| 1 | Davante AdamsLos Angeles Rams·#17 | 14 | 33 | 15 | 94 | 8 | 45.5% | 2.85 | 6.27 | 9 | 269 | 3.8 | 17 | 8 | 8 | 16 | 46 | 28 | 3 | 15 | 0 | 74 |
| 2 | DK MetcalfPittsburgh Steelers·#4 | 15 | 16 | 10 | 88 | 2 | 62.5% | 5.50 | 8.80 | 32 | 104 | 2.2 | 7 | 3 | 2 | 9 | 29 | 11 | 4 | 9 | 1 | 62 |
| 3 | Keon ColemanBuffalo Bills·#0 | 13 | 9 | 7 | 38 | 3 | 77.8% | 4.22 | 5.43 | 10 | 39 | 1.0 | 7 | 5 | 3 | 5 | 27 | 6 | 1 | 7 | 0 | 39 |
| 4 | Courtland SuttonDenver Broncos·#14 | 16 | 15 | 9 | 180 | 2 | 60.0% | 12.00 | 20.00 | 54 | 181 | 2.8 | 6 | 2 | 1 | 5 | 33 | 13 | 2 | 8 | 0 | 67 |
| 5 | CeeDee LambDallas Cowboys·#88 | 13 | 23 | 12 | 169 | 0 | 52.2% | 7.35 | 14.08 | 48 | 219 | 3.7 | 6 | 2 | 0 | 10 | 37 | 21 | 3 | 12 | 0 | 67 |
| 6 | George PickensDallas Cowboys·#3 | 17 | 18 | 14 | 238 | 4 | 77.8% | 13.22 | 17.00 | 66 | 181 | 2.3 | 5 | 2 | 2 | 12 | 47 | 16 | 4 | 14 | 0 | 79 |
| 7 | Troy FranklinDenver Broncos·#11 | 16 | 12 | 9 | 79 | 2 | 75.0% | 6.58 | 8.78 | 45 | 38 | 0.9 | 5 | 3 | 2 | 4 | 29 | 8 | 2 | 8 | 0 | 57 |
| 8 | Tee HigginsCincinnati Bengals·#5 | 15 | 13 | 7 | 89 | 4 | 53.9% | 6.85 | 12.71 | 9 | 113 | 2.8 | 5 | 3 | 2 | 10 | 39 | 13 | 4 | 7 | 0 | 57 |
| 9 | Justin JeffersonMinnesota Vikings·#18 | 17 | 12 | 2 | 40 | 0 | 16.7% | 3.33 | 20.00 | 16 | 129 | 2.7 | 5 | 0 | 0 | 8 | 25 | 9 | 2 | 2 | 0 | 58 |
| 10 | Amon-Ra St. BrownDetroit Lions·#14 | 15 | 18 | 12 | 119 | 1 | 66.7% | 6.61 | 9.92 | 45 | 111 | 1.8 | 5 | 2 | 1 | 4 | 42 | 17 | 2 | 11 | 0 | 62 |
| 11 | Jaylen WaddleMiami Dolphins·#17 | 14 | 9 | 7 | 71 | 3 | 77.8% | 7.89 | 10.14 | 7 | 70 | 2.1 | 4 | 3 | 3 | 7 | 24 | 9 | 1 | 7 | 0 | 34 |
| 12 | Jalen NailorMinnesota Vikings·#1 | 16 | 9 | 4 | 35 | 1 | 44.4% | 3.89 | 8.75 | 4 | 87 | 2.3 | 4 | 1 | 1 | 5 | 20 | 8 | 2 | 4 | 0 | 40 |
| 13 | Keenan AllenLos Angeles Chargers·#13 | 16 | 13 | 8 | 88 | 1 | 61.5% | 6.77 | 11.00 | 26 | 88 | 2.4 | 4 | 2 | 1 | 6 | 24 | 10 | 1 | 8 | 0 | 36 |
| 14 | Khalil ShakirBuffalo Bills·#10 | 16 | 14 | 10 | 78 | 0 | 71.4% | 5.57 | 7.80 | 43 | 44 | 0.7 | 4 | 3 | 0 | 2 | 29 | 6 | 1 | 6 | 2 | 47 |
| 15 | Devaughn VeleNew Orleans Saints·#14 | 10 | 5 | 3 | 25 | 2 | 60.0% | 5.00 | 8.33 | 4 | 15 | 0.6 | 4 | 2 | 2 | 3 | 8 | 4 | 1 | 3 | 0 | 28 |
| 16 | Rashee RiceKansas City Chiefs·#4 | 8 | 14 | 10 | 63 | 3 | 71.4% | 4.50 | 6.30 | 69 | 9 | 0.2 | 4 | 3 | 3 | 2 | 19 | 10 | 1 | 10 | 0 | 37 |
| 17 | Rome OdunzeChicago Bears·#15 | 12 | 13 | 6 | 48 | 2 | 46.1% | 3.69 | 8.00 | 32 | 67 | 2.3 | 4 | 2 | 2 | 4 | 21 | 10 | 0 | 5 | 0 | 47 |
