| 1 | Ja'Marr ChaseCincinnati Bengals·#1 | 16 | 101 | 66 | 678 | 4 | 65.3% | 6.71 | 10.27 | 320 | 784 | 2.4 | 13 | 7 | 4 | 54 | 215 | 80 | 10 | 37 | 4 | 347 |
| 2 | Andrei IosivasCincinnati Bengals·#80 | 17 | 26 | 17 | 183 | 0 | 65.4% | 7.04 | 10.76 | 40 | 245 | 0.9 | 2 | 0 | 0 | 44 | 178 | 17 | 8 | 11 | 1 | 274 |
| 3 | Brian Thomas Jr.Jacksonville Jaguars·#7 | 14 | 49 | 32 | 408 | 2 | 65.3% | 8.33 | 12.75 | 75 | 602 | 2.4 | 2 | 1 | 1 | 42 | 177 | 42 | 6 | 21 | 1 | 272 |
| 4 | Justin JeffersonMinnesota Vikings·#18 | 17 | 81 | 55 | 703 | 1 | 67.9% | 8.68 | 12.78 | 341 | 594 | 1.9 | 10 | 2 | 1 | 42 | 172 | 60 | 11 | 35 | 2 | 315 |
| 5 | Jauan JenningsSan Francisco 49ers·#15 | 15 | 50 | 31 | 316 | 4 | 62.0% | 6.32 | 10.19 | 92 | 352 | 1.7 | 12 | 7 | 4 | 40 | 162 | 48 | 6 | 19 | 2 | 248 |
| 6 | George PickensDallas Cowboys·#3 | 17 | 72 | 49 | 686 | 5 | 68.1% | 9.53 | 14.00 | 195 | 706 | 2.7 | 13 | 4 | 3 | 39 | 219 | 67 | 7 | 39 | 3 | 319 |
| 7 | Michael WilsonArizona Cardinals·#14 | 17 | 57 | 39 | 476 | 4 | 68.4% | 8.35 | 12.21 | 119 | 518 | 2.0 | 7 | 4 | 2 | 39 | 175 | 53 | 8 | 26 | 4 | 294 |
| 8 | Michael PittmanIndianapolis Colts·#11 | 17 | 60 | 43 | 403 | 5 | 71.7% | 6.72 | 9.37 | 139 | 409 | 1.5 | 9 | 4 | 3 | 38 | 201 | 50 | 15 | 27 | 2 | 306 |
| 9 | Tre TuckerLas Vegas Raiders·#1 | 17 | 52 | 29 | 317 | 2 | 55.8% | 6.10 | 10.93 | 107 | 466 | 1.7 | 4 | 1 | 1 | 38 | 172 | 40 | 5 | 16 | 0 | 310 |
| 10 | Tee HigginsCincinnati Bengals·#5 | 15 | 49 | 31 | 471 | 7 | 63.3% | 9.61 | 15.19 | 93 | 584 | 2.6 | 10 | 7 | 2 | 36 | 179 | 45 | 9 | 21 | 3 | 274 |
| 11 | Alec PierceIndianapolis Colts·#14 | 15 | 45 | 28 | 584 | 6 | 62.2% | 12.98 | 20.86 | 92 | 802 | 3.3 | 6 | 4 | 4 | 36 | 170 | 44 | 14 | 25 | 2 | 273 |
| 12 | Courtland SuttonDenver Broncos·#14 | 17 | 62 | 38 | 538 | 6 | 61.3% | 8.68 | 14.16 | 128 | 550 | 2.3 | 9 | 4 | 3 | 35 | 203 | 57 | 2 | 27 | 2 | 314 |
| 13 | Chris OlaveNew Orleans Saints·#12 | 16 | 78 | 50 | 558 | 2 | 64.1% | 7.15 | 11.16 | 168 | 623 | 3.0 | 6 | 1 | 0 | 34 | 179 | 65 | 7 | 22 | 5 | 300 |
| 14 | Jordan AddisonMinnesota Vikings·#3 | 14 | 36 | 17 | 263 | 0 | 47.2% | 7.31 | 15.47 | 34 | 524 | 2.4 | 4 | 1 | 0 | 34 | 135 | 33 | 10 | 7 | 1 | 228 |
| 15 | Puka NacuaLos Angeles Rams·#12 | 16 | 85 | 66 | 905 | 4 | 77.7% | 10.65 | 13.71 | 320 | 828 | 3.2 | 9 | 6 | 1 | 33 | 171 | 71 | 8 | 43 | 1 | 258 |
| 16 | Darnell MooneyAtlanta Falcons·#1 | 15 | 34 | 16 | 223 | 0 | 47.1% | 6.56 | 13.94 | 24 | 390 | 1.9 | 5 | 2 | 0 | 33 | 148 | 31 | 7 | 13 | 3 | 249 |
| 17 | Davante AdamsLos Angeles Rams·#17 | 14 | 67 | 37 | 444 | 10 | 55.2% | 6.63 | 12.00 | 45 | 708 | 3.4 | 24 | 9 | 8 | 32 | 154 | 62 | 8 | 31 | 1 | 223 |
