| 1 | Andrei IosivasCincinnati Bengals·#80 | 14 | 12 | 4 | 77 | 1 | 33.3% | 6.42 | 19.25 | 18 | 92 | 1.8 | 3 | 1 | 1 | 17 | 62 | 11 | 6 | 4 | 1 | 93 |
| 2 | Ja'Marr ChaseCincinnati Bengals·#1 | 12 | 22 | 16 | 200 | 2 | 72.7% | 9.09 | 12.50 | 70 | 197 | 2.6 | 5 | 3 | 2 | 17 | 62 | 19 | 5 | 13 | 1 | 89 |
| 3 | Chris OlaveNew Orleans Saints·#12 | 13 | 26 | 18 | 206 | 2 | 69.2% | 7.92 | 11.44 | 30 | 254 | 3.7 | 2 | 1 | 1 | 13 | 61 | 24 | 2 | 11 | 0 | 100 |
| 4 | Tee HigginsCincinnati Bengals·#5 | 11 | 16 | 8 | 126 | 2 | 50.0% | 7.88 | 15.75 | 14 | 173 | 2.7 | 3 | 1 | 1 | 13 | 58 | 16 | 4 | 6 | 1 | 82 |
| 5 | Jameson WilliamsDetroit Lions·#1 | 16 | 13 | 6 | 120 | 1 | 46.1% | 9.23 | 20.00 | 37 | 153 | 1.8 | 3 | 0 | 0 | 9 | 52 | 11 | 2 | 6 | 0 | 84 |
| 6 | Amon-Ra St. BrownDetroit Lions·#14 | 13 | 23 | 15 | 202 | 1 | 65.2% | 8.78 | 13.47 | 85 | 163 | 2.5 | 4 | 2 | 1 | 8 | 48 | 19 | 2 | 10 | 0 | 78 |
| 7 | Tetairoa McMillanCarolina Panthers·#4 | 16 | 12 | 6 | 109 | 1 | 50.0% | 9.08 | 18.17 | 29 | 161 | 2.2 | 1 | 1 | 1 | 10 | 47 | 9 | 1 | 5 | 2 | 83 |
| 8 | Emeka EgbukaTampa Bay Buccaneers·#2 | 15 | 14 | 6 | 138 | 1 | 42.9% | 9.86 | 23.00 | 48 | 174 | 3.1 | 3 | 1 | 0 | 10 | 46 | 12 | 1 | 5 | 2 | 78 |
| 9 | Jalen NailorMinnesota Vikings·#1 | 15 | 12 | 7 | 79 | 2 | 58.3% | 6.58 | 11.29 | 7 | 111 | 1.6 | 5 | 2 | 2 | 12 | 46 | 11 | 4 | 6 | 0 | 74 |
| 10 | Chimere DikeTennessee Titans·#17 | 11 | 11 | 6 | 17 | 1 | 54.5% | 1.55 | 2.83 | 15 | 74 | 1.0 | 4 | 2 | 1 | 8 | 46 | 6 | 0 | 2 | 2 | 71 |
| 11 | Elic AyomanorTennessee Titans·#5 | 13 | 6 | 2 | 24 | 0 | 33.3% | 4.00 | 12.00 | 0 | 42 | 0.7 | 1 | 0 | 0 | 8 | 45 | 5 | 0 | 2 | 3 | 74 |
| 12 | Jerry JeudyCleveland Browns·#3 | 16 | 11 | 5 | 65 | 0 | 45.5% | 5.91 | 13.00 | 13 | 119 | 1.7 | 2 | 0 | 0 | 9 | 45 | 11 | 3 | 5 | 0 | 87 |
| 13 | Michael WilsonArizona Cardinals·#14 | 16 | 21 | 7 | 99 | 0 | 33.3% | 4.71 | 14.14 | 20 | 284 | 3.6 | 3 | 1 | 0 | 22 | 43 | 20 | 3 | 5 | 0 | 85 |
| 14 | Justin JeffersonMinnesota Vikings·#18 | 13 | 15 | 7 | 90 | 0 | 46.7% | 6.00 | 12.86 | 31 | 139 | 2.8 | 3 | 0 | 0 | 11 | 41 | 13 | 5 | 4 | 0 | 69 |
| 15 | Tre TuckerLas Vegas Raiders·#1 | 14 | 4 | 3 | 71 | 1 | 75.0% | 17.75 | 23.67 | 24 | 52 | 0.9 | 0 | 0 | 0 | 3 | 41 | 3 | 1 | 1 | 1 | 60 |
| 16 | Jordan AddisonMinnesota Vikings·#3 | 13 | 13 | 9 | 147 | 2 | 69.2% | 11.31 | 16.33 | 74 | 123 | 1.8 | 5 | 4 | 2 | 12 | 40 | 11 | 4 | 7 | 0 | 68 |
