| 1 | Ja'Marr ChaseCincinnati Bengals·#1 | 16 | 81 | 57 | 614 | 7 | 70.4% | 7.58 | 10.77 | 308 | 535 | 1.8 | 22 | 13 | 7 | 67 | 218 | 61 | 17 | 36 | 1 | 323 |
| 2 | Michael WilsonArizona Cardinals·#14 | 17 | 57 | 38 | 465 | 7 | 66.7% | 8.16 | 12.24 | 90 | 593 | 2.1 | 17 | 8 | 4 | 56 | 192 | 55 | 14 | 25 | 1 | 317 |
| 3 | Andrei IosivasCincinnati Bengals·#80 | 17 | 28 | 14 | 191 | 2 | 50.0% | 6.82 | 13.64 | 46 | 222 | 1.0 | 7 | 2 | 1 | 60 | 171 | 21 | 14 | 10 | 0 | 259 |
| 4 | DJ MooreChicago Bears·#2 | 17 | 43 | 23 | 319 | 6 | 53.5% | 7.42 | 13.87 | 112 | 314 | 1.6 | 11 | 6 | 3 | 33 | 158 | 26 | 12 | 15 | 0 | 298 |
| 5 | Michael PittmanIndianapolis Colts·#11 | 17 | 49 | 34 | 335 | 7 | 69.4% | 6.84 | 9.85 | 83 | 344 | 1.3 | 18 | 8 | 5 | 39 | 159 | 42 | 11 | 22 | 2 | 256 |
| 6 | Zay FlowersBaltimore Ravens·#4 | 17 | 48 | 35 | 479 | 4 | 72.9% | 9.98 | 13.69 | 199 | 430 | 1.9 | 12 | 7 | 1 | 26 | 127 | 31 | 11 | 20 | 2 | 226 |
| 7 | Stefon DiggsNew England Patriots·#8 | 17 | 45 | 38 | 413 | 4 | 84.4% | 9.18 | 10.87 | 171 | 290 | 1.7 | 12 | 9 | 4 | 19 | 115 | 37 | 11 | 24 | 1 | 188 |
| 8 | Puka NacuaLos Angeles Rams·#12 | 16 | 76 | 57 | 781 | 10 | 75.0% | 10.28 | 13.70 | 278 | 749 | 3.3 | 17 | 14 | 5 | 36 | 147 | 60 | 10 | 39 | 3 | 231 |
| 9 | Tee HigginsCincinnati Bengals·#5 | 15 | 60 | 33 | 530 | 11 | 55.0% | 8.83 | 16.06 | 113 | 658 | 3.3 | 16 | 10 | 4 | 44 | 166 | 56 | 10 | 27 | 1 | 246 |
| 10 | DK MetcalfPittsburgh Steelers·#4 | 15 | 43 | 26 | 267 | 5 | 60.5% | 6.21 | 10.27 | 138 | 310 | 1.4 | 13 | 8 | 3 | 27 | 139 | 35 | 10 | 16 | 3 | 266 |
| 11 | Alec PierceIndianapolis Colts·#14 | 15 | 28 | 14 | 238 | 5 | 50.0% | 8.50 | 17.00 | 28 | 399 | 1.9 | 9 | 4 | 4 | 41 | 133 | 28 | 9 | 12 | 2 | 229 |
| 12 | Justin JeffersonMinnesota Vikings·#18 | 17 | 62 | 30 | 319 | 2 | 48.4% | 5.15 | 10.63 | 130 | 538 | 2.5 | 19 | 5 | 2 | 41 | 138 | 49 | 9 | 18 | 4 | 259 |
| 13 | Davante AdamsLos Angeles Rams·#17 | 14 | 59 | 28 | 325 | 14 | 47.5% | 5.51 | 11.61 | 35 | 636 | 3.2 | 32 | 13 | 12 | 41 | 133 | 52 | 9 | 26 | 4 | 210 |
| 14 | Marvin Harrison Jr.Arizona Cardinals·#18 | 11 | 34 | 18 | 236 | 4 | 52.9% | 6.94 | 13.11 | 44 | 433 | 2.5 | 11 | 6 | 4 | 31 | 102 | 33 | 9 | 14 | 0 | 174 |
| 15 | DeVonta SmithPhiladelphia Eagles·#6 | 17 | 45 | 28 | 313 | 3 | 62.2% | 6.96 | 11.18 | 90 | 417 | 2.0 | 12 | 7 | 2 | 21 | 138 | 36 | 8 | 18 | 4 | 255 |
| 16 | Kayshon BoutteNew England Patriots·#9 | 14 | 15 | 12 | 248 | 6 | 80.0% | 16.53 | 20.67 | 10 | 267 | 1.7 | 3 | 2 | 2 | 18 | 99 | 15 | 8 | 9 | 2 | 171 |
| 17 | George PickensDallas Cowboys·#3 | 17 | 72 | 45 | 713 | 9 | 62.5% | 9.90 | 15.84 | 259 | 679 | 2.7 | 24 | 11 | 4 | 41 | 181 | 66 | 8 | 36 | 2 | 287 |
