| 1 | Ja'Marr ChaseCincinnati Bengals·#1 | 16 | 183 | 125 | 1,412 | 8 | 68.3% | 7.72 | 11.30 | 640 | 1,423 | 2.3 | 22 | 13 | 7 | 111 | 433 | 140 | 22 | 73 | 6 | 673 |
| 2 | Michael WilsonArizona Cardinals·#14 | 17 | 125 | 78 | 1,006 | 7 | 62.4% | 8.05 | 12.90 | 273 | 1,231 | 2.3 | 17 | 8 | 4 | 97 | 385 | 117 | 20 | 51 | 6 | 645 |
| 3 | Andrei IosivasCincinnati Bengals·#80 | 17 | 58 | 33 | 435 | 2 | 56.9% | 7.50 | 13.18 | 103 | 506 | 1.1 | 7 | 2 | 1 | 94 | 371 | 44 | 19 | 24 | 3 | 571 |
| 4 | George PickensDallas Cowboys·#3 | 17 | 137 | 93 | 1,431 | 9 | 67.9% | 10.45 | 15.39 | 479 | 1,388 | 2.5 | 24 | 11 | 4 | 81 | 421 | 127 | 17 | 73 | 5 | 629 |
| 5 | Tee HigginsCincinnati Bengals·#5 | 15 | 99 | 59 | 865 | 11 | 59.6% | 8.74 | 14.66 | 166 | 1,088 | 2.4 | 16 | 10 | 4 | 78 | 355 | 92 | 16 | 41 | 5 | 544 |
| 6 | Justin JeffersonMinnesota Vikings·#18 | 17 | 140 | 84 | 1,048 | 2 | 60.0% | 7.49 | 12.48 | 451 | 1,245 | 2.3 | 19 | 5 | 2 | 75 | 323 | 110 | 21 | 50 | 7 | 592 |
| 7 | Michael PittmanIndianapolis Colts·#11 | 17 | 113 | 80 | 795 | 7 | 70.8% | 7.04 | 9.94 | 268 | 822 | 1.6 | 18 | 8 | 5 | 74 | 361 | 97 | 21 | 47 | 6 | 556 |
| 8 | Jerry JeudyCleveland Browns·#3 | 17 | 104 | 50 | 602 | 2 | 48.1% | 5.79 | 12.04 | 166 | 1,156 | 2.1 | 9 | 1 | 0 | 73 | 331 | 94 | 11 | 32 | 4 | 591 |
| 9 | Jauan JenningsSan Francisco 49ers·#15 | 15 | 92 | 55 | 645 | 9 | 59.8% | 7.01 | 11.73 | 181 | 757 | 1.9 | 22 | 11 | 7 | 72 | 319 | 85 | 11 | 36 | 5 | 464 |
| 10 | Chris OlaveNew Orleans Saints·#12 | 16 | 155 | 100 | 1,164 | 9 | 64.5% | 7.51 | 11.64 | 289 | 1,298 | 2.9 | 15 | 7 | 5 | 70 | 378 | 134 | 18 | 53 | 9 | 626 |
| 11 | Darnell MooneyAtlanta Falcons·#1 | 15 | 72 | 32 | 443 | 1 | 44.4% | 6.15 | 13.84 | 73 | 751 | 2.1 | 8 | 3 | 0 | 69 | 282 | 66 | 12 | 25 | 4 | 475 |
| 12 | Wan'Dale RobinsonNew York Giants·#17 | 16 | 140 | 92 | 1,014 | 4 | 65.7% | 7.24 | 11.02 | 386 | 1,061 | 2.1 | 14 | 4 | 1 | 69 | 321 | 104 | 12 | 39 | 3 | 550 |
| 13 | Alec PierceIndianapolis Colts·#14 | 15 | 81 | 47 | 1,003 | 6 | 58.0% | 12.38 | 21.34 | 174 | 1,383 | 3.1 | 9 | 4 | 4 | 69 | 299 | 78 | 19 | 41 | 4 | 488 |
| 14 | Brian Thomas Jr.Jacksonville Jaguars·#7 | 14 | 90 | 48 | 707 | 2 | 53.3% | 7.86 | 14.73 | 159 | 1,178 | 2.7 | 7 | 2 | 1 | 65 | 309 | 81 | 11 | 33 | 1 | 482 |
| 15 | Davante AdamsLos Angeles Rams·#17 | 14 | 113 | 60 | 789 | 14 | 53.1% | 6.98 | 13.15 | 117 | 1,346 | 3.5 | 32 | 13 | 12 | 64 | 285 | 106 | 17 | 51 | 4 | 413 |
| 16 | Courtland SuttonDenver Broncos·#14 | 17 | 123 | 74 | 1,019 | 7 | 60.2% | 8.28 | 13.77 | 222 | 1,149 | 2.4 | 20 | 7 | 4 | 64 | 398 | 109 | 11 | 52 | 2 | 627 |