| 18 | Puka NacuaLos Angeles Rams·#12 | 15 | 19 | 17 | 204 | 4 | 89.5% | 10.74 | 12.00 | 89 | 130 | 1.7 | 4 | 4 | 4 | 11 | 45 | 19 | 2 | 17 | 0 | 78 |
| 19 | Romeo DoubsGreen Bay Packers·#87 | 16 | 10 | 8 | 65 | 4 | 80.0% | 6.50 | 8.12 | 11 | 70 | 1.1 | 4 | 3 | 3 | 13 | 34 | 10 | 3 | 8 | 0 | 70 |
| 20 | Ladd McConkeyLos Angeles Chargers·#15 | 16 | 10 | 5 | 42 | 2 | 50.0% | 4.20 | 8.40 | 10 | 55 | 1.3 | 4 | 2 | 2 | 8 | 28 | 7 | 1 | 5 | 0 | 50 |
| 21 | Nico CollinsHouston Texans·#12 | 15 | 10 | 6 | 69 | 1 | 60.0% | 6.90 | 11.50 | 18 | 54 | 1.3 | 4 | 1 | 1 | 6 | 28 | 10 | 1 | 5 | 1 | 45 |
| 22 | Marquise BrownKansas City Chiefs·#5 | 15 | 10 | 8 | 52 | 2 | 80.0% | 5.20 | 6.50 | 14 | 49 | 1.4 | 3 | 3 | 2 | 0 | 25 | 9 | 0 | 6 | 0 | 40 |
| 23 | Jordan AddisonMinnesota Vikings·#3 | 13 | 8 | 4 | 61 | 0 | 50.0% | 7.62 | 15.25 | 10 | 98 | 2.3 | 3 | 1 | 0 | 4 | 21 | 8 | 1 | 4 | 0 | 43 |
| 24 | Chris OlaveNew Orleans Saints·#12 | 14 | 12 | 9 | 83 | 1 | 75.0% | 6.92 | 9.22 | 23 | 97 | 2.3 | 3 | 2 | 1 | 7 | 26 | 9 | 2 | 9 | 0 | 58 |
| 25 | DeMario DouglasNew England Patriots·#3 | 13 | 8 | 6 | 72 | 1 | 75.0% | 9.00 | 12.00 | 28 | 44 | 1.9 | 3 | 2 | 1 | 0 | 18 | 6 | 1 | 5 | 1 | 29 |
| 26 | DJ MooreChicago Bears·#2 | 16 | 8 | 4 | 65 | 1 | 50.0% | 8.12 | 16.25 | 22 | 48 | 1.4 | 3 | 1 | 1 | 6 | 28 | 7 | 1 | 4 | 0 | 61 |
| 27 | Deebo Samuel Sr.Washington Commanders·#1 | 15 | 10 | 7 | 40 | 2 | 70.0% | 4.00 | 5.71 | 8 | 57 | 0.8 | 3 | 2 | 1 | 6 | 25 | 8 | 1 | 5 | 0 | 70 |
| 28 | Xavier LegetteCarolina Panthers·#17 | 15 | 8 | 4 | 43 | 1 | 50.0% | 5.38 | 10.75 | 30 | 40 | 1.3 | 3 | 2 | 1 | 6 | 28 | 5 | 3 | 4 | 0 | 42 |
| 29 | Sterling ShepardTampa Bay Buccaneers·#17 | 13 | 10 | 6 | 58 | 1 | 60.0% | 5.80 | 9.67 | 5 | 67 | 1.8 | 3 | 2 | 1 | 7 | 21 | 7 | 1 | 6 | 0 | 38 |
| 30 | Mike EvansTampa Bay Buccaneers·#13 | 8 | 6 | 2 | 7 | 1 | 33.3% | 1.17 | 3.50 | 0 | 27 | 1.9 | 3 | 1 | 1 | 6 | 17 | 5 | 1 | 2 | 0 | 29 |
| 31 | Xavier WorthyKansas City Chiefs·#1 | 13 | 7 | 3 | 21 | 1 | 42.9% | 3.00 | 7.00 | 15 | 21 | 0.8 | 3 | 1 | 1 | 4 | 28 | 5 | 1 | 3 | 0 | 52 |
| 32 | Stefon DiggsNew England Patriots·#8 | 17 | 12 | 10 | 125 | 3 | 83.3% | 10.42 | 12.50 | 56 | 73 | 1.5 | 3 | 3 | 3 | 4 | 34 | 11 | 3 | 10 | 0 | 53 |
| 33 | Quentin JohnstonLos Angeles Chargers·#1 | 14 | 6 | 3 | 65 | 2 | 50.0% | 10.83 | 21.67 | 18 | 75 | 2.2 | 3 | 1 | 1 | 6 | 21 | 5 | 1 | 2 | 0 | 40 |
