| 1 | Troy FranklinDenver Broncos·#11 | 17 | 45 | 29 | 357 | 3 | 64.4% | 7.93 | 12.31 | 139 | 440 | 2.1 | 14 | 9 | 2 | 23 | 149 | 34 | 7 | 15 | 0 | 238 |
| 2 | Chimere DikeTennessee Titans·#17 | 16 | 35 | 22 | 135 | 3 | 62.9% | 3.86 | 6.14 | 78 | 219 | 0.9 | 13 | 9 | 3 | 22 | 137 | 17 | 6 | 7 | 3 | 247 |
| 3 | Amon-Ra St. BrownDetroit Lions·#14 | 16 | 71 | 45 | 532 | 4 | 63.4% | 7.49 | 11.82 | 177 | 622 | 2.5 | 12 | 7 | 4 | 19 | 169 | 63 | 3 | 27 | 1 | 266 |
| 4 | George PickensDallas Cowboys·#3 | 16 | 62 | 41 | 692 | 4 | 66.1% | 11.16 | 16.88 | 276 | 637 | 2.1 | 11 | 7 | 1 | 42 | 195 | 57 | 9 | 32 | 2 | 298 |
| 5 | Nico CollinsHouston Texans·#12 | 15 | 52 | 28 | 434 | 3 | 53.9% | 8.35 | 15.50 | 112 | 544 | 2.9 | 11 | 4 | 2 | 24 | 127 | 49 | 6 | 18 | 2 | 208 |
| 6 | Emeka EgbukaTampa Bay Buccaneers·#2 | 17 | 68 | 30 | 561 | 3 | 44.1% | 8.25 | 18.70 | 156 | 876 | 3.6 | 11 | 3 | 1 | 32 | 170 | 61 | 4 | 18 | 2 | 285 |
| 7 | Courtland SuttonDenver Broncos·#14 | 17 | 60 | 35 | 475 | 1 | 58.3% | 7.92 | 13.57 | 92 | 595 | 2.5 | 10 | 2 | 1 | 29 | 192 | 51 | 9 | 25 | 0 | 310 |
| 8 | Jauan JenningsSan Francisco 49ers·#15 | 15 | 42 | 24 | 329 | 5 | 57.1% | 7.83 | 13.71 | 89 | 405 | 2.1 | 10 | 4 | 3 | 32 | 157 | 37 | 5 | 17 | 3 | 216 |
| 9 | Keenan AllenLos Angeles Chargers·#13 | 17 | 60 | 40 | 378 | 3 | 66.7% | 6.30 | 9.45 | 125 | 464 | 2.1 | 10 | 4 | 3 | 24 | 141 | 49 | 2 | 28 | 0 | 225 |
| 10 | Keon ColemanBuffalo Bills·#0 | 13 | 37 | 25 | 300 | 4 | 67.6% | 8.11 | 12.00 | 74 | 351 | 2.1 | 10 | 5 | 3 | 23 | 126 | 31 | 3 | 19 | 0 | 179 |
| 11 | Wan'Dale RobinsonNew York Giants·#17 | 16 | 71 | 41 | 427 | 2 | 57.8% | 6.01 | 10.41 | 177 | 531 | 2.0 | 10 | 2 | 1 | 41 | 161 | 53 | 6 | 15 | 2 | 294 |
| 12 | Michael WilsonArizona Cardinals·#14 | 17 | 68 | 39 | 530 | 3 | 57.4% | 7.79 | 13.59 | 154 | 713 | 2.5 | 10 | 4 | 2 | 56 | 207 | 64 | 12 | 25 | 2 | 344 |
| 13 | Drake LondonAtlanta Falcons·#5 | 12 | 47 | 23 | 318 | 1 | 48.9% | 6.77 | 13.83 | 57 | 397 | 2.7 | 9 | 2 | 1 | 29 | 107 | 44 | 5 | 17 | 0 | 183 |
| 14 | Cooper KuppSeattle Seahawks·#10 | 16 | 40 | 24 | 277 | 2 | 60.0% | 6.92 | 11.54 | 121 | 293 | 1.5 | 9 | 4 | 2 | 13 | 138 | 34 | 7 | 13 | 5 | 212 |
| 15 | Chris OlaveNew Orleans Saints·#12 | 16 | 77 | 50 | 606 | 7 | 64.9% | 7.87 | 12.12 | 121 | 675 | 2.9 | 9 | 6 | 5 | 36 | 199 | 69 | 11 | 31 | 4 | 326 |
| 16 | CeeDee LambDallas Cowboys·#88 | 12 | 53 | 31 | 461 | 0 | 58.5% | 8.70 | 14.87 | 95 | 606 | 3.5 | 9 | 3 | 0 | 25 | 136 | 49 | 8 | 17 | 1 | 202 |
| 17 | Ja'Marr ChaseCincinnati Bengals·#1 | 16 | 82 | 59 | 734 | 4 | 72.0% | 8.95 | 12.44 | 320 | 639 | 2.1 | 9 | 6 | 3 | 57 | 218 | 60 | 12 | 36 | 2 | 326 |
