| 1 | Adam TrautmanDenver Broncos·#82 | 17 | 8 | 7 | 47 | 0 | 87.5% | 5.88 | 6.71 | 23 | 24 | 0.2 | 0 | 0 | 0 | 14 | 88 | 7 | 5 | 2 | 0 | 152 |
| 2 | Andrew OgletreeIndianapolis Colts·#85 | 13 | 1 | 0 | 0 | 0 | 0.0% | 0.00 | — | 0 | 5 | 0.1 | 0 | 0 | 0 | 6 | 24 | 1 | 1 | 0 | 0 | 36 |
| 3 | Ben YurosekMinnesota Vikings·#85 | 9 | 3 | 2 | 14 | 0 | 66.7% | 4.67 | 7.00 | 9 | 11 | 0.3 | 0 | 0 | 0 | 2 | 25 | 3 | 1 | 1 | 0 | 32 |
| 4 | Blake WhiteheartCleveland Browns·#86 | 13 | 4 | 2 | 4 | 0 | 50.0% | 1.00 | 2.00 | 1 | 33 | 0.5 | 0 | 0 | 0 | 10 | 31 | 2 | 1 | 0 | 0 | 68 |
| 5 | Cade StoverHouston Texans·#87 | 9 | 7 | 6 | 41 | 0 | 85.7% | 5.86 | 6.83 | 27 | 14 | 0.4 | 1 | 1 | 0 | 4 | 27 | 7 | 1 | 3 | 0 | 44 |
| 6 | Brock WrightDetroit Lions·#89 | 11 | 10 | 7 | 59 | 0 | 70.0% | 5.90 | 8.43 | 53 | 2 | 0.0 | 0 | 0 | 0 | 4 | 57 | 8 | 1 | 3 | 0 | 88 |
| 7 | Brevyn Spann-FordDallas Cowboys·#89 | 14 | 7 | 4 | 42 | 1 | 57.1% | 6.00 | 10.50 | 16 | 29 | 1.2 | 2 | 2 | 1 | 5 | 31 | 4 | 0 | 2 | 0 | 56 |
| 8 | Brenton StrangeJacksonville Jaguars·#85 | 11 | 22 | 17 | 178 | 0 | 77.3% | 8.09 | 10.47 | 84 | 113 | 1.0 | 3 | 2 | 0 | 16 | 83 | 19 | 1 | 8 | 0 | 134 |
| 9 | Charlie KolarBaltimore Ravens·#88 | 16 | 10 | 6 | 90 | 2 | 60.0% | 9.00 | 15.00 | 36 | 75 | 1.1 | 3 | 2 | 2 | 9 | 39 | 9 | 5 | 6 | 0 | 65 |
| 10 | Darren WallerMiami Dolphins·#83 | 8 | 15 | 9 | 74 | 4 | 60.0% | 4.93 | 8.22 | 8 | 130 | 1.8 | 6 | 4 | 4 | 12 | 42 | 13 | 2 | 6 | 0 | 77 |
| 11 | Drew SampleCincinnati Bengals·#89 | 17 | 10 | 8 | 53 | 1 | 80.0% | 5.30 | 6.62 | 47 | 7 | 0.1 | 1 | 1 | 1 | 19 | 96 | 2 | 5 | 3 | 0 | 143 |
| 12 | Durham SmytheChicago Bears·#81 | 16 | 5 | 3 | 23 | 0 | 60.0% | 4.60 | 7.67 | 11 | 26 | 0.5 | 0 | 0 | 0 | 3 | 37 | 4 | 1 | 1 | 0 | 55 |
| 13 | Colston LovelandChicago Bears·#84 | 15 | 45 | 32 | 382 | 4 | 71.1% | 8.49 | 11.94 | 135 | 309 | 1.6 | 12 | 7 | 3 | 26 | 129 | 40 | 8 | 22 | 0 | 212 |
| 14 | Dalton KincaidBuffalo Bills·#86 | 11 | 22 | 18 | 237 | 2 | 81.8% | 10.77 | 13.17 | 145 | 112 | 1.4 | 5 | 4 | 1 | 16 | 72 | 15 | 3 | 12 | 0 | 109 |
| 15 | Cole KmetChicago Bears·#85 | 15 | 27 | 14 | 206 | 1 | 51.9% | 7.63 | 14.71 | 77 | 207 | 1.2 | 5 | 1 | 0 | 23 | 125 | 17 | 9 | 9 | 0 | 217 |
| 16 | Chris ManhertzNew York Giants·#85 | 11 | 2 | 1 | 7 | 0 | 50.0% | 3.50 | 7.00 | 6 | 1 | 0.4 | 1 | 0 | 0 | 3 | 15 | 2 | 1 | 0 | 0 | 27 |
| 17 | Jackson HawesBuffalo Bills·#85 | 17 | 11 | 10 | 135 | 2 | 90.9% | 12.27 | 13.50 | 62 | 86 | 1.1 | 2 | 2 | 1 | 5 | 56 | 5 | 0 | 8 | 0 | 81 |