| 34 | Darnell MooneyAtlanta Falcons·#1 | 13 | 4 | 3 | 37 | 0 | 75.0% | 9.25 | 12.33 | 1 | 39 | 1.1 | 2 | 1 | 0 | 13 | 24 | 4 | 2 | 3 | 0 | 37 |
| 35 | Andrei IosivasCincinnati Bengals·#80 | 16 | 7 | 4 | 33 | 0 | 57.1% | 4.71 | 8.25 | 12 | 23 | 0.7 | 2 | 0 | 0 | 11 | 36 | 4 | 3 | 4 | 0 | 54 |
| 36 | Chimere DikeTennessee Titans·#17 | 16 | 10 | 9 | 121 | 2 | 90.0% | 12.10 | 13.44 | 47 | 98 | 2.0 | 2 | 2 | 2 | 6 | 23 | 8 | 1 | 9 | 0 | 49 |
| 37 | Christian WatsonGreen Bay Packers·#9 | 9 | 10 | 6 | 93 | 2 | 60.0% | 9.30 | 15.50 | 36 | 96 | 3.2 | 2 | 1 | 1 | 9 | 24 | 10 | 2 | 6 | 1 | 39 |
| 38 | Christian KirkHouston Texans·#13 | 11 | 12 | 7 | 83 | 1 | 58.3% | 6.92 | 11.86 | 63 | 96 | 3.5 | 2 | 1 | 1 | 2 | 20 | 10 | 1 | 7 | 1 | 28 |
| 39 | Isaac TeSlaaDetroit Lions·#18 | 13 | 3 | 1 | 13 | 1 | 33.3% | 4.33 | 13.00 | 0 | 31 | 0.8 | 2 | 1 | 1 | 4 | 20 | 2 | 1 | 1 | 0 | 37 |
| 40 | Drake LondonAtlanta Falcons·#5 | 12 | 12 | 7 | 83 | 2 | 58.3% | 6.92 | 11.86 | 43 | 93 | 2.6 | 2 | 2 | 2 | 10 | 25 | 12 | 2 | 7 | 0 | 37 |
| 41 | Parker WashingtonJacksonville Jaguars·#11 | 15 | 9 | 5 | 102 | 1 | 55.6% | 11.33 | 20.40 | 66 | 85 | 2.2 | 2 | 1 | 1 | 4 | 21 | 8 | 0 | 5 | 0 | 38 |
| 42 | Wan'Dale RobinsonNew York Giants·#17 | 16 | 8 | 3 | 63 | 1 | 37.5% | 7.88 | 21.00 | 9 | 67 | 1.4 | 2 | 0 | 0 | 6 | 26 | 6 | 2 | 3 | 0 | 51 |
| 43 | Van JeffersonTennessee Titans·#11 | 13 | 7 | 3 | 29 | 0 | 42.9% | 4.14 | 9.67 | 2 | 42 | 2.3 | 2 | 1 | 0 | 5 | 15 | 7 | 1 | 3 | 0 | 35 |
| 44 | Kayshon BoutteNew England Patriots·#9 | 13 | 4 | 2 | 14 | 1 | 50.0% | 3.50 | 7.00 | 4 | 30 | 0.7 | 2 | 1 | 1 | 3 | 29 | 4 | 2 | 2 | 1 | 45 |
| 45 | Michael PittmanIndianapolis Colts·#11 | 16 | 12 | 9 | 65 | 2 | 75.0% | 5.42 | 7.22 | 38 | 27 | 0.8 | 2 | 2 | 2 | 3 | 30 | 7 | 0 | 8 | 1 | 54 |
| 46 | Jakobi MeyersJacksonville Jaguars·#3 | 10 | 7 | 4 | 20 | 1 | 57.1% | 2.86 | 5.00 | 1 | 30 | 2.1 | 2 | 1 | 1 | 3 | 14 | 7 | 1 | 4 | 0 | 26 |
| 47 | Jauan JenningsSan Francisco 49ers·#15 | 14 | 7 | 4 | 29 | 1 | 57.1% | 4.14 | 7.25 | 10 | 47 | 1.1 | 2 | 1 | 1 | 9 | 28 | 7 | 2 | 4 | 0 | 41 |
| 48 | Malik WashingtonMiami Dolphins·#6 | 15 | 8 | 5 | 46 | 1 | 62.5% | 5.75 | 9.20 | 21 | 80 | 2.6 | 2 | 2 | 1 | 6 | 22 | 7 | 1 | 5 | 0 | 36 |
| 49 | Terry McLaurinWashington Commanders·#17 | 10 | 12 | 7 | 47 | 1 | 58.3% | 3.92 | 6.71 | 9 | 109 | 2.5 | 2 | 1 | 1 | 5 | 15 | 12 | 0 | 7 | 1 | 43 |
| 50 | Tetairoa McMillanCarolina Panthers·#4 | 17 | 15 | 9 | 142 | 3 | 60.0% | 9.47 | 15.78 | 38 | 167 | 2.6 | 2 | 1 | 1 | 6 | 40 | 14 | 3 | 9 | 0 | 63 |