| 1 | Ja'Marr ChaseCincinnati Bengals·#1 | 15 | 53 | 36 | 480 | 4 | 67.9% | 9.06 | 13.33 | 200 | 426 | 2.3 | 8 | 5 | 3 | 35 | 129 | 41 | 8 | 23 | 2 | 192 |
| 2 | A.J. BrownPhiladelphia Eagles·#11 | 15 | 34 | 21 | 339 | 3 | 61.8% | 9.97 | 16.14 | 106 | 328 | 3.0 | 3 | 1 | 1 | 18 | 77 | 32 | 6 | 14 | 2 | 131 |
| 3 | Deebo Samuel Sr.Washington Commanders·#1 | 15 | 21 | 18 | 203 | 3 | 85.7% | 9.67 | 11.28 | 89 | 160 | 1.1 | 3 | 3 | 2 | 11 | 63 | 13 | 3 | 11 | 2 | 141 |
| 4 | Calvin Austin IIIPittsburgh Steelers·#19 | 13 | 20 | 14 | 168 | 3 | 70.0% | 8.40 | 12.00 | 27 | 220 | 2.3 | 2 | 2 | 2 | 10 | 65 | 18 | 4 | 7 | 1 | 107 |
| 5 | Zay FlowersBaltimore Ravens·#4 | 16 | 32 | 25 | 357 | 3 | 78.1% | 11.16 | 14.28 | 131 | 322 | 2.4 | 4 | 3 | 1 | 14 | 76 | 24 | 5 | 13 | 2 | 136 |
| 6 | Amon-Ra St. BrownDetroit Lions·#14 | 15 | 45 | 29 | 333 | 3 | 64.4% | 7.40 | 11.48 | 129 | 355 | 2.5 | 7 | 5 | 3 | 11 | 94 | 39 | 3 | 15 | 1 | 156 |
| 7 | Marquise BrownKansas City Chiefs·#5 | 15 | 17 | 9 | 180 | 3 | 52.9% | 10.59 | 20.00 | 36 | 246 | 3.2 | 4 | 3 | 3 | 6 | 48 | 13 | 2 | 9 | 0 | 103 |
| 8 | Puka NacuaLos Angeles Rams·#12 | 14 | 40 | 28 | 320 | 3 | 70.0% | 8.00 | 11.43 | 144 | 406 | 3.7 | 4 | 4 | 3 | 14 | 67 | 33 | 3 | 16 | 1 | 111 |
| 9 | Tre TuckerLas Vegas Raiders·#1 | 17 | 20 | 16 | 266 | 3 | 80.0% | 13.30 | 16.62 | 96 | 258 | 1.6 | 4 | 4 | 2 | 15 | 109 | 18 | 5 | 12 | 1 | 166 |
| 10 | Keon ColemanBuffalo Bills·#0 | 12 | 19 | 13 | 172 | 3 | 68.4% | 9.05 | 13.23 | 25 | 238 | 2.9 | 4 | 2 | 2 | 12 | 61 | 15 | 3 | 11 | 0 | 93 |
| 11 | Jauan JenningsSan Francisco 49ers·#15 | 14 | 20 | 12 | 188 | 3 | 60.0% | 9.40 | 15.67 | 62 | 174 | 1.9 | 4 | 2 | 1 | 15 | 71 | 18 | 0 | 8 | 2 | 106 |
| 12 | Jalen NailorMinnesota Vikings·#1 | 17 | 18 | 9 | 91 | 3 | 50.0% | 5.06 | 10.11 | 8 | 162 | 1.2 | 9 | 4 | 3 | 17 | 89 | 15 | 5 | 7 | 2 | 144 |
| 13 | Garrett WilsonNew York Jets·#5 | 6 | 23 | 13 | 136 | 3 | 56.5% | 5.91 | 10.46 | 39 | 179 | 2.0 | 4 | 2 | 2 | 16 | 53 | 21 | 3 | 7 | 0 | 91 |
| 14 | Tetairoa McMillanCarolina Panthers·#4 | 17 | 27 | 16 | 245 | 3 | 59.3% | 9.07 | 15.31 | 77 | 291 | 1.9 | 3 | 3 | 2 | 25 | 104 | 23 | 1 | 12 | 2 | 174 |
| 15 | Isaac TeSlaaDetroit Lions·#18 | 14 | 13 | 6 | 78 | 2 | 46.1% | 6.00 | 13.00 | 28 | 126 | 1.2 | 6 | 3 | 2 | 6 | 62 | 11 | 1 | 5 | 0 | 102 |
| 16 | George PickensDallas Cowboys·#3 | 16 | 37 | 25 | 428 | 2 | 67.6% | 11.57 | 17.12 | 178 | 367 | 2.1 | 9 | 5 | 1 | 23 | 109 | 33 | 3 | 20 | 2 | 171 |
| 17 | Jahdae WalkerChicago Bears·#20 | 4 | 4 | 2 | 31 | 2 | 50.0% | 7.75 | 15.50 | 0 | 56 | 1.9 | 2 | 1 | 1 | 2 | 16 | 3 | 0 | 2 | 0 | 29 |
