| 1 | Baker MayfieldTampa Bay Buccaneers·#6 | 16 | 57 | 38 | 66.7% | 419 | 7.35 | 1 | 0 | 0.0% | 3 | 502 | 8.8 | 2.46 | 2.46 | 2 | 21 | 0 | 1 | 1 | 1 | 62 |
| 2 | C.J. StroudHouston Texans·#7 | 12 | 28 | 18 | 64.3% | 151 | 5.39 | 0 | 0 | 0.0% | 1 | 178 | 6.4 | 2.11 | 2.11 | 2 | 14 | 0 | 0 | 1 | 1 | 31 |
| 3 | Dak PrescottDallas Cowboys·#4 | 16 | 76 | 55 | 72.4% | 679 | 8.93 | 5 | 0 | 0.0% | 3 | 755 | 9.8 | 2.62 | 2.62 | 1 | 12 | 0 | 4 | 5 | 0 | 81 |
| 4 | Jayden DanielsWashington Commanders·#5 | 7 | 37 | 23 | 62.2% | 281 | 7.59 | 3 | 0 | 0.0% | 3 | 373 | 10.1 | 2.89 | 2.89 | 9 | 43 | 0 | 2 | 2 | 0 | 49 |
| 5 | Joe FlaccoCincinnati Bengals·#16 | 7 | 32 | 18 | 56.3% | 259 | 8.09 | 1 | 0 | 0.0% | 3 | 327 | 10.2 | 2.75 | 2.75 | 0 | 0 | 0 | 0 | 2 | 0 | 35 |
| 6 | Jaxson DartNew York Giants·#6 | 12 | 43 | 33 | 76.7% | 372 | 8.65 | 3 | 0 | 0.0% | 7 | 387 | 9.0 | 2.57 | 2.62 | 7 | 59 | 1 | 2 | 0 | 0 | 59 |
| 7 | Matthew StaffordLos Angeles Rams·#9 | 13 | 44 | 28 | 63.6% | 445 | 10.11 | 2 | 0 | 0.0% | 1 | 505 | 11.5 | 2.38 | 2.38 | 0 | 0 | 0 | 0 | 1 | 0 | 45 |
| 8 | Jordan LoveGreen Bay Packers·#10 | 14 | 26 | 19 | 73.1% | 197 | 7.58 | 0 | 0 | 0.0% | 3 | 185 | 7.1 | 2.47 | 2.47 | 2 | 9 | 0 | 0 | 3 | 0 | 31 |
| 9 | Spencer RattlerNew Orleans Saints·#2 | 8 | 23 | 12 | 52.2% | 101 | 4.39 | 0 | 0 | 0.0% | 3 | 181 | 7.9 | 2.42 | 2.42 | 2 | 18 | 0 | 0 | 1 | 0 | 28 |
| 10 | Trevor LawrenceJacksonville Jaguars·#16 | 15 | 45 | 25 | 55.6% | 229 | 5.09 | 5 | 0 | 0.0% | 3 | 423 | 9.2 | 2.56 | 2.64 | 4 | 36 | 0 | 0 | 1 | 0 | 53 |
| 11 | Aaron RodgersPittsburgh Steelers·#8 | 16 | 107 | 64 | 59.8% | 694 | 6.49 | 2 | 1 | 93.0% | 8 | 878 | 8.1 | 2.45 | 2.45 | 1 | 7 | 0 | 4 | 4 | 0 | 117 |
| 12 | Bryce YoungCarolina Panthers·#9 | 16 | 82 | 48 | 58.5% | 443 | 5.40 | 4 | 1 | 1.2% | 3 | 654 | 8.0 | 2.41 | 2.41 | 7 | 44 | 0 | 0 | 4 | 2 | 93 |
| 13 | Bo NixDenver Broncos·#10 | 16 | 69 | 46 | 66.7% | 481 | 6.97 | 4 | 1 | 1.4% | 3 | 549 | 8.0 | 2.55 | 2.55 | 5 | 22 | 0 | 2 | 3 | 0 | 77 |
| 14 | Josh AllenBuffalo Bills·#17 | 16 | 61 | 40 | 65.6% | 486 | 7.97 | 5 | 1 | 1.6% | 10 | 436 | 7.0 | 2.74 | 2.74 | 13 | 84 | 2 | 2 | 3 | 1 | 87 |
| 15 | Jalen HurtsPhiladelphia Eagles·#1 | 15 | 48 | 32 | 66.7% | 304 | 6.33 | 3 | 1 | 2.1% | 2 | 436 | 8.7 | 2.55 | 2.55 | 12 | 102 | 1 | 0 | 1 | 3 | 65 |