| 18 | Chris OlaveNew Orleans Saints·#12 | 16 | 82 | 51 | 501 | 8 | 62.2% | 6.11 | 9.82 | 103 | 613 | 3.0 | 15 | 7 | 5 | 31 | 177 | 71 | 8 | 24 | 5 | 309 |
| 19 | Rashod BatemanBaltimore Ravens·#7 | 13 | 20 | 13 | 132 | 2 | 65.0% | 6.60 | 10.15 | 20 | 155 | 1.1 | 9 | 5 | 2 | 15 | 89 | 16 | 7 | 9 | 1 | 135 |
| 20 | Jalen NailorMinnesota Vikings·#1 | 17 | 28 | 17 | 230 | 4 | 60.7% | 8.21 | 13.53 | 40 | 274 | 1.4 | 13 | 6 | 4 | 29 | 108 | 23 | 7 | 13 | 2 | 197 |
| 21 | Jameson WilliamsDetroit Lions·#1 | 17 | 53 | 34 | 490 | 7 | 64.2% | 9.25 | 14.41 | 174 | 538 | 1.8 | 9 | 3 | 1 | 24 | 199 | 44 | 7 | 24 | 2 | 301 |
| 22 | Jordan AddisonMinnesota Vikings·#3 | 14 | 37 | 18 | 225 | 3 | 48.6% | 6.08 | 12.50 | 19 | 438 | 2.2 | 13 | 7 | 3 | 33 | 113 | 32 | 7 | 14 | 3 | 209 |
| 23 | KaVontae TurpinDallas Cowboys·#9 | 15 | 13 | 9 | 61 | 1 | 69.2% | 4.69 | 6.78 | 48 | 47 | 0.3 | 5 | 3 | 1 | 19 | 82 | 9 | 7 | 3 | 2 | 140 |
| 24 | Amon-Ra St. BrownDetroit Lions·#14 | 16 | 83 | 52 | 550 | 11 | 62.6% | 6.63 | 10.58 | 240 | 581 | 2.3 | 33 | 20 | 10 | 23 | 182 | 72 | 7 | 30 | 2 | 278 |
| 25 | A.J. BrownPhiladelphia Eagles·#11 | 15 | 52 | 39 | 467 | 7 | 75.0% | 8.98 | 11.97 | 123 | 477 | 2.3 | 13 | 9 | 3 | 19 | 128 | 47 | 6 | 22 | 4 | 230 |
| 26 | Calvin Austin IIIPittsburgh Steelers·#19 | 14 | 27 | 15 | 178 | 3 | 55.6% | 6.59 | 11.87 | 59 | 205 | 2.0 | 4 | 3 | 2 | 13 | 82 | 19 | 6 | 8 | 1 | 155 |
| 27 | Courtland SuttonDenver Broncos·#14 | 17 | 58 | 32 | 436 | 6 | 55.2% | 7.52 | 13.62 | 114 | 526 | 2.5 | 20 | 7 | 4 | 38 | 165 | 52 | 6 | 21 | 0 | 264 |
| 28 | Josh DownsIndianapolis Colts·#2 | 16 | 43 | 30 | 273 | 4 | 69.8% | 6.35 | 9.10 | 69 | 266 | 1.4 | 15 | 10 | 4 | 33 | 111 | 43 | 6 | 22 | 2 | 193 |
| 29 | Jordan WhittingtonLos Angeles Rams·#88 | 16 | 13 | 9 | 97 | 0 | 69.2% | 7.46 | 10.78 | 47 | 75 | 0.6 | 1 | 1 | 0 | 23 | 83 | 10 | 6 | 4 | 3 | 128 |
| 30 | Wan'Dale RobinsonNew York Giants·#17 | 16 | 47 | 28 | 289 | 4 | 59.6% | 6.15 | 10.32 | 110 | 362 | 1.6 | 14 | 4 | 1 | 31 | 126 | 32 | 6 | 11 | 2 | 244 |
| 31 | Jaylen WaddleMiami Dolphins·#17 | 16 | 37 | 28 | 429 | 6 | 75.7% | 11.59 | 15.32 | 124 | 349 | 2.5 | 11 | 8 | 3 | 17 | 114 | 36 | 6 | 24 | 0 | 173 |
| 32 | Malik WashingtonMiami Dolphins·#6 | 17 | 31 | 25 | 166 | 3 | 80.7% | 5.35 | 6.64 | 111 | 68 | 0.7 | 11 | 10 | 3 | 15 | 99 | 17 | 6 | 10 | 1 | 181 |
| 33 | Jahan DotsonPhiladelphia Eagles·#2 | 17 | 16 | 7 | 92 | 1 | 43.8% | 5.75 | 13.14 | 11 | 129 | 1.1 | 5 | 0 | 0 | 20 | 112 | 13 | 6 | 4 | 4 | 207 |
