| 1 | Nick MullensJacksonville Jaguars·#14 | 5 | 3 | 3 | 100.0% | 19 | 6.33 | 0 | 0 | 0.0% | 0 | 4 | 1.3 | 1.80 | 1.80 | 0 | 0 | 0 | 27 |
| 2 | Malik WillisGreen Bay Packers·#2 | 4 | 36 | 30 | 83.3% | 422 | 11.72 | 3 | 0 | 0.0% | 3 | 354 | 10.1 | 2.53 | 2.53 | 2 | 0 | 2 | 95 |
| 3 | Tyler HuntleyBaltimore Ravens·#5 | 5 | 68 | 52 | 76.5% | 426 | 6.26 | 2 | 0 | 0.0% | 8 | 429 | 6.4 | 2.32 | 2.32 | 0 | 1 | 1 | 189 |
| 4 | Mason RudolphPittsburgh Steelers·#2 | 5 | 52 | 38 | 73.1% | 310 | 5.96 | 2 | 2 | 3.9% | 2 | 272 | 5.2 | 2.54 | 2.54 | 0 | 3 | 1 | 106 |
| 5 | Drake MayeNew England Patriots·#10 | 17 | 495 | 354 | 71.5% | 4,396 | 8.88 | 31 | 8 | 1.6% | 49 | 4,500 | 9.1 | 2.82 | 2.82 | 16 | 19 | 8 | 1,006 |
| 6 | Mitchell TrubiskyBuffalo Bills·#11 | 4 | 35 | 25 | 71.4% | 315 | 9.00 | 4 | 0 | 0.0% | 0 | 255 | 6.9 | 2.71 | 2.71 | 0 | 1 | 0 | 96 |
| 7 | Joshua DobbsNew England Patriots·#11 | 4 | 10 | 7 | 70.0% | 65 | 6.50 | 0 | 0 | 0.0% | 0 | 119 | 11.9 | 2.76 | 2.76 | 0 | 0 | 0 | 40 |
| 8 | Mac JonesSan Francisco 49ers·#10 | 11 | 288 | 201 | 69.8% | 2,153 | 7.48 | 13 | 5 | 1.7% | 18 | 2,119 | 7.3 | 2.54 | 2.54 | 4 | 6 | 3 | 527 |
| 9 | Josh AllenBuffalo Bills·#17 | 17 | 460 | 319 | 69.3% | 3,670 | 7.98 | 25 | 10 | 2.2% | 41 | 3,359 | 7.2 | 2.78 | 2.78 | 9 | 14 | 7 | 993 |
| 10 | Brock PurdySan Francisco 49ers·#13 | 9 | 285 | 197 | 69.1% | 2,169 | 7.61 | 20 | 10 | 3.5% | 12 | 2,172 | 7.5 | 3.02 | 3.02 | 3 | 15 | 3 | 558 |
| 11 | Daniel JonesIndianapolis Colts·#17 | 13 | 383 | 261 | 68.2% | 3,103 | 8.10 | 19 | 7 | 1.8% | 22 | 3,089 | 7.9 | 2.58 | 2.59 | 8 | 9 | 4 | 716 |
| 12 | Sam DarnoldSeattle Seahawks·#14 | 17 | 475 | 323 | 68.0% | 4,052 | 8.53 | 25 | 13 | 2.7% | 28 | 3,740 | 7.8 | 2.73 | 2.74 | 13 | 23 | 9 | 966 |
| 13 | Jared GoffDetroit Lions·#16 | 17 | 578 | 393 | 68.0% | 4,564 | 7.90 | 34 | 8 | 1.4% | 39 | 3,715 | 6.4 | 2.57 | 2.57 | 8 | 30 | 7 | 1,042 |
| 14 | Spencer RattlerNew Orleans Saints·#2 | 9 | 256 | 174 | 68.0% | 1,586 | 6.20 | 8 | 4 | 1.6% | 18 | 2,021 | 7.9 | 2.45 | 2.45 | 3 | 6 | 5 | 460 |
| 15 | Tua TagovailoaMiami Dolphins·#1 | 14 | 384 | 260 | 67.7% | 2,662 | 6.93 | 20 | 15 | 3.9% | 31 | 2,608 | 6.8 | 2.52 | 2.52 | 6 | 13 | 3 | 751 |
| 16 | Tyler ShoughNew Orleans Saints·#6 | 11 | 327 | 221 | 67.6% | 2,384 | 7.29 | 10 | 6 | 1.8% | 31 | 2,708 | 8.3 | 2.53 | 2.53 | 9 | 11 | 5 | 582 |
| 17 | Andy DaltonCarolina Panthers·#14 | 4 | 37 | 25 | 67.6% | 293 | 7.92 | 1 | 1 | 2.7% | 8 | 348 | 9.4 | 2.39 | 2.39 | 1 | 1 | 1 | 93 |
