| 1 | Trey McBrideArizona Cardinals·#85 | 17 | 72 | 53 | 507 | 1 | 73.6% | 7.04 | 9.57 | 273 | 410 | 1.6 | 9 | 6 | 1 | 32 | 167 | 50 | 9 | 18 | 1 | 271 |
| 2 | Tyler WarrenIndianapolis Colts·#84 | 17 | 49 | 34 | 387 | 2 | 69.4% | 7.90 | 11.38 | 237 | 269 | 1.3 | 9 | 4 | 2 | 29 | 126 | 43 | 7 | 16 | 2 | 200 |
| 3 | Travis KelceKansas City Chiefs·#87 | 17 | 37 | 25 | 366 | 1 | 67.6% | 9.89 | 14.64 | 205 | 247 | 1.3 | 3 | 3 | 0 | 8 | 106 | 29 | 1 | 15 | 0 | 205 |
| 4 | Brock BowersLas Vegas Raiders·#89 | 12 | 33 | 26 | 347 | 1 | 78.8% | 10.52 | 13.35 | 158 | 211 | 1.6 | 4 | 1 | 1 | 11 | 106 | 31 | 3 | 14 | 1 | 157 |
| 5 | Kyle PittsAtlanta Falcons·#8 | 17 | 37 | 27 | 347 | 3 | 73.0% | 9.38 | 12.85 | 148 | 282 | 1.5 | 6 | 5 | 3 | 21 | 128 | 30 | 4 | 17 | 2 | 198 |
| 6 | Hunter HenryNew England Patriots·#85 | 17 | 29 | 22 | 327 | 4 | 75.9% | 11.28 | 14.86 | 169 | 183 | 1.4 | 5 | 4 | 3 | 13 | 129 | 22 | 11 | 16 | 3 | 184 |
| 7 | AJ BarnerSeattle Seahawks·#88 | 17 | 31 | 24 | 286 | 5 | 77.4% | 9.23 | 11.92 | 154 | 185 | 1.0 | 8 | 6 | 4 | 12 | 125 | 27 | 4 | 12 | 2 | 188 |
| 8 | Juwan JohnsonNew Orleans Saints·#83 | 17 | 37 | 27 | 279 | 1 | 73.0% | 7.54 | 10.33 | 131 | 199 | 1.6 | 3 | 3 | 1 | 18 | 116 | 33 | 1 | 11 | 5 | 187 |
| 9 | George KittleSan Francisco 49ers·#85 | 11 | 25 | 22 | 279 | 1 | 88.0% | 11.16 | 12.68 | 132 | 173 | 1.7 | 0 | 0 | 0 | 15 | 78 | 19 | 1 | 13 | 1 | 114 |
| 10 | Colston LovelandChicago Bears·#84 | 16 | 31 | 18 | 270 | 3 | 58.1% | 8.71 | 15.00 | 115 | 278 | 2.0 | 5 | 4 | 1 | 18 | 95 | 28 | 6 | 10 | 0 | 163 |
| 11 | Oronde Gadsden IILos Angeles Chargers·#86 | 15 | 22 | 18 | 260 | 0 | 81.8% | 11.82 | 14.44 | 78 | 225 | 2.0 | 3 | 1 | 0 | 8 | 68 | 19 | 0 | 9 | 2 | 113 |
| 12 | Colby ParkinsonLos Angeles Rams·#84 | 15 | 30 | 26 | 260 | 4 | 86.7% | 8.67 | 10.00 | 172 | 114 | 0.7 | 12 | 9 | 2 | 13 | 115 | 16 | 4 | 11 | 1 | 158 |
| 13 | Harold Fannin Jr.Cleveland Browns·#44 | 16 | 29 | 23 | 259 | 2 | 79.3% | 8.93 | 11.26 | 133 | 156 | 0.9 | 3 | 2 | 2 | 15 | 95 | 19 | 3 | 11 | 2 | 161 |
| 14 | Dallas GoedertPhiladelphia Eagles·#88 | 15 | 34 | 25 | 250 | 5 | 73.5% | 7.35 | 10.00 | 100 | 175 | 1.4 | 5 | 5 | 4 | 16 | 101 | 21 | 4 | 12 | 1 | 160 |
| 15 | Brenton StrangeJacksonville Jaguars·#85 | 12 | 23 | 19 | 242 | 2 | 82.6% | 10.52 | 12.74 | 105 | 152 | 1.3 | 4 | 3 | 1 | 18 | 76 | 17 | 1 | 12 | 0 | 118 |
| 16 | Evan EngramDenver Broncos·#1 | 16 | 27 | 21 | 221 | 1 | 77.8% | 8.19 | 10.52 | 160 | 76 | 0.6 | 3 | 2 | 1 | 13 | 92 | 10 | 4 | 6 | 0 | 124 |