| 18 | DJ MooreChicago Bears·#2 | 17 | 44 | 22 | 269 | 2 | 50.0% | 6.11 | 12.23 | 138 | 318 | 1.4 | 6 | 4 | 2 | 31 | 163 | 25 | 7 | 14 | 1 | 307 |
| 19 | Marvin Harrison Jr.Arizona Cardinals·#18 | 12 | 39 | 23 | 355 | 2 | 59.0% | 9.10 | 15.43 | 60 | 471 | 2.2 | 4 | 3 | 2 | 31 | 131 | 36 | 5 | 18 | 3 | 217 |
| 20 | Romeo DoubsGreen Bay Packers·#87 | 16 | 59 | 35 | 486 | 4 | 59.3% | 8.24 | 13.89 | 114 | 635 | 3.1 | 12 | 6 | 4 | 30 | 145 | 51 | 7 | 29 | 3 | 250 |
| 21 | Keenan AllenLos Angeles Chargers·#13 | 17 | 61 | 41 | 399 | 1 | 67.2% | 6.54 | 9.73 | 106 | 465 | 2.3 | 5 | 3 | 1 | 30 | 134 | 51 | 3 | 21 | 2 | 237 |
| 22 | Drake LondonAtlanta Falcons·#5 | 12 | 65 | 45 | 603 | 6 | 69.2% | 9.28 | 13.40 | 172 | 671 | 3.3 | 7 | 7 | 6 | 29 | 134 | 63 | 7 | 30 | 3 | 221 |
| 23 | CeeDee LambDallas Cowboys·#88 | 14 | 62 | 43 | 608 | 3 | 69.3% | 9.81 | 14.14 | 226 | 650 | 2.6 | 8 | 5 | 2 | 29 | 167 | 53 | 3 | 27 | 3 | 258 |
| 24 | Josh DownsIndianapolis Colts·#2 | 16 | 55 | 37 | 363 | 1 | 67.3% | 6.60 | 9.81 | 95 | 332 | 1.8 | 6 | 3 | 1 | 29 | 146 | 53 | 9 | 22 | 2 | 226 |
| 25 | Ladd McConkeyLos Angeles Chargers·#15 | 16 | 61 | 39 | 426 | 4 | 63.9% | 6.98 | 10.92 | 148 | 455 | 2.0 | 9 | 4 | 2 | 28 | 173 | 50 | 4 | 20 | 3 | 297 |
| 26 | Jerry JeudyCleveland Browns·#3 | 17 | 59 | 33 | 444 | 2 | 55.9% | 7.53 | 13.45 | 124 | 622 | 2.5 | 4 | 1 | 0 | 28 | 153 | 54 | 3 | 20 | 1 | 265 |
| 27 | Nico CollinsHouston Texans·#12 | 15 | 69 | 43 | 685 | 3 | 62.3% | 9.93 | 15.93 | 212 | 857 | 3.4 | 8 | 4 | 1 | 28 | 162 | 61 | 4 | 30 | 0 | 272 |
| 28 | Ricky PearsallSan Francisco 49ers·#1 | 9 | 33 | 23 | 278 | 0 | 69.7% | 8.42 | 12.09 | 38 | 335 | 2.5 | 1 | 0 | 0 | 27 | 109 | 29 | 4 | 18 | 1 | 167 |
| 29 | Troy FranklinDenver Broncos·#11 | 17 | 61 | 36 | 358 | 3 | 59.0% | 5.87 | 9.94 | 143 | 500 | 3.1 | 7 | 5 | 2 | 27 | 168 | 39 | 2 | 18 | 2 | 260 |
| 30 | Kendrick BourneSan Francisco 49ers·#84 | 15 | 20 | 13 | 257 | 0 | 65.0% | 12.85 | 19.77 | 104 | 223 | 1.3 | 0 | 0 | 0 | 27 | 126 | 17 | 5 | 10 | 1 | 183 |
| 31 | Deebo Samuel Sr.Washington Commanders·#1 | 16 | 52 | 39 | 354 | 0 | 75.0% | 6.81 | 9.08 | 285 | 204 | 0.8 | 4 | 2 | 0 | 27 | 128 | 27 | 4 | 14 | 1 | 269 |
| 32 | Rome OdunzeChicago Bears·#15 | 12 | 53 | 26 | 380 | 3 | 49.1% | 7.17 | 14.62 | 125 | 568 | 3.1 | 7 | 2 | 1 | 26 | 128 | 42 | 5 | 21 | 2 | 247 |
| 33 | Wan'Dale RobinsonNew York Giants·#17 | 16 | 66 | 50 | 584 | 2 | 75.8% | 8.85 | 11.68 | 204 | 513 | 2.2 | 4 | 2 | 0 | 26 | 155 | 48 | 5 | 24 | 1 | 245 |