| 18 | Jalen NailorMinnesota Vikings·#1 | 17 | 26 | 13 | 154 | 3 | 50.0% | 5.92 | 11.85 | 15 | 272 | 1.3 | 9 | 4 | 3 | 28 | 127 | 21 | 7 | 11 | 3 | 221 |
| 19 | Justin JeffersonMinnesota Vikings·#18 | 17 | 59 | 29 | 345 | 1 | 49.1% | 5.85 | 11.90 | 110 | 651 | 2.8 | 9 | 3 | 1 | 33 | 151 | 50 | 10 | 15 | 5 | 277 |
| 20 | Josh DownsIndianapolis Colts·#2 | 16 | 32 | 21 | 203 | 3 | 65.6% | 6.34 | 9.67 | 42 | 192 | 1.4 | 9 | 7 | 3 | 30 | 103 | 29 | 4 | 14 | 4 | 181 |
| 21 | Michael PittmanIndianapolis Colts·#11 | 17 | 53 | 37 | 392 | 2 | 69.8% | 7.40 | 10.59 | 129 | 413 | 1.8 | 9 | 4 | 2 | 36 | 159 | 47 | 6 | 20 | 4 | 249 |
| 22 | Khalil ShakirBuffalo Bills·#10 | 16 | 53 | 41 | 487 | 2 | 77.4% | 9.19 | 11.88 | 290 | 210 | 0.9 | 9 | 5 | 1 | 31 | 153 | 38 | 6 | 18 | 1 | 250 |
| 23 | Jordan AddisonMinnesota Vikings·#3 | 14 | 42 | 25 | 347 | 3 | 59.5% | 8.26 | 13.88 | 105 | 493 | 2.1 | 9 | 6 | 3 | 28 | 128 | 39 | 8 | 19 | 3 | 237 |
| 24 | Jameson WilliamsDetroit Lions·#1 | 17 | 57 | 36 | 638 | 3 | 63.2% | 11.19 | 17.72 | 285 | 646 | 2.2 | 8 | 3 | 1 | 19 | 192 | 48 | 3 | 26 | 1 | 298 |
| 25 | Isaac TeSlaaDetroit Lions·#18 | 17 | 17 | 9 | 118 | 4 | 52.9% | 6.94 | 13.11 | 28 | 180 | 1.2 | 8 | 5 | 4 | 11 | 95 | 15 | 1 | 8 | 0 | 153 |
| 26 | Deebo Samuel Sr.Washington Commanders·#1 | 16 | 44 | 32 | 335 | 5 | 72.7% | 7.61 | 10.47 | 171 | 295 | 1.1 | 8 | 7 | 4 | 32 | 119 | 27 | 5 | 18 | 3 | 272 |
| 27 | Davante AdamsLos Angeles Rams·#17 | 14 | 46 | 23 | 345 | 4 | 50.0% | 7.50 | 15.00 | 72 | 638 | 3.7 | 8 | 4 | 4 | 32 | 127 | 44 | 9 | 20 | 3 | 185 |
| 28 | Puka NacuaLos Angeles Rams·#12 | 16 | 77 | 59 | 744 | 5 | 76.6% | 9.66 | 12.61 | 317 | 679 | 3.1 | 8 | 8 | 4 | 28 | 147 | 63 | 11 | 35 | 2 | 225 |
| 29 | Rashee RiceKansas City Chiefs·#4 | 8 | 38 | 23 | 323 | 2 | 60.5% | 8.50 | 14.04 | 221 | 222 | 1.6 | 8 | 5 | 2 | 11 | 80 | 25 | 4 | 14 | 0 | 140 |
| 30 | Marvin Harrison Jr.Arizona Cardinals·#18 | 11 | 35 | 18 | 255 | 2 | 51.4% | 7.29 | 14.17 | 59 | 452 | 2.8 | 7 | 3 | 2 | 20 | 98 | 33 | 5 | 12 | 1 | 171 |
| 31 | Jaxon Smith-NjigbaSeattle Seahawks·#11 | 17 | 74 | 54 | 859 | 3 | 73.0% | 11.61 | 15.91 | 298 | 822 | 3.5 | 7 | 4 | 2 | 13 | 155 | 63 | 6 | 42 | 5 | 239 |
| 32 | Dyami BrownJacksonville Jaguars·#5 | 13 | 18 | 10 | 125 | 0 | 55.6% | 6.94 | 12.50 | 9 | 196 | 2.5 | 7 | 3 | 0 | 10 | 54 | 15 | 3 | 7 | 2 | 99 |
| 33 | Sterling ShepardTampa Bay Buccaneers·#17 | 13 | 31 | 19 | 174 | 1 | 61.3% | 5.61 | 9.16 | 75 | 292 | 1.5 | 7 | 3 | 1 | 23 | 113 | 20 | 2 | 9 | 2 | 195 |