| 18 | Geno SmithLas Vegas Raiders·#7 | 15 | 447 | 302 | 67.6% | 3,027 | 6.77 | 19 | 17 | 3.8% | 56 | 2,762 | 6.1 | 2.70 | 2.70 | 7 | 11 | 2 | 823 |
| 19 | Dak PrescottDallas Cowboys·#4 | 17 | 599 | 404 | 67.5% | 4,558 | 7.61 | 30 | 9 | 1.5% | 34 | 4,802 | 8.0 | 2.70 | 2.70 | 10 | 15 | 7 | 1,070 |
| 20 | Kyler MurrayArizona Cardinals·#1 | 5 | 164 | 110 | 67.1% | 962 | 5.87 | 6 | 3 | 1.8% | 16 | 941 | 5.8 | 2.54 | 2.54 | 2 | 4 | 3 | 298 |
| 21 | Joe BurrowCincinnati Bengals·#9 | 8 | 259 | 173 | 66.8% | 1,809 | 6.98 | 17 | 5 | 1.9% | 18 | 1,868 | 7.2 | 2.57 | 2.57 | 12 | 7 | 2 | 460 |
| 22 | Drew LockSeattle Seahawks·#2 | 5 | 3 | 2 | 66.7% | 15 | 5.00 | 0 | 0 | 0.0% | 0 | 5 | 1.7 | 2.83 | 2.83 | 0 | 0 | 1 | 37 |
| 23 | Justin HerbertLos Angeles Chargers·#10 | 16 | 512 | 340 | 66.4% | 3,727 | 7.28 | 26 | 11 | 2.1% | 54 | 4,022 | 7.9 | 2.74 | 2.74 | 15 | 14 | 4 | 995 |
| 24 | Jordan LoveGreen Bay Packers·#10 | 15 | 439 | 291 | 66.3% | 3,385 | 7.71 | 23 | 5 | 1.1% | 21 | 3,863 | 8.8 | 2.73 | 2.73 | 10 | 29 | 4 | 855 |
| 25 | Quinn EwersMiami Dolphins·#14 | 4 | 83 | 55 | 66.3% | 622 | 7.49 | 3 | 3 | 3.6% | 8 | 683 | 8.3 | 2.60 | 2.60 | 2 | 0 | 2 | 175 |
| 26 | Aaron RodgersPittsburgh Steelers·#8 | 16 | 496 | 327 | 65.9% | 3,324 | 6.70 | 24 | 7 | 1.4% | 31 | 3,018 | 6.0 | 2.48 | 2.48 | 10 | 21 | 4 | 867 |
| 27 | Cooper RushBaltimore Ravens·#15 | 4 | 52 | 34 | 65.4% | 303 | 5.83 | 0 | 4 | 7.7% | 1 | 335 | 6.4 | 2.49 | 2.49 | 0 | 2 | 2 | 106 |
| 28 | Carson WentzMinnesota Vikings·#11 | 5 | 169 | 110 | 65.1% | 1,218 | 7.21 | 6 | 5 | 3.0% | 21 | 1,288 | 7.6 | 2.60 | 2.60 | 2 | 5 | 2 | 286 |
| 29 | Jacoby BrissettArizona Cardinals·#7 | 14 | 486 | 315 | 64.8% | 3,368 | 6.93 | 23 | 8 | 1.6% | 43 | 3,697 | 7.6 | 2.81 | 2.81 | 7 | 24 | 6 | 771 |
| 30 | Matthew StaffordLos Angeles Rams·#9 | 17 | 599 | 388 | 64.8% | 4,707 | 7.86 | 46 | 7 | 1.2% | 23 | 5,426 | 9.1 | 2.66 | 2.66 | 17 | 16 | 7 | 1,067 |
| 31 | Jalen HurtsPhiladelphia Eagles·#1 | 16 | 454 | 294 | 64.8% | 3,224 | 7.10 | 25 | 6 | 1.3% | 33 | 4,072 | 8.9 | 2.84 | 2.84 | 10 | 23 | 6 | 925 |
| 32 | C.J. StroudHouston Texans·#7 | 14 | 423 | 273 | 64.5% | 3,041 | 7.19 | 19 | 8 | 1.9% | 24 | 3,398 | 8.0 | 2.69 | 2.69 | 10 | 19 | 2 | 806 |
| 33 | Max BrosmerMinnesota Vikings·#12 | 7 | 73 | 47 | 64.4% | 328 | 4.49 | 0 | 4 | 5.5% | 14 | 311 | 4.4 | 2.53 | 2.51 | 1 | 2 | 3 | 170 |
| 34 | Jake BrowningCincinnati Bengals·#6 | 5 | 126 | 81 | 64.3% | 771 | 6.12 | 6 | 8 | 6.3% | 9 | 959 | 7.7 | 2.62 | 2.62 | 1 | 6 | 3 | 197 |