| 34 | Parker WashingtonJacksonville Jaguars·#11 | 16 | 46 | 31 | 434 | 4 | 67.4% | 9.43 | 14.00 | 87 | 541 | 2.8 | 9 | 7 | 3 | 26 | 131 | 37 | 4 | 19 | 2 | 215 |
| 35 | Jakobi MeyersJacksonville Jaguars·#3 | 10 | 38 | 24 | 282 | 2 | 63.2% | 7.42 | 11.75 | 64 | 310 | 1.9 | 4 | 3 | 2 | 25 | 108 | 34 | 6 | 16 | 2 | 186 |
| 36 | Jalen NailorMinnesota Vikings·#1 | 17 | 24 | 16 | 292 | 1 | 66.7% | 12.17 | 18.25 | 97 | 290 | 1.4 | 4 | 2 | 1 | 24 | 115 | 19 | 7 | 12 | 2 | 218 |
| 37 | Zay FlowersBaltimore Ravens·#4 | 17 | 57 | 41 | 514 | 1 | 71.9% | 9.02 | 12.54 | 167 | 552 | 2.1 | 5 | 3 | 0 | 24 | 154 | 42 | 6 | 23 | 4 | 269 |
| 38 | Stefon DiggsNew England Patriots·#8 | 17 | 49 | 41 | 440 | 3 | 83.7% | 8.98 | 10.73 | 160 | 382 | 1.8 | 8 | 5 | 3 | 24 | 145 | 42 | 12 | 23 | 1 | 222 |
| 39 | Jayden HigginsHouston Texans·#81 | 17 | 36 | 20 | 263 | 4 | 55.6% | 7.31 | 13.15 | 65 | 371 | 2.1 | 5 | 3 | 3 | 24 | 136 | 33 | 5 | 13 | 0 | 211 |
| 40 | DK MetcalfPittsburgh Steelers·#4 | 15 | 57 | 32 | 517 | 4 | 56.1% | 9.07 | 16.16 | 267 | 540 | 2.0 | 11 | 7 | 3 | 24 | 157 | 49 | 9 | 21 | 0 | 292 |
| 41 | Christian WatsonGreen Bay Packers·#9 | 10 | 29 | 18 | 267 | 3 | 62.1% | 9.21 | 14.83 | 46 | 434 | 2.8 | 5 | 2 | 1 | 24 | 86 | 27 | 5 | 13 | 1 | 157 |
| 42 | Cooper KuppSeattle Seahawks·#10 | 16 | 30 | 22 | 297 | 0 | 73.3% | 9.90 | 13.50 | 172 | 144 | 0.9 | 4 | 3 | 0 | 23 | 131 | 25 | 5 | 12 | 3 | 211 |
| 43 | Quentin JohnstonLos Angeles Chargers·#1 | 14 | 46 | 32 | 460 | 6 | 69.6% | 10.00 | 14.38 | 172 | 408 | 1.6 | 10 | 6 | 3 | 23 | 151 | 38 | 4 | 16 | 2 | 266 |
| 44 | Emeka EgbukaTampa Bay Buccaneers·#2 | 17 | 60 | 33 | 379 | 3 | 55.0% | 6.32 | 11.48 | 179 | 398 | 2.1 | 4 | 2 | 1 | 22 | 158 | 46 | 4 | 16 | 2 | 264 |
| 45 | Jaxon Smith-NjigbaSeattle Seahawks·#11 | 17 | 85 | 63 | 913 | 6 | 74.1% | 10.74 | 14.49 | 230 | 911 | 3.8 | 9 | 5 | 3 | 22 | 161 | 76 | 6 | 36 | 3 | 246 |
| 46 | Mack HollinsNew England Patriots·#13 | 15 | 34 | 25 | 255 | 1 | 73.5% | 7.50 | 10.20 | 38 | 382 | 2.3 | 2 | 2 | 1 | 22 | 110 | 32 | 7 | 14 | 3 | 179 |
| 47 | Dont'e Thornton Jr.Las Vegas Raiders·#10 | 13 | 15 | 4 | 47 | 0 | 26.7% | 3.13 | 11.75 | 16 | 228 | 1.9 | 0 | 0 | 0 | 22 | 83 | 15 | 3 | 3 | 0 | 142 |
| 48 | Tetairoa McMillanCarolina Panthers·#4 | 17 | 72 | 42 | 598 | 3 | 58.3% | 8.31 | 14.24 | 163 | 681 | 2.8 | 11 | 7 | 2 | 22 | 163 | 67 | 6 | 34 | 3 | 265 |
| 49 | Brandin CooksNew Orleans Saints·#18 | 10 | 9 | 8 | 73 | 0 | 88.9% | 8.11 | 9.12 | 19 | 76 | 0.5 | 0 | 0 | 0 | 21 | 92 | 8 | 5 | 3 | 2 | 145 |
| 50 | Jameson WilliamsDetroit Lions·#1 | 17 | 45 | 29 | 471 | 4 | 64.4% | 10.47 | 16.24 | 148 | 636 | 2.0 | 1 | 0 | 0 | 21 | 215 | 41 | 5 | 23 | 2 | 315 |