| 16 | Patrick MahomesKansas City Chiefs·#15 | 14 | 40 | 27 | 67.5% | 251 | 6.28 | 1 | 1 | 2.5% | 0 | 188 | 4.7 | 2.15 | 2.15 | 5 | 49 | 1 | 1 | 2 | 0 | 45 |
| 17 | Jacoby BrissettArizona Cardinals·#7 | 12 | 37 | 23 | 62.2% | 203 | 5.49 | 1 | 1 | 2.7% | 3 | 278 | 7.5 | 2.44 | 2.44 | 2 | 7 | 0 | 0 | 1 | 0 | 42 |
| 18 | Drake MayeNew England Patriots·#10 | 12 | 36 | 29 | 80.6% | 299 | 8.31 | 1 | 1 | 2.8% | 1 | 313 | 8.5 | 2.23 | 2.23 | 7 | 47 | 1 | 1 | 1 | 0 | 44 |
| 19 | Sam DarnoldSeattle Seahawks·#14 | 17 | 68 | 44 | 64.7% | 563 | 8.28 | 3 | 2 | 2.9% | 4 | 500 | 7.3 | 2.38 | 2.38 | 5 | 23 | 0 | 2 | 1 | 2 | 81 |
| 20 | Tyler ShoughNew Orleans Saints·#6 | 10 | 34 | 26 | 76.5% | 245 | 7.21 | 1 | 1 | 2.9% | 6 | 198 | 5.8 | 2.15 | 2.17 | 5 | 14 | 0 | 2 | 1 | 0 | 46 |
| 21 | Mac JonesSan Francisco 49ers·#10 | 8 | 31 | 19 | 61.3% | 164 | 5.29 | 1 | 1 | 3.2% | 3 | 202 | 6.5 | 2.22 | 2.22 | 0 | 0 | 0 | 0 | 0 | 0 | 34 |
| 22 | Marcus MariotaWashington Commanders·#8 | 7 | 23 | 15 | 65.2% | 160 | 6.96 | 0 | 1 | 4.3% | 1 | 257 | 11.2 | 2.56 | 2.56 | 4 | 32 | 0 | 0 | 1 | 0 | 30 |
| 23 | Cam WardTennessee Titans·#1 | 16 | 46 | 30 | 65.2% | 307 | 6.67 | 0 | 2 | 4.3% | 7 | 335 | 7.3 | 2.62 | 2.62 | 1 | 11 | 0 | 0 | 0 | 2 | 54 |
| 24 | Geno SmithLas Vegas Raiders·#7 | 11 | 23 | 18 | 78.3% | 203 | 8.83 | 1 | 1 | 4.3% | 2 | 116 | 5.0 | 2.50 | 2.50 | 1 | 1 | 0 | 1 | 2 | 0 | 26 |
| 25 | Shedeur SandersCleveland Browns·#12 | 8 | 22 | 11 | 50.0% | 157 | 7.14 | 1 | 1 | 4.5% | 3 | 223 | 10.1 | 2.86 | 2.86 | 2 | 18 | 0 | 0 | 0 | 0 | 27 |
| 26 | Jared GoffDetroit Lions·#16 | 12 | 22 | 13 | 59.1% | 93 | 4.23 | 0 | 1 | 4.5% | 2 | 119 | 5.4 | 2.11 | 2.11 | 0 | 0 | 0 | 0 | 0 | 0 | 25 |
| 27 | Caleb WilliamsChicago Bears·#18 | 16 | 43 | 23 | 53.5% | 274 | 6.37 | 2 | 2 | 4.7% | 1 | 469 | 10.9 | 2.83 | 2.83 | 5 | 36 | 0 | 1 | 4 | 0 | 49 |
| 28 | Justin HerbertLos Angeles Chargers·#10 | 15 | 35 | 28 | 80.0% | 343 | 9.80 | 3 | 2 | 5.7% | 3 | 247 | 7.1 | 2.60 | 2.60 | 5 | 34 | 0 | 2 | 2 | 0 | 44 |
| 29 | Tua TagovailoaMiami Dolphins·#1 | 13 | 43 | 21 | 48.8% | 211 | 4.91 | 0 | 3 | 7.0% | 3 | 401 | 9.3 | 2.43 | 2.43 | 1 | 6 | 0 | 0 | 1 | 0 | 51 |