| 18 | Jordan AddisonMinnesota Vikings·#3 | 14 | 30 | 19 | 278 | 2 | 63.3% | 9.27 | 14.63 | 98 | 307 | 2.2 | 7 | 4 | 2 | 17 | 81 | 27 | 6 | 14 | 2 | 142 |
| 19 | Greg DortchArizona Cardinals·#4 | 12 | 13 | 11 | 133 | 2 | 84.6% | 10.23 | 12.09 | 96 | 78 | 1.0 | 2 | 2 | 1 | 13 | 46 | 7 | 3 | 5 | 0 | 79 |
| 20 | Rome OdunzeChicago Bears·#15 | 12 | 22 | 11 | 148 | 2 | 50.0% | 6.73 | 13.45 | 33 | 279 | 2.8 | 4 | 3 | 2 | 11 | 50 | 16 | 3 | 9 | 1 | 104 |
| 21 | Michael WilsonArizona Cardinals·#14 | 17 | 44 | 21 | 247 | 2 | 47.7% | 5.61 | 11.76 | 73 | 476 | 2.6 | 8 | 3 | 2 | 39 | 115 | 40 | 8 | 14 | 1 | 203 |
| 22 | Marvin Harrison Jr.Arizona Cardinals·#18 | 10 | 16 | 9 | 124 | 2 | 56.3% | 7.75 | 13.78 | 24 | 199 | 2.8 | 3 | 2 | 2 | 13 | 40 | 16 | 3 | 6 | 0 | 80 |
| 23 | Roman WilsonPittsburgh Steelers·#10 | 12 | 9 | 6 | 67 | 2 | 66.7% | 7.44 | 11.17 | 31 | 85 | 1.2 | 0 | 0 | 0 | 4 | 40 | 5 | 3 | 3 | 1 | 65 |
| 24 | Wan'Dale RobinsonNew York Giants·#17 | 16 | 38 | 16 | 210 | 2 | 42.1% | 5.53 | 13.12 | 48 | 416 | 2.8 | 8 | 2 | 1 | 26 | 86 | 28 | 2 | 8 | 1 | 161 |
| 25 | Tee HigginsCincinnati Bengals·#5 | 15 | 31 | 16 | 242 | 2 | 51.6% | 7.81 | 15.12 | 41 | 349 | 2.5 | 3 | 1 | 1 | 28 | 112 | 30 | 6 | 12 | 2 | 173 |
| 26 | Troy FranklinDenver Broncos·#11 | 17 | 26 | 14 | 201 | 2 | 53.9% | 7.73 | 14.36 | 77 | 265 | 2.3 | 9 | 5 | 2 | 17 | 85 | 20 | 6 | 8 | 0 | 140 |
| 27 | Tim PatrickJacksonville Jaguars·#17 | 13 | 6 | 4 | 60 | 2 | 66.7% | 10.00 | 15.00 | 16 | 215 | 1.5 | 3 | 2 | 1 | 8 | 27 | 4 | 1 | 3 | 1 | 55 |
| 28 | Rashee RiceKansas City Chiefs·#4 | 7 | 19 | 12 | 187 | 2 | 63.2% | 9.84 | 15.58 | 128 | 99 | 1.2 | 5 | 2 | 2 | 4 | 42 | 14 | 3 | 9 | 0 | 80 |
| 29 | Nico CollinsHouston Texans·#12 | 15 | 31 | 16 | 246 | 2 | 51.6% | 7.94 | 15.38 | 59 | 310 | 3.2 | 9 | 3 | 1 | 12 | 68 | 29 | 5 | 9 | 2 | 115 |
| 30 | Ryan FlournoyDallas Cowboys·#19 | 14 | 18 | 13 | 169 | 2 | 72.2% | 9.39 | 13.00 | 39 | 198 | 2.0 | 1 | 1 | 1 | 17 | 63 | 17 | 1 | 11 | 0 | 102 |
| 31 | DeVonta SmithPhiladelphia Eagles·#6 | 15 | 28 | 21 | 223 | 2 | 75.0% | 7.96 | 10.62 | 52 | 220 | 1.8 | 2 | 1 | 1 | 19 | 78 | 24 | 7 | 10 | 2 | 142 |
| 32 | Davante AdamsLos Angeles Rams·#17 | 13 | 23 | 11 | 173 | 2 | 47.8% | 7.52 | 15.73 | 37 | 315 | 4.3 | 4 | 2 | 2 | 12 | 51 | 22 | 2 | 9 | 2 | 78 |
| 33 | Devaughn VeleNew Orleans Saints·#14 | 9 | 17 | 9 | 93 | 2 | 52.9% | 5.47 | 10.33 | 7 | 150 | 1.8 | 4 | 2 | 2 | 8 | 42 | 12 | 3 | 7 | 0 | 83 |