| 17 | Courtland SuttonDenver Broncos·#14 | 15 | 12 | 7 | 108 | 0 | 58.3% | 9.00 | 15.43 | 15 | 111 | 2.8 | 1 | 0 | 0 | 4 | 39 | 10 | 2 | 6 | 0 | 68 |
| 18 | Sterling ShepardTampa Bay Buccaneers·#17 | 11 | 4 | 4 | 52 | 1 | 100.0% | 13.00 | 13.00 | 27 | 25 | 0.4 | 1 | 1 | 1 | 8 | 38 | 1 | 1 | 4 | 1 | 61 |
| 19 | Wan'Dale RobinsonNew York Giants·#17 | 15 | 20 | 6 | 104 | 2 | 30.0% | 5.20 | 17.33 | 5 | 286 | 3.6 | 4 | 1 | 1 | 14 | 38 | 16 | 1 | 5 | 1 | 86 |
| 20 | DK MetcalfPittsburgh Steelers·#4 | 12 | 8 | 5 | 46 | 0 | 62.5% | 5.75 | 9.20 | 7 | 52 | 1.1 | 0 | 0 | 0 | 10 | 37 | 8 | 2 | 4 | 1 | 58 |
| 21 | Calvin Austin IIIPittsburgh Steelers·#19 | 10 | 13 | 9 | 111 | 2 | 69.2% | 8.54 | 12.33 | 9 | 140 | 3.0 | 1 | 1 | 1 | 9 | 36 | 11 | 2 | 5 | 0 | 55 |
| 22 | Isaac TeSlaaDetroit Lions·#18 | 11 | 7 | 3 | 41 | 1 | 42.9% | 5.86 | 13.67 | 25 | 58 | 1.0 | 5 | 2 | 1 | 6 | 36 | 6 | 1 | 3 | 0 | 58 |
| 23 | Van JeffersonTennessee Titans·#11 | 9 | 8 | 7 | 67 | 1 | 87.5% | 8.38 | 9.57 | 19 | 48 | 1.1 | 2 | 2 | 1 | 4 | 35 | 8 | 0 | 7 | 1 | 51 |
| 24 | Malik WashingtonMiami Dolphins·#6 | 13 | 7 | 5 | 31 | 0 | 71.4% | 4.43 | 6.20 | 32 | -1 | 0.6 | 1 | 1 | 0 | 4 | 34 | 3 | 3 | 1 | 0 | 60 |
| 25 | Michael PittmanIndianapolis Colts·#11 | 11 | 15 | 10 | 85 | 0 | 66.7% | 5.67 | 8.50 | 30 | 163 | 2.9 | 2 | 1 | 0 | 11 | 33 | 13 | 1 | 5 | 1 | 57 |
| 26 | Khalil ShakirBuffalo Bills·#10 | 11 | 11 | 6 | 92 | 0 | 54.5% | 8.36 | 15.33 | 21 | 56 | 1.0 | 3 | 1 | 0 | 6 | 33 | 7 | 2 | 4 | 0 | 57 |
| 27 | George PickensDallas Cowboys·#3 | 13 | 12 | 9 | 152 | 2 | 75.0% | 12.67 | 16.89 | 70 | 133 | 2.3 | 3 | 2 | 1 | 7 | 32 | 11 | 2 | 8 | 2 | 57 |
| 28 | Isaiah WilliamsNew York Jets·#18 | 7 | 8 | 5 | 31 | 0 | 62.5% | 3.88 | 6.20 | 13 | 18 | 0.4 | 0 | 0 | 0 | 13 | 32 | 5 | 3 | 3 | 0 | 61 |
| 29 | Zay FlowersBaltimore Ravens·#4 | 13 | 9 | 7 | 117 | 1 | 77.8% | 13.00 | 16.71 | 67 | 83 | 1.7 | 2 | 1 | 0 | 3 | 32 | 6 | 4 | 3 | 2 | 50 |
| 30 | DJ MooreChicago Bears·#2 | 15 | 6 | 3 | 80 | 0 | 50.0% | 13.33 | 26.67 | 25 | 62 | 1.4 | 1 | 0 | 0 | 10 | 31 | 5 | 2 | 2 | 1 | 68 |
| 31 | Troy FranklinDenver Broncos·#11 | 15 | 11 | 6 | 92 | 0 | 54.5% | 8.36 | 15.33 | 58 | 125 | 2.7 | 1 | 1 | 0 | 5 | 30 | 8 | 2 | 3 | 0 | 53 |
| 32 | Mason TiptonNew Orleans Saints·#15 | 6 | 3 | 1 | 9 | 0 | 33.3% | 3.00 | 9.00 | 0 | 55 | 1.3 | 1 | 0 | 0 | 4 | 29 | 3 | 2 | 1 | 0 | 43 |
| 33 | Nick Westbrook-IkhineMiami Dolphins·#18 | 10 | 6 | 2 | 14 | 0 | 33.3% | 2.33 | 7.00 | 0 | 28 | 0.8 | 0 | 0 | 0 | 3 | 29 | 6 | 3 | 2 | 0 | 45 |