| 34 | Tre TuckerLas Vegas Raiders·#1 | 17 | 39 | 24 | 257 | 4 | 61.5% | 6.59 | 10.71 | 122 | 300 | 1.4 | 10 | 6 | 3 | 23 | 144 | 29 | 5 | 14 | 1 | 238 |
| 35 | Jauan JenningsSan Francisco 49ers·#15 | 15 | 53 | 29 | 323 | 9 | 54.7% | 6.09 | 11.14 | 97 | 344 | 1.9 | 22 | 11 | 7 | 40 | 153 | 50 | 5 | 19 | 3 | 228 |
| 36 | Xavier WorthyKansas City Chiefs·#1 | 13 | 25 | 13 | 144 | 1 | 52.0% | 5.76 | 11.08 | 66 | 265 | 1.3 | 6 | 4 | 1 | 16 | 115 | 22 | 5 | 7 | 0 | 211 |
| 37 | Tetairoa McMillanCarolina Panthers·#4 | 17 | 60 | 31 | 458 | 7 | 51.7% | 7.63 | 14.77 | 112 | 613 | 2.5 | 15 | 10 | 4 | 34 | 168 | 56 | 5 | 29 | 2 | 283 |
| 38 | Kendrick BourneSan Francisco 49ers·#84 | 16 | 26 | 19 | 219 | 0 | 73.1% | 8.42 | 11.53 | 49 | 257 | 1.5 | 2 | 1 | 0 | 29 | 120 | 23 | 5 | 13 | 2 | 176 |
| 39 | Troy FranklinDenver Broncos·#11 | 17 | 48 | 32 | 316 | 6 | 66.7% | 6.58 | 9.88 | 126 | 308 | 1.8 | 21 | 14 | 4 | 26 | 135 | 33 | 5 | 18 | 0 | 204 |
| 40 | Romeo DoubsGreen Bay Packers·#87 | 16 | 49 | 31 | 311 | 6 | 63.3% | 6.35 | 10.03 | 85 | 416 | 1.9 | 18 | 10 | 5 | 34 | 135 | 42 | 5 | 20 | 3 | 246 |
| 41 | Rome OdunzeChicago Bears·#15 | 12 | 45 | 25 | 340 | 6 | 55.6% | 7.56 | 13.60 | 124 | 436 | 2.4 | 13 | 5 | 3 | 19 | 106 | 37 | 5 | 22 | 1 | 206 |
| 42 | Ricky PearsallSan Francisco 49ers·#1 | 9 | 20 | 11 | 138 | 0 | 55.0% | 6.90 | 12.55 | 12 | 276 | 2.0 | 4 | 1 | 0 | 27 | 92 | 18 | 5 | 9 | 1 | 144 |
| 43 | Olamide ZaccheausChicago Bears·#14 | 16 | 33 | 18 | 125 | 2 | 54.5% | 3.79 | 6.94 | 64 | 156 | 1.0 | 13 | 7 | 2 | 16 | 97 | 17 | 5 | 7 | 0 | 193 |
| 44 | Drake LondonAtlanta Falcons·#5 | 12 | 56 | 33 | 375 | 7 | 58.9% | 6.70 | 11.36 | 121 | 428 | 2.8 | 16 | 9 | 7 | 31 | 110 | 54 | 5 | 23 | 1 | 179 |
| 45 | Deebo Samuel Sr.Washington Commanders·#1 | 16 | 55 | 41 | 445 | 5 | 74.5% | 8.09 | 10.85 | 281 | 286 | 1.0 | 12 | 9 | 4 | 34 | 120 | 29 | 5 | 20 | 2 | 281 |
| 46 | DeAndre HopkinsBaltimore Ravens·#10 | 17 | 22 | 13 | 213 | 2 | 59.1% | 9.68 | 16.38 | 35 | 314 | 3.3 | 3 | 0 | 0 | 15 | 54 | 19 | 5 | 8 | 1 | 100 |
| 47 | CeeDee LambDallas Cowboys·#88 | 14 | 54 | 28 | 308 | 2 | 51.9% | 5.70 | 11.00 | 58 | 537 | 2.6 | 17 | 8 | 2 | 25 | 133 | 50 | 5 | 18 | 1 | 214 |
| 48 | Brandin CooksNew Orleans Saints·#18 | 10 | 16 | 13 | 104 | 0 | 81.3% | 6.50 | 8.00 | 34 | 99 | 0.6 | 1 | 0 | 0 | 20 | 104 | 13 | 5 | 7 | 2 | 160 |
| 49 | Christian WatsonGreen Bay Packers·#9 | 10 | 19 | 10 | 183 | 5 | 52.6% | 9.63 | 18.30 | 53 | 255 | 1.9 | 6 | 3 | 2 | 17 | 74 | 18 | 4 | 7 | 1 | 137 |
| 50 | Darius SlaytonNew York Giants·#18 | 14 | 26 | 12 | 182 | 1 | 46.1% | 7.00 | 15.17 | 75 | 283 | 1.6 | 8 | 1 | 0 | 18 | 100 | 19 | 4 | 7 | 3 | 194 |