 | 20.75 | 15 | 279 | 3.0 | 1 | 0 | 0 | 6 | 66 | 12 | 2 | 3 | 1 | 94 |
| 46 | Robert TonyanKansas City Chiefs·#85 | 14 | 1 | 1 | 1 | 0 | 100.0% | 1.00 | 1.00 | 0 | 1 | 0.0 | 0 | 0 | 0 | 1 | 15 | 0 | 0 | 0 | 1 | 38 |
| 47 | Pat FreiermuthPittsburgh Steelers·#88 | 17 | 41 | 34 | 416 | 3 | 82.9% | 10.15 | 12.24 | 206 | 251 | 1.0 | 6 | 4 | 2 | 30 | 164 | 31 | 8 | 16 | 1 | 260 |
| 48 | Quintin MorrisJacksonville Jaguars·#80 | 9 | 6 | 5 | 50 | 0 | 83.3% | 8.33 | 10.00 | 18 | 31 | 0.5 | 1 | 0 | 0 | 7 | 41 | 4 | 3 | 3 | 1 | 67 |
| 49 | Jake TongesSan Francisco 49ers·#88 | 13 | 30 | 21 | 196 | 1 | 70.0% | 6.53 | 9.33 | 107 | 130 | 0.8 | 3 | 2 | 0 | 19 | 130 | 16 | 3 | 9 | 1 | 176 |
| 50 | Johnny MundtJacksonville Jaguars·#86 | 15 | 15 | 7 | 86 | 0 | 46.7% | 5.73 | 12.29 | 61 | 68 | 0.5 | 1 | 0 | 0 | 16 | 87 | 11 | 3 | 4 | 1 | 119 |