| 34 | Zay FlowersBaltimore Ravens·#4 | 17 | 60 | 45 | 697 | 4 | 75.0% | 11.62 | 15.49 | 291 | 604 | 2.4 | 7 | 4 | 1 | 29 | 143 | 45 | 11 | 26 | 4 | 250 |
| 35 | Parker WashingtonJacksonville Jaguars·#11 | 15 | 48 | 25 | 375 | 1 | 52.1% | 7.81 | 15.00 | 173 | 510 | 2.5 | 7 | 3 | 1 | 20 | 118 | 44 | 3 | 17 | 1 | 213 |
| 36 | Marquise BrownKansas City Chiefs·#5 | 16 | 37 | 24 | 339 | 4 | 64.9% | 9.16 | 14.12 | 88 | 377 | 2.4 | 7 | 5 | 4 | 13 | 114 | 27 | 4 | 18 | 0 | 201 |
| 37 | Romeo DoubsGreen Bay Packers·#87 | 16 | 26 | 19 | 234 | 2 | 73.1% | 9.00 | 12.32 | 49 | 273 | 1.4 | 6 | 4 | 1 | 26 | 121 | 22 | 4 | 12 | 1 | 217 |
| 38 | Rashod BatemanBaltimore Ravens·#7 | 13 | 19 | 8 | 149 | 1 | 42.1% | 7.84 | 18.62 | 20 | 254 | 1.6 | 6 | 2 | 1 | 16 | 99 | 16 | 7 | 8 | 2 | 158 |
| 39 | Olamide ZaccheausChicago Bears·#14 | 16 | 27 | 14 | 102 | 1 | 51.9% | 3.78 | 7.29 | 38 | 156 | 0.9 | 6 | 3 | 1 | 20 | 95 | 20 | 4 | 4 | 1 | 183 |
| 40 | Rome OdunzeChicago Bears·#15 | 12 | 38 | 18 | 281 | 3 | 47.4% | 7.39 | 15.61 | 89 | 456 | 2.4 | 6 | 3 | 2 | 18 | 107 | 30 | 6 | 16 | 1 | 206 |
| 41 | Xavier LegetteCarolina Panthers·#17 | 15 | 39 | 23 | 272 | 1 | 59.0% | 6.97 | 11.83 | 26 | 331 | 1.9 | 6 | 2 | 0 | 29 | 127 | 34 | 2 | 12 | 3 | 210 |
| 42 | Tee HigginsCincinnati Bengals·#5 | 15 | 50 | 28 | 394 | 4 | 56.0% | 7.88 | 14.07 | 73 | 504 | 2.2 | 6 | 3 | 2 | 42 | 176 | 47 | 7 | 20 | 2 | 270 |
| 43 | Ladd McConkeyLos Angeles Chargers·#15 | 16 | 44 | 27 | 363 | 2 | 61.4% | 8.25 | 13.44 | 162 | 345 | 1.7 | 6 | 3 | 2 | 28 | 153 | 33 | 1 | 15 | 0 | 263 |
| 44 | JuJu Smith-SchusterKansas City Chiefs·#9 | 17 | 22 | 17 | 146 | 0 | 77.3% | 6.64 | 8.59 | 72 | 98 | 0.6 | 6 | 2 | 0 | 14 | 106 | 15 | 1 | 8 | 0 | 190 |
| 45 | Darius SlaytonNew York Giants·#18 | 14 | 30 | 16 | 210 | 0 | 53.3% | 7.00 | 13.12 | 72 | 295 | 1.6 | 6 | 1 | 0 | 21 | 121 | 23 | 3 | 9 | 2 | 211 |
| 46 | Tre TuckerLas Vegas Raiders·#1 | 17 | 38 | 27 | 357 | 3 | 71.0% | 9.39 | 13.22 | 167 | 395 | 1.4 | 6 | 5 | 2 | 25 | 184 | 29 | 10 | 15 | 1 | 293 |
| 47 | Allen LazardNew York Jets·#10 | 10 | 13 | 8 | 55 | 1 | 61.5% | 4.23 | 6.88 | 23 | 124 | 1.2 | 5 | 3 | 1 | 21 | 59 | 8 | 4 | 4 | 0 | 106 |
| 48 | A.J. BrownPhiladelphia Eagles·#11 | 15 | 56 | 31 | 503 | 5 | 55.4% | 8.98 | 16.23 | 137 | 623 | 3.1 | 5 | 3 | 2 | 31 | 137 | 52 | 9 | 20 | 3 | 249 |
| 49 | Brian Thomas Jr.Jacksonville Jaguars·#7 | 14 | 41 | 16 | 299 | 0 | 39.0% | 7.29 | 18.69 | 84 | 576 | 3.1 | 5 | 1 | 0 | 23 | 132 | 39 | 5 | 12 | 0 | 210 |
| 50 | Elic AyomanorTennessee Titans·#5 | 16 | 45 | 22 | 244 | 1 | 48.9% | 5.42 | 11.09 | 55 | 400 | 1.8 | 5 | 2 | 1 | 31 | 160 | 40 | 6 | 15 | 5 | 284 |