| 17 | Noah FantCincinnati Bengals·#86 | 15 | 27 | 23 | 221 | 1 | 85.2% | 8.19 | 9.61 | 136 | 85 | 1.0 | 0 | 0 | 0 | 13 | 73 | 16 | 4 | 9 | 3 | 105 |
| 18 | Dawson KnoxBuffalo Bills·#88 | 17 | 20 | 17 | 220 | 1 | 85.0% | 11.00 | 12.94 | 110 | 116 | 1.1 | 1 | 1 | 1 | 9 | 72 | 16 | 2 | 9 | 2 | 112 |
| 19 | Dalton SchultzHouston Texans·#86 | 17 | 35 | 28 | 217 | 1 | 80.0% | 6.20 | 7.75 | 105 | 153 | 1.2 | 3 | 2 | 1 | 18 | 107 | 29 | 5 | 8 | 1 | 167 |
| 20 | Jake FergusonDallas Cowboys·#87 | 17 | 40 | 31 | 215 | 4 | 77.5% | 5.38 | 6.94 | 142 | 112 | 0.8 | 9 | 6 | 3 | 16 | 122 | 24 | 6 | 11 | 0 | 174 |
| 21 | Cade OttonTampa Bay Buccaneers·#88 | 16 | 23 | 18 | 204 | 1 | 78.3% | 8.87 | 11.33 | 105 | 132 | 0.8 | 4 | 3 | 1 | 13 | 124 | 17 | 4 | 9 | 2 | 179 |
| 22 | Dalton KincaidBuffalo Bills·#86 | 11 | 18 | 15 | 203 | 1 | 83.3% | 11.28 | 13.53 | 75 | 161 | 2.7 | 3 | 2 | 0 | 11 | 43 | 14 | 2 | 9 | 1 | 67 |
| 23 | Cole KmetChicago Bears·#85 | 16 | 25 | 19 | 200 | 1 | 76.0% | 8.00 | 10.53 | 76 | 162 | 1.3 | 4 | 3 | 1 | 15 | 110 | 18 | 9 | 9 | 0 | 179 |
| 24 | Chig OkonkwoTennessee Titans·#85 | 17 | 32 | 24 | 197 | 0 | 75.0% | 6.16 | 8.21 | 133 | 89 | 0.8 | 2 | 0 | 0 | 17 | 96 | 21 | 5 | 8 | 3 | 153 |
| 25 | Sam LaPortaDetroit Lions·#87 | 9 | 15 | 14 | 192 | 0 | 93.3% | 12.80 | 13.71 | 124 | 69 | 0.7 | 1 | 0 | 0 | 5 | 74 | 11 | 1 | 7 | 0 | 96 |
| 26 | Mark AndrewsBaltimore Ravens·#89 | 17 | 24 | 18 | 186 | 1 | 75.0% | 7.75 | 10.33 | 54 | 204 | 1.8 | 3 | 3 | 1 | 16 | 77 | 19 | 1 | 9 | 3 | 114 |
| 27 | Mason TaylorNew York Jets·#85 | 13 | 29 | 21 | 179 | 1 | 72.4% | 6.17 | 8.52 | 60 | 167 | 1.2 | 4 | 4 | 1 | 17 | 87 | 21 | 5 | 9 | 1 | 145 |
| 28 | Gunnar HelmTennessee Titans·#84 | 16 | 25 | 22 | 178 | 2 | 88.0% | 7.12 | 8.09 | 81 | 98 | 1.1 | 4 | 3 | 1 | 10 | 64 | 17 | 4 | 8 | 0 | 101 |
| 29 | T.J. HockensonMinnesota Vikings·#87 | 15 | 21 | 19 | 177 | 1 | 90.5% | 8.43 | 9.32 | 88 | 103 | 0.7 | 3 | 3 | 1 | 16 | 90 | 11 | 2 | 8 | 1 | 148 |
| 30 | Theo JohnsonNew York Giants·#84 | 15 | 24 | 15 | 172 | 2 | 62.5% | 7.17 | 11.47 | 78 | 181 | 1.0 | 5 | 3 | 2 | 12 | 112 | 16 | 4 | 9 | 3 | 178 |
| 31 | Tucker KraftGreen Bay Packers·#85 | 8 | 15 | 12 | 168 | 3 | 80.0% | 11.20 | 14.00 | 133 | 38 | 0.5 | 6 | 4 | 3 | 5 | 64 | 12 | 1 | 7 | 1 | 90 |
| 32 | Michael MayerLas Vegas Raiders·#87 | 12 | 16 | 14 | 163 | 0 | 87.5% | 10.19 | 11.64 | 103 | 91 | 0.9 | 1 | 1 | 0 | 12 | 68 | 11 | 1 | 9 | 0 | 98 |
| 33 | Daniel BellingerNew York Giants·#82 | 16 | 12 | 9 | 157 | 1 | 75.0% | 13.08 | 17.44 | 47 | 148 | 1.4 | 2 | 2 | 0 | 13 | 65 | 11 | 2 | 6 | 1 | 108 |