| 18 | Harrison BryantHouston Texans·#88 | 11 | 2 | 0 | 0 | 0 | 0.0% | 0.00 | — | 0 | 37 | 0.9 | 0 | 0 | 0 | 6 | 16 | 2 | 0 | 0 | 0 | 40 |
| 19 | Ian ThomasLas Vegas Raiders·#80 | 14 | 8 | 8 | 63 | 0 | 100.0% | 7.88 | 7.88 | 51 | 12 | 0.2 | 0 | 0 | 0 | 9 | 46 | 6 | 4 | 2 | 0 | 68 |
| 20 | John FitzPatrickGreen Bay Packers·#86 | 13 | 5 | 4 | 26 | 1 | 80.0% | 5.20 | 6.50 | 20 | 9 | 0.1 | 2 | 1 | 1 | 11 | 42 | 2 | 2 | 2 | 0 | 73 |
| 21 | Kylen GransonPhiladelphia Eagles·#83 | 12 | 6 | 4 | 30 | 0 | 66.7% | 5.00 | 7.50 | 10 | 61 | 1.2 | 0 | 0 | 0 | 8 | 23 | 5 | 2 | 2 | 0 | 51 |
| 22 | Julian HillMiami Dolphins·#89 | 14 | 14 | 10 | 91 | 0 | 71.4% | 6.50 | 9.10 | 77 | 21 | 0.3 | 2 | 0 | 0 | 8 | 66 | 5 | 3 | 5 | 0 | 102 |
| 23 | Josh WhyleGreen Bay Packers·#81 | 7 | 3 | 3 | 7 | 1 | 100.0% | 2.33 | 2.33 | 9 | -2 | -0.0 | 1 | 1 | 1 | 9 | 32 | 1 | 2 | 1 | 0 | 49 |
| 24 | Josh OliverMinnesota Vikings·#84 | 13 | 10 | 5 | 42 | 1 | 50.0% | 4.20 | 8.40 | 22 | 26 | 0.4 | 4 | 2 | 1 | 5 | 35 | 10 | 2 | 3 | 0 | 63 |
| 25 | Foster MoreauNew Orleans Saints·#87 | 11 | 2 | 2 | 11 | 0 | 100.0% | 5.50 | 5.50 | 14 | -3 | -0.1 | 0 | 0 | 0 | 2 | 25 | 1 | 0 | 0 | 0 | 36 |
| 26 | Grant CalcaterraPhiladelphia Eagles·#81 | 13 | 6 | 4 | 24 | 0 | 66.7% | 4.00 | 6.00 | 7 | 48 | 0.9 | 0 | 0 | 0 | 9 | 34 | 5 | 6 | 1 | 0 | 56 |
| 27 | Eric SaubertSeattle Seahawks·#81 | 11 | 4 | 2 | 10 | 0 | 50.0% | 2.50 | 5.00 | 8 | 13 | 0.3 | 2 | 1 | 0 | 4 | 32 | 3 | 5 | 0 | 0 | 50 |
| 28 | Hunter LongJacksonville Jaguars·#84 | 8 | 8 | 4 | 27 | 0 | 50.0% | 3.38 | 6.75 | 12 | 24 | 0.3 | 1 | 0 | 0 | 8 | 47 | 5 | 2 | 2 | 0 | 80 |
| 29 | Evan EngramDenver Broncos·#1 | 16 | 35 | 23 | 226 | 1 | 65.7% | 6.46 | 9.83 | 147 | 139 | 0.9 | 3 | 2 | 1 | 15 | 126 | 16 | 5 | 9 | 0 | 190 |
| 30 | Mike GesickiCincinnati Bengals·#88 | 12 | 24 | 16 | 181 | 2 | 66.7% | 7.54 | 11.31 | 32 | 218 | 2.0 | 5 | 3 | 2 | 28 | 84 | 19 | 6 | 11 | 0 | 128 |
| 31 | Mason TaylorNew York Jets·#85 | 13 | 39 | 30 | 288 | 1 | 76.9% | 7.38 | 9.60 | 108 | 246 | 1.2 | 7 | 6 | 1 | 41 | 126 | 34 | 8 | 20 | 0 | 223 |
| 32 | Luke MusgraveGreen Bay Packers·#88 | 15 | 12 | 11 | 125 | 0 | 91.7% | 10.42 | 11.36 | 39 | 102 | 1.0 | 0 | 0 | 0 | 9 | 61 | 10 | 0 | 6 | 0 | 105 |
| 33 | Ross DwelleyDetroit Lions·#82 | 6 | 4 | 1 | 3 | 0 | 25.0% | 0.75 | 3.00 | 3 | 1 | 0.0 | 2 | 0 | 0 | 0 | 20 | 3 | 0 | 0 | 0 | 25 |