| 35 | Chris OladokunKansas City Chiefs·#19 | 3 | 55 | 35 | 63.6% | 235 | 4.27 | 1 | 0 | 0.0% | 8 | 277 | 5.0 | 2.74 | 2.74 | 0 | 2 | 2 | 105 |
| 36 | Bryce YoungCarolina Panthers·#9 | 16 | 478 | 304 | 63.6% | 3,013 | 6.30 | 23 | 11 | 2.3% | 28 | 3,102 | 6.5 | 2.68 | 2.68 | 6 | 27 | 8 | 919 |
| 37 | Bo NixDenver Broncos·#10 | 17 | 612 | 388 | 63.4% | 3,939 | 6.44 | 25 | 11 | 1.8% | 25 | 4,488 | 7.3 | 2.73 | 2.73 | 17 | 25 | 4 | 1,095 |
| 38 | Jaxson DartNew York Giants·#6 | 14 | 341 | 216 | 63.3% | 2,274 | 6.67 | 15 | 5 | 1.5% | 36 | 2,783 | 8.1 | 2.69 | 2.70 | 7 | 10 | 5 | 734 |
| 39 | Baker MayfieldTampa Bay Buccaneers·#6 | 17 | 543 | 343 | 63.2% | 3,697 | 6.81 | 26 | 11 | 2.0% | 37 | 4,406 | 8.0 | 2.68 | 2.68 | 8 | 13 | 5 | 1,039 |
| 40 | Lamar JacksonBaltimore Ravens·#38 | 13 | 304 | 192 | 63.2% | 2,551 | 8.39 | 21 | 7 | 2.3% | 36 | 2,658 | 8.7 | 2.82 | 2.82 | 6 | 13 | 8 | 670 |
| 41 | Philip RiversIndianapolis Colts·#17 | 3 | 92 | 58 | 63.0% | 544 | 5.91 | 4 | 3 | 3.3% | 5 | 717 | 7.8 | 2.30 | 2.30 | 3 | 2 | 0 | 166 |
| 42 | Joe FlaccoCincinnati Bengals·#16 | 10 | 300 | 189 | 63.0% | 1,958 | 6.53 | 14 | 6 | 2.0% | 12 | 2,153 | 7.1 | 2.60 | 2.60 | 7 | 17 | 2 | 470 |
| 43 | Josh JohnsonWashington Commanders·#14 | 5 | 54 | 34 | 63.0% | 372 | 6.89 | 1 | 2 | 3.7% | 2 | 313 | 5.8 | 2.89 | 2.89 | 1 | 2 | 1 | 128 |
| 44 | Patrick MahomesKansas City Chiefs·#15 | 14 | 503 | 315 | 62.6% | 3,591 | 7.14 | 22 | 10 | 2.0% | 34 | 4,051 | 8.0 | 2.66 | 2.66 | 17 | 25 | 1 | 886 |
| 45 | Joe Milton IIIDallas Cowboys·#10 | 4 | 24 | 15 | 62.5% | 183 | 7.62 | 1 | 2 | 8.3% | 0 | 256 | 10.8 | 2.52 | 2.52 | 1 | 1 | 1 | 48 |
| 46 | Justin FieldsNew York Jets·#7 | 9 | 205 | 128 | 62.4% | 1,254 | 6.12 | 7 | 1 | 49.0% | 27 | 1,389 | 6.6 | 2.76 | 2.78 | 2 | 8 | 5 | 486 |
| 47 | Kirk CousinsAtlanta Falcons·#18 | 10 | 269 | 166 | 61.7% | 1,721 | 6.40 | 10 | 5 | 1.9% | 13 | 1,870 | 6.9 | 2.58 | 2.58 | 2 | 12 | 5 | 525 |
| 48 | Marcus MariotaWashington Commanders·#8 | 11 | 227 | 139 | 61.2% | 1,697 | 7.48 | 10 | 7 | 3.1% | 16 | 2,295 | 10.0 | 2.75 | 2.75 | 3 | 12 | 4 | 486 |
| 49 | Kenny PickettLas Vegas Raiders·#15 | 6 | 46 | 28 | 60.9% | 188 | 4.09 | 1 | 2 | 4.3% | 8 | 259 | 5.8 | 2.64 | 2.64 | 0 | 0 | 1 | 78 |
| 50 | Trevor LawrenceJacksonville Jaguars·#16 | 17 | 562 | 341 | 60.7% | 4,007 | 7.13 | 29 | 12 | 2.1% | 42 | 4,880 | 8.7 | 2.71 | 2.72 | 14 | 13 | 5 | 1,048 |