| 34 | Austin HooperNew England Patriots·#81 | 16 | 13 | 11 | 141 | 1 | 84.6% | 10.85 | 12.82 | 53 | 94 | 0.9 | 3 | 2 | 1 | 7 | 71 | 8 | 4 | 6 | 2 | 109 |
| 35 | Darnell WashingtonPittsburgh Steelers·#80 | 16 | 19 | 11 | 134 | 0 | 57.9% | 7.05 | 12.18 | 91 | 96 | 0.9 | 3 | 3 | 0 | 8 | 80 | 14 | 2 | 5 | 1 | 121 |
| 36 | Davis AllenLos Angeles Rams·#87 | 17 | 14 | 11 | 132 | 2 | 78.6% | 9.43 | 12.00 | 93 | 72 | 0.6 | 2 | 2 | 2 | 6 | 85 | 9 | 3 | 6 | 2 | 116 |
| 37 | Adam TrautmanDenver Broncos·#82 | 17 | 13 | 12 | 124 | 0 | 92.3% | 9.54 | 10.33 | 68 | 60 | 0.5 | 0 | 0 | 0 | 10 | 82 | 10 | 0 | 6 | 0 | 133 |
| 38 | Pat FreiermuthPittsburgh Steelers·#88 | 17 | 16 | 14 | 121 | 0 | 87.5% | 7.56 | 8.64 | 79 | 42 | 0.4 | 3 | 2 | 0 | 13 | 73 | 9 | 3 | 5 | 0 | 118 |
| 39 | David NjokuCleveland Browns·#85 | 12 | 19 | 13 | 116 | 1 | 68.4% | 6.11 | 8.92 | 47 | 118 | 1.1 | 2 | 2 | 1 | 11 | 64 | 13 | 3 | 3 | 1 | 103 |
| 40 | Jackson HawesBuffalo Bills·#85 | 17 | 8 | 7 | 116 | 2 | 87.5% | 14.50 | 16.57 | 47 | 72 | 1.1 | 1 | 1 | 1 | 5 | 45 | 3 | 1 | 6 | 0 | 65 |
| 41 | Mitchell EvansCarolina Panthers·#84 | 17 | 13 | 11 | 111 | 1 | 84.6% | 8.54 | 10.09 | 74 | 45 | 0.7 | 3 | 1 | 1 | 2 | 41 | 8 | 1 | 5 | 1 | 63 |
| 42 | Luke MusgraveGreen Bay Packers·#88 | 17 | 12 | 8 | 111 | 0 | 66.7% | 9.25 | 13.88 | 33 | 127 | 1.4 | 1 | 0 | 0 | 8 | 56 | 10 | 2 | 4 | 0 | 93 |
| 43 | Zach ErtzWashington Commanders·#86 | 13 | 17 | 12 | 109 | 1 | 70.6% | 6.41 | 9.08 | 60 | 113 | 0.9 | 1 | 1 | 1 | 9 | 64 | 14 | 1 | 4 | 1 | 127 |
| 44 | Darren WallerMiami Dolphins·#83 | 8 | 11 | 7 | 109 | 2 | 63.6% | 9.91 | 15.57 | 24 | 144 | 2.6 | 3 | 2 | 2 | 3 | 37 | 10 | 1 | 6 | 0 | 60 |
| 45 | Elijah ArroyoSeattle Seahawks·#18 | 13 | 10 | 5 | 101 | 1 | 50.0% | 10.10 | 20.20 | 43 | 108 | 2.1 | 1 | 0 | 0 | 6 | 41 | 8 | 0 | 4 | 0 | 60 |
| 46 | Mike GesickiCincinnati Bengals·#88 | 12 | 12 | 8 | 99 | 0 | 66.7% | 8.25 | 12.38 | 33 | 80 | 1.1 | 2 | 0 | 0 | 13 | 50 | 10 | 3 | 4 | 1 | 78 |
| 47 | Elijah HigginsArizona Cardinals·#84 | 16 | 11 | 8 | 95 | 0 | 72.7% | 8.64 | 11.88 | 74 | 36 | 0.3 | 1 | 0 | 0 | 20 | 73 | 2 | 6 | 5 | 1 | 127 |
| 48 | Josh OliverMinnesota Vikings·#84 | 14 | 8 | 7 | 90 | 3 | 87.5% | 11.25 | 12.86 | 45 | 49 | 0.7 | 4 | 4 | 2 | 12 | 44 | 7 | 3 | 4 | 0 | 74 |
| 49 | Tyler HigbeeLos Angeles Rams·#89 | 10 | 10 | 7 | 90 | 1 | 70.0% | 9.00 | 12.86 | 51 | 55 | 0.8 | 3 | 3 | 1 | 8 | 44 | 5 | 1 | 4 | 0 | 67 |
| 50 | Jake TongesSan Francisco 49ers·#88 | 11 | 16 | 12 | 89 | 4 | 75.0% | 5.56 | 7.42 | 53 | 63 | 0.7 | 3 | 3 | 3 | 8 | 68 | 11 | 1 | 7 | 1 | 97 |