| 34 | Sam LaPortaDetroit Lions·#87 | 9 | 21 | 17 | 192 | 1 | 81.0% | 9.14 | 11.29 | 114 | 98 | 0.9 | 3 | 2 | 1 | 10 | 84 | 13 | 3 | 8 | 0 | 117 |
| 35 | Shane ZylstraDetroit Lions·#84 | 5 | 4 | 2 | 15 | 0 | 50.0% | 3.75 | 7.50 | 2 | 32 | 0.6 | 1 | 0 | 0 | 3 | 29 | 4 | 0 | 1 | 0 | 54 |
| 36 | Stone SmarttNew York Jets·#84 | 5 | 9 | 7 | 52 | 0 | 77.8% | 5.78 | 7.43 | 27 | 26 | 1.0 | 0 | 0 | 0 | 7 | 21 | 8 | 2 | 3 | 0 | 41 |
| 37 | Tanner ConnerMiami Dolphins·#48 | 9 | 10 | 6 | 75 | 0 | 60.0% | 7.50 | 12.50 | 34 | 72 | 1.0 | 1 | 0 | 0 | 3 | 47 | 7 | 4 | 2 | 0 | 81 |
| 38 | Tanner HudsonCincinnati Bengals·#87 | 12 | 16 | 14 | 135 | 2 | 87.5% | 8.44 | 9.64 | 55 | 97 | 1.4 | 5 | 3 | 2 | 15 | 46 | 14 | 3 | 5 | 0 | 71 |
| 39 | Payne DurhamTampa Bay Buccaneers·#87 | 14 | 1 | 0 | 0 | 0 | 0.0% | 0.00 | — | 0 | 0 | 0.1 | 0 | 0 | 0 | 9 | 26 | 0 | 5 | 0 | 0 | 48 |
| 40 | Robert TonyanKansas City Chiefs·#85 | 12 | 1 | 1 | 1 | 0 | 100.0% | 1.00 | 1.00 | 0 | 1 | 0.0 | 0 | 0 | 0 | 1 | 13 | 0 | 0 | 0 | 0 | 27 |
| 41 | Nate AdkinsDenver Broncos·#45 | 8 | 3 | 1 | 7 | 0 | 33.3% | 2.33 | 7.00 | 5 | 8 | 0.3 | 1 | 0 | 0 | 5 | 18 | 3 | 1 | 1 | 0 | 30 |
| 42 | Noah GrayKansas City Chiefs·#83 | 16 | 17 | 8 | 85 | 0 | 47.1% | 5.00 | 10.62 | 42 | 101 | 0.8 | 2 | 0 | 0 | 7 | 77 | 14 | 3 | 4 | 0 | 142 |
| 43 | Will DisslyLos Angeles Chargers·#89 | 8 | 8 | 5 | 63 | 0 | 62.5% | 7.88 | 12.60 | 57 | 36 | 0.7 | 0 | 0 | 0 | 9 | 32 | 6 | 0 | 4 | 0 | 54 |
| 44 | Tyler ConklinLos Angeles Chargers·#83 | 7 | 7 | 5 | 51 | 0 | 71.4% | 7.29 | 10.20 | 35 | 18 | 0.3 | 0 | 0 | 0 | 8 | 26 | 4 | 0 | 1 | 0 | 48 |
| 45 | Travis KelceKansas City Chiefs·#87 | 17 | 55 | 39 | 457 | 3 | 70.9% | 8.31 | 11.72 | 254 | 335 | 1.2 | 5 | 2 | 1 | 20 | 165 | 43 | 5 | 23 | 0 | 296 |
| 46 | Tucker KraftGreen Bay Packers·#85 | 8 | 25 | 19 | 252 | 4 | 76.0% | 10.08 | 13.26 | 174 | 93 | 0.9 | 7 | 6 | 3 | 8 | 63 | 17 | 0 | 12 | 0 | 99 |
| 47 | Tucker FiskLos Angeles Chargers·#42 | 9 | 3 | 1 | 7 | 0 | 33.3% | 2.33 | 7.00 | 9 | 2 | 0.7 | 0 | 0 | 0 | 4 | 19 | 0 | 0 | 0 | 0 | 34 |
| 48 | Tyler HigbeeLos Angeles Rams·#89 | 10 | 13 | 8 | 77 | 2 | 61.5% | 5.92 | 9.62 | 28 | 93 | 1.1 | 1 | 1 | 1 | 19 | 62 | 10 | 5 | 4 | 0 | 86 |
| 49 | Michael MayerLas Vegas Raiders·#87 | 11 | 19 | 16 | 196 | 0 | 84.2% | 10.32 | 12.25 | 114 | 90 | 0.8 | 1 | 1 | 0 | 6 | 75 | 12 | 3 | 11 | 0 | 114 |
| 50 | Mo Alie-CoxIndianapolis Colts·#81 | 17 | 6 | 6 | 39 | 1 | 100.0% | 6.50 | 6.50 | 24 | 15 | 0.2 | 4 | 4 | 1 | 9 | 50 | 3 | 2 | 1 | 0 | 80 |