| 17 | Tre TuckerLas Vegas Raiders·#1 | 17 | 92 | 57 | 696 | 5 | 62.0% | 7.57 | 12.21 | 291 | 869 | 1.5 | 10 | 6 | 3 | 63 | 361 | 70 | 15 | 32 | 1 | 611 |
| 18 | Jordan AddisonMinnesota Vikings·#3 | 14 | 78 | 42 | 610 | 3 | 53.9% | 7.82 | 14.52 | 139 | 1,017 | 2.2 | 13 | 7 | 3 | 62 | 263 | 72 | 18 | 26 | 4 | 465 |
| 19 | Puka NacuaLos Angeles Rams·#12 | 16 | 166 | 129 | 1,715 | 10 | 77.7% | 10.33 | 13.29 | 666 | 1,544 | 3.2 | 17 | 14 | 5 | 61 | 327 | 138 | 19 | 80 | 3 | 493 |
| 20 | DJ MooreChicago Bears·#2 | 17 | 85 | 50 | 686 | 6 | 58.8% | 8.07 | 13.72 | 207 | 805 | 1.6 | 11 | 6 | 3 | 61 | 324 | 55 | 18 | 32 | 2 | 614 |
| 21 | Deebo Samuel Sr.Washington Commanders·#1 | 16 | 98 | 72 | 727 | 5 | 73.5% | 7.42 | 10.10 | 466 | 533 | 1.0 | 12 | 9 | 4 | 59 | 251 | 56 | 9 | 33 | 4 | 548 |
| 22 | Josh DownsIndianapolis Colts·#2 | 16 | 87 | 58 | 566 | 4 | 66.7% | 6.51 | 9.76 | 137 | 524 | 1.6 | 15 | 10 | 4 | 59 | 249 | 82 | 13 | 36 | 6 | 407 |
| 23 | Tetairoa McMillanCarolina Panthers·#4 | 17 | 119 | 70 | 1,013 | 7 | 58.8% | 8.51 | 14.47 | 268 | 1,242 | 2.5 | 15 | 10 | 4 | 58 | 341 | 106 | 10 | 55 | 6 | 559 |
| 24 | Romeo DoubsGreen Bay Packers·#87 | 16 | 86 | 55 | 726 | 6 | 64.0% | 8.44 | 13.20 | 163 | 914 | 2.3 | 18 | 10 | 5 | 58 | 271 | 74 | 11 | 41 | 4 | 475 |
| 25 | Drake LondonAtlanta Falcons·#5 | 12 | 112 | 68 | 921 | 7 | 60.7% | 8.22 | 13.54 | 229 | 1,068 | 3.0 | 16 | 9 | 7 | 58 | 241 | 107 | 12 | 47 | 3 | 407 |
| 26 | Ladd McConkeyLos Angeles Chargers·#15 | 16 | 105 | 66 | 789 | 6 | 62.9% | 7.51 | 11.95 | 310 | 800 | 1.8 | 15 | 7 | 4 | 56 | 327 | 83 | 5 | 35 | 3 | 562 |
| 27 | Emeka EgbukaTampa Bay Buccaneers·#2 | 17 | 128 | 63 | 940 | 6 | 49.2% | 7.34 | 14.92 | 335 | 1,274 | 2.9 | 15 | 5 | 2 | 54 | 328 | 107 | 8 | 34 | 4 | 549 |
| 28 | Keenan AllenLos Angeles Chargers·#13 | 17 | 121 | 81 | 777 | 4 | 66.9% | 6.42 | 9.59 | 231 | 929 | 2.2 | 15 | 7 | 4 | 54 | 276 | 100 | 5 | 49 | 2 | 464 |
| 29 | CeeDee LambDallas Cowboys·#88 | 14 | 116 | 75 | 1,077 | 3 | 64.7% | 9.28 | 14.36 | 323 | 1,262 | 3.0 | 17 | 8 | 2 | 54 | 307 | 103 | 11 | 44 | 4 | 466 |
| 30 | Zay FlowersBaltimore Ravens·#4 | 17 | 117 | 86 | 1,211 | 5 | 73.5% | 10.35 | 14.08 | 458 | 1,156 | 2.3 | 12 | 7 | 1 | 53 | 297 | 87 | 17 | 49 | 8 | 519 |
| 31 | DeVonta SmithPhiladelphia Eagles·#6 | 17 | 114 | 77 | 1,008 | 4 | 67.5% | 8.84 | 13.09 | 293 | 1,167 | 2.3 | 12 | 7 | 2 | 53 | 316 | 95 | 17 | 45 | 5 | 591 |
| 32 | Nico CollinsHouston Texans·#12 | 15 | 121 | 71 | 1,119 | 6 | 58.7% | 9.25 | 15.76 | 324 | 1,401 | 3.2 | 19 | 8 | 3 | 52 | 289 | 110 | 10 | 48 | 2 | 480 |
| 33 | Jalen NailorMinnesota Vikings·#1 | 17 | 50 | 29 | 446 | 4 | 58.0% | 8.92 | 15.38 | 112 | 562 | 1.3 | 13 | 6 | 4 | 52 | 242 | 40 | 14 | 23 | 5 | 439 |