| 34 | Chris OlaveNew Orleans Saints·#12 | 16 | 49 | 33 | 407 | 2 | 67.3% | 8.31 | 12.33 | 95 | 418 | 2.8 | 3 | 2 | 1 | 24 | 128 | 44 | 6 | 20 | 2 | 207 |
| 35 | Josh DownsIndianapolis Colts·#2 | 13 | 17 | 11 | 84 | 2 | 64.7% | 4.94 | 7.64 | 13 | 77 | 1.2 | 5 | 4 | 2 | 15 | 59 | 15 | 1 | 7 | 2 | 110 |
| 36 | Jayden HigginsHouston Texans·#81 | 17 | 21 | 14 | 169 | 2 | 66.7% | 8.05 | 12.07 | 41 | 189 | 1.9 | 4 | 2 | 1 | 12 | 58 | 20 | 2 | 10 | 0 | 97 |
| 37 | Chimere DikeTennessee Titans·#17 | 16 | 27 | 16 | 92 | 2 | 59.3% | 3.41 | 5.75 | 57 | 145 | 0.9 | 11 | 7 | 2 | 18 | 104 | 13 | 4 | 5 | 2 | 178 |
| 38 | DeAndre HopkinsBaltimore Ravens·#10 | 15 | 13 | 8 | 97 | 1 | 61.5% | 7.46 | 12.12 | 6 | 174 | 3.3 | 1 | 0 | 0 | 9 | 34 | 12 | 2 | 6 | 2 | 58 |
| 39 | Christian WatsonGreen Bay Packers·#9 | 10 | 11 | 7 | 102 | 1 | 63.6% | 9.27 | 14.57 | 13 | 159 | 2.6 | 1 | 1 | 1 | 10 | 35 | 11 | 2 | 5 | 1 | 62 |
| 40 | Cooper KuppSeattle Seahawks·#10 | 14 | 24 | 14 | 131 | 1 | 58.3% | 5.46 | 9.36 | 60 | 143 | 1.5 | 7 | 3 | 1 | 6 | 69 | 19 | 3 | 6 | 3 | 114 |
| 41 | DK MetcalfPittsburgh Steelers·#4 | 15 | 21 | 16 | 145 | 1 | 76.2% | 6.90 | 9.06 | 47 | 141 | 1.1 | 2 | 1 | 0 | 13 | 86 | 18 | 5 | 9 | 2 | 147 |
| 42 | Chris Godwin Jr.Tampa Bay Buccaneers·#14 | 9 | 17 | 12 | 151 | 1 | 70.6% | 8.88 | 12.58 | 85 | 111 | 1.4 | 3 | 1 | 1 | 13 | 47 | 13 | 0 | 9 | 0 | 85 |
| 43 | Andrei IosivasCincinnati Bengals·#80 | 17 | 21 | 8 | 110 | 1 | 38.1% | 5.24 | 13.75 | 30 | 146 | 1.3 | 3 | 1 | 1 | 31 | 121 | 18 | 7 | 7 | 2 | 183 |
| 44 | Allen LazardNew York Jets·#10 | 10 | 10 | 6 | 41 | 1 | 60.0% | 4.10 | 6.83 | 11 | 89 | 1.1 | 5 | 3 | 1 | 18 | 46 | 7 | 4 | 4 | 0 | 81 |
| 45 | Darnell MooneyAtlanta Falcons·#1 | 14 | 24 | 10 | 144 | 1 | 41.7% | 6.00 | 14.40 | 28 | 225 | 3.0 | 3 | 1 | 0 | 22 | 76 | 21 | 4 | 7 | 0 | 127 |
| 46 | David SillsAtlanta Falcons·#87 | 16 | 14 | 6 | 80 | 1 | 42.9% | 5.71 | 13.33 | 24 | 151 | 1.4 | 2 | 1 | 1 | 18 | 69 | 11 | 3 | 5 | 0 | 119 |
| 47 | Romeo DoubsGreen Bay Packers·#87 | 16 | 13 | 8 | 95 | 1 | 61.5% | 7.31 | 11.88 | 16 | 107 | 1.2 | 4 | 2 | 1 | 14 | 58 | 11 | 3 | 5 | 0 | 112 |
| 48 | Michael PittmanIndianapolis Colts·#11 | 15 | 25 | 17 | 151 | 1 | 68.0% | 6.04 | 8.88 | 52 | 207 | 1.9 | 3 | 2 | 1 | 17 | 75 | 22 | 1 | 9 | 2 | 128 |
| 49 | Mike EvansTampa Bay Buccaneers·#13 | 7 | 14 | 8 | 64 | 1 | 57.1% | 4.57 | 8.00 | 8 | 139 | 2.6 | 2 | 2 | 1 | 7 | 42 | 13 | 0 | 5 | 0 | 66 |
| 50 | Mitchell TinsleyCincinnati Bengals·#82 | 14 | 8 | 3 | 45 | 1 | 37.5% | 5.62 | 15.00 | 0 | 52 | 2.8 | 2 | 1 | 1 | 5 | 26 | 7 | 2 | 3 | 0 | 48 |