| 34 | Jalen CokerCarolina Panthers·#18 | 10 | 8 | 7 | 83 | 1 | 87.5% | 10.38 | 11.86 | -1 | 82 | 1.7 | 2 | 1 | 1 | 3 | 29 | 5 | 1 | 5 | 2 | 48 |
| 35 | Arian SmithNew York Jets·#82 | 12 | 4 | 1 | 14 | 0 | 25.0% | 3.50 | 14.00 | 10 | 31 | 1.4 | 0 | 0 | 0 | 10 | 29 | 4 | 3 | 1 | 0 | 49 |
| 36 | Adonai MitchellNew York Jets·#15 | 7 | 17 | 6 | 76 | 0 | 35.3% | 4.47 | 12.67 | 11 | 185 | 4.1 | 4 | 1 | 0 | 13 | 29 | 16 | 2 | 3 | 0 | 62 |
| 37 | Devaughn VeleNew Orleans Saints·#14 | 7 | 15 | 8 | 90 | 1 | 53.3% | 6.00 | 11.25 | 7 | 140 | 2.8 | 3 | 1 | 1 | 5 | 28 | 10 | 2 | 6 | 0 | 52 |
| 38 | Xavier WorthyKansas City Chiefs·#1 | 11 | 7 | 4 | 80 | 0 | 57.1% | 11.43 | 20.00 | 25 | 55 | 2.1 | 0 | 0 | 0 | 4 | 28 | 5 | 3 | 3 | 0 | 50 |
| 39 | Josh DownsIndianapolis Colts·#2 | 9 | 6 | 5 | 41 | 1 | 83.3% | 6.83 | 8.20 | 7 | 33 | 0.6 | 2 | 2 | 1 | 10 | 27 | 4 | 1 | 4 | 1 | 52 |
| 40 | Xavier LegetteCarolina Panthers·#17 | 14 | 12 | 5 | 78 | 0 | 41.7% | 6.50 | 15.60 | 3 | 118 | 2.2 | 2 | 0 | 0 | 7 | 27 | 10 | 0 | 3 | 2 | 57 |
| 41 | Kendrick BourneSan Francisco 49ers·#84 | 13 | 10 | 7 | 71 | 0 | 70.0% | 7.10 | 10.14 | 24 | 83 | 2.1 | 0 | 0 | 0 | 6 | 27 | 6 | 0 | 4 | 1 | 45 |
| 42 | Rashid ShaheedNew Orleans Saints·#22 | 7 | 11 | 8 | 65 | 0 | 72.7% | 5.91 | 8.12 | 9 | 83 | 2.6 | 0 | 0 | 0 | 7 | 27 | 10 | 0 | 4 | 0 | 44 |
| 43 | Jaylen WaddleMiami Dolphins·#17 | 10 | 10 | 4 | 79 | 1 | 40.0% | 7.90 | 19.75 | 19 | 117 | 3.6 | 0 | 0 | 0 | 2 | 27 | 9 | 1 | 3 | 0 | 42 |
| 44 | A.J. BrownPhiladelphia Eagles·#11 | 11 | 14 | 10 | 178 | 1 | 71.4% | 12.71 | 17.80 | 50 | 161 | 3.8 | 2 | 1 | 1 | 9 | 27 | 14 | 3 | 8 | 0 | 51 |
| 45 | Allen LazardNew York Jets·#10 | 10 | 5 | 2 | 13 | 1 | 40.0% | 2.60 | 6.50 | 6 | 63 | 1.3 | 2 | 1 | 1 | 10 | 26 | 2 | 2 | 2 | 0 | 47 |
| 46 | DeVonta SmithPhiladelphia Eagles·#6 | 11 | 8 | 4 | 40 | 1 | 50.0% | 5.00 | 10.00 | 5 | 70 | 1.4 | 2 | 1 | 1 | 9 | 26 | 7 | 3 | 3 | 0 | 51 |
| 47 | Jahan DotsonPhiladelphia Eagles·#2 | 11 | 7 | 4 | 56 | 0 | 57.1% | 8.00 | 14.00 | 11 | 84 | 2.1 | 0 | 0 | 0 | 8 | 26 | 5 | 0 | 3 | 0 | 52 |
| 48 | Brandin CooksNew Orleans Saints·#18 | 8 | 4 | 4 | 26 | 0 | 100.0% | 6.50 | 6.50 | 2 | 24 | 0.5 | 0 | 0 | 0 | 6 | 25 | 4 | 0 | 3 | 0 | 45 |
| 49 | Cedric TillmanCleveland Browns·#19 | 9 | 3 | 1 | 2 | 0 | 33.3% | 0.67 | 2.00 | 1 | 6 | 0.4 | 1 | 1 | 0 | 7 | 25 | 3 | 1 | 0 | 0 | 45 |
| 50 | Cooper KuppSeattle Seahawks·#10 | 10 | 10 | 5 | 53 | 0 | 50.0% | 5.30 | 10.60 | 20 | 47 | 1.7 | 2 | 1 | 0 | 2 | 25 | 7 | 1 | 1 | 1 | 45 |