| 34 | Marvin Harrison Jr.Arizona Cardinals·#18 | 12 | 74 | 41 | 610 | 4 | 55.4% | 8.24 | 14.88 | 119 | 923 | 2.4 | 11 | 6 | 4 | 51 | 229 | 69 | 10 | 30 | 4 | 388 |
| 35 | Elic AyomanorTennessee Titans·#5 | 16 | 88 | 41 | 515 | 4 | 46.6% | 5.85 | 12.56 | 115 | 986 | 2.1 | 8 | 5 | 4 | 51 | 282 | 81 | 10 | 30 | 6 | 520 |
| 36 | David SillsAtlanta Falcons·#87 | 17 | 36 | 18 | 191 | 2 | 50.0% | 5.31 | 10.61 | 56 | 335 | 1.1 | 6 | 3 | 2 | 50 | 208 | 30 | 7 | 9 | 3 | 355 |
| 37 | Khalil ShakirBuffalo Bills·#10 | 16 | 95 | 72 | 719 | 4 | 75.8% | 7.57 | 9.99 | 508 | 289 | 0.8 | 14 | 10 | 2 | 50 | 266 | 55 | 7 | 28 | 3 | 427 |
| 38 | A.J. BrownPhiladelphia Eagles·#11 | 15 | 121 | 78 | 1,003 | 7 | 64.5% | 8.29 | 12.86 | 268 | 1,178 | 2.7 | 13 | 9 | 3 | 50 | 301 | 108 | 14 | 47 | 5 | 536 |
| 39 | Troy FranklinDenver Broncos·#11 | 17 | 106 | 65 | 715 | 6 | 61.3% | 6.75 | 11.00 | 282 | 940 | 2.6 | 21 | 14 | 4 | 50 | 319 | 73 | 9 | 33 | 2 | 500 |
| 40 | Kendrick BourneSan Francisco 49ers·#84 | 16 | 53 | 37 | 551 | 0 | 69.8% | 10.40 | 14.89 | 165 | 538 | 1.6 | 2 | 1 | 0 | 50 | 254 | 43 | 9 | 27 | 4 | 363 |
| 41 | Xavier LegetteCarolina Panthers·#17 | 15 | 64 | 35 | 363 | 3 | 54.7% | 5.67 | 10.37 | 75 | 514 | 1.6 | 12 | 5 | 2 | 49 | 246 | 52 | 7 | 18 | 6 | 404 |
| 42 | DK MetcalfPittsburgh Steelers·#4 | 15 | 96 | 59 | 850 | 6 | 61.5% | 8.85 | 14.41 | 414 | 877 | 1.7 | 13 | 8 | 3 | 48 | 303 | 81 | 15 | 37 | 5 | 552 |
| 43 | Parker WashingtonJacksonville Jaguars·#11 | 16 | 96 | 58 | 847 | 5 | 60.4% | 8.82 | 14.60 | 265 | 1,084 | 2.7 | 16 | 10 | 4 | 47 | 252 | 83 | 8 | 38 | 3 | 431 |
| 44 | Ricky PearsallSan Francisco 49ers·#1 | 9 | 52 | 36 | 528 | 0 | 69.2% | 10.15 | 14.67 | 74 | 640 | 2.5 | 4 | 1 | 0 | 46 | 197 | 46 | 8 | 28 | 3 | 287 |
| 45 | Stefon DiggsNew England Patriots·#8 | 17 | 100 | 85 | 1,013 | 4 | 85.0% | 10.13 | 11.92 | 354 | 807 | 2.0 | 12 | 9 | 4 | 46 | 270 | 83 | 22 | 52 | 1 | 422 |
| 46 | Rome OdunzeChicago Bears·#15 | 12 | 91 | 44 | 661 | 6 | 48.4% | 7.26 | 15.02 | 214 | 1,024 | 2.8 | 13 | 5 | 3 | 44 | 235 | 72 | 11 | 37 | 3 | 453 |
| 47 | Quentin JohnstonLos Angeles Chargers·#1 | 14 | 83 | 51 | 735 | 8 | 61.5% | 8.86 | 14.41 | 221 | 830 | 2.0 | 15 | 10 | 4 | 44 | 277 | 72 | 5 | 27 | 2 | 490 |
| 48 | Brandin CooksNew Orleans Saints·#18 | 10 | 25 | 19 | 165 | 0 | 76.0% | 6.60 | 8.68 | 37 | 219 | 0.8 | 1 | 0 | 0 | 44 | 188 | 21 | 13 | 10 | 4 | 300 |
| 49 | Darius SlaytonNew York Giants·#18 | 14 | 65 | 37 | 542 | 1 | 56.9% | 8.34 | 14.65 | 198 | 768 | 1.9 | 8 | 1 | 0 | 43 | 264 | 54 | 7 | 23 | 3 | 440 |
| 50 | Isaiah BondCleveland Browns·#16 | 16 | 43 | 18 | 344 | 0 | 41.9% | 8.00 | 19.11 | 58 | 661 | 2.0 | 4 | 1 | 0 | 43 | 183 | 33 | 6 | 11 | 3 | 347 |