| 1 | Alec PierceIndianapolis Colts·#14 | 15 | 67 | 42 | 924 | 5 | 62.7% | 13.79 | 22.00 | 151 | 1,179 | 3.4 | 6 | 3 | 3 | 56 | 237 | 64 | 17 | 36 | 3 | 372 |
| 2 | Stefon DiggsNew England Patriots·#8 | 17 | 71 | 63 | 767 | 1 | 88.7% | 10.80 | 12.17 | 224 | 626 | 2.2 | 8 | 6 | 1 | 34 | 201 | 57 | 17 | 32 | 1 | 299 |
| 3 | Michael PittmanIndianapolis Colts·#11 | 17 | 82 | 60 | 644 | 3 | 73.2% | 7.85 | 10.73 | 212 | 688 | 1.8 | 6 | 2 | 1 | 58 | 277 | 73 | 17 | 30 | 4 | 416 |
| 4 | Justin JeffersonMinnesota Vikings·#18 | 17 | 106 | 67 | 829 | 1 | 63.2% | 7.82 | 12.37 | 393 | 936 | 2.4 | 10 | 4 | 1 | 52 | 235 | 82 | 16 | 35 | 4 | 435 |
| 5 | Jordan AddisonMinnesota Vikings·#3 | 14 | 57 | 30 | 498 | 1 | 52.6% | 8.74 | 16.60 | 127 | 790 | 2.4 | 5 | 2 | 1 | 41 | 191 | 52 | 15 | 16 | 1 | 339 |
| 6 | Kayshon BoutteNew England Patriots·#9 | 14 | 37 | 28 | 502 | 4 | 75.7% | 13.57 | 17.93 | 33 | 646 | 2.5 | 0 | 0 | 0 | 30 | 176 | 36 | 15 | 22 | 1 | 278 |
| 7 | Ja'Marr ChaseCincinnati Bengals·#1 | 16 | 141 | 96 | 1,098 | 5 | 68.1% | 7.79 | 11.44 | 538 | 1,022 | 2.2 | 14 | 9 | 4 | 67 | 320 | 103 | 14 | 50 | 4 | 502 |
| 8 | DJ MooreChicago Bears·#2 | 17 | 63 | 38 | 513 | 2 | 60.3% | 8.14 | 13.50 | 173 | 615 | 1.6 | 5 | 2 | 0 | 39 | 249 | 37 | 14 | 20 | 2 | 459 |
| 9 | Chris OlaveNew Orleans Saints·#12 | 16 | 116 | 74 | 881 | 4 | 63.8% | 7.59 | 11.91 | 236 | 996 | 3.0 | 6 | 3 | 2 | 49 | 296 | 99 | 13 | 30 | 7 | 466 |
| 10 | Andrei IosivasCincinnati Bengals·#80 | 17 | 45 | 26 | 330 | 2 | 57.8% | 7.33 | 12.69 | 78 | 410 | 1.1 | 4 | 2 | 1 | 56 | 277 | 35 | 13 | 17 | 1 | 427 |
| 11 | Puka NacuaLos Angeles Rams·#12 | 16 | 120 | 92 | 1,294 | 6 | 76.7% | 10.78 | 14.07 | 493 | 1,232 | 3.8 | 7 | 6 | 1 | 33 | 229 | 96 | 12 | 50 | 3 | 332 |
| 12 | Mack HollinsNew England Patriots·#13 | 15 | 52 | 38 | 493 | 1 | 73.1% | 9.48 | 12.97 | 100 | 656 | 2.7 | 3 | 3 | 1 | 29 | 166 | 47 | 12 | 21 | 3 | 262 |
| 13 | Josh DownsIndianapolis Colts·#2 | 16 | 61 | 42 | 433 | 1 | 68.8% | 7.10 | 10.31 | 111 | 378 | 1.6 | 9 | 6 | 1 | 46 | 185 | 57 | 12 | 21 | 4 | 302 |
| 14 | Michael WilsonArizona Cardinals·#14 | 17 | 80 | 48 | 590 | 4 | 60.0% | 7.38 | 12.29 | 167 | 740 | 1.9 | 10 | 5 | 3 | 65 | 290 | 74 | 12 | 25 | 6 | 485 |
| 15 | Zay FlowersBaltimore Ravens·#4 | 17 | 92 | 68 | 935 | 3 | 73.9% | 10.16 | 13.75 | 374 | 907 | 2.3 | 6 | 5 | 1 | 32 | 239 | 67 | 12 | 34 | 7 | 398 |
| 16 | DeVonta SmithPhiladelphia Eagles·#6 | 17 | 83 | 54 | 695 | 1 | 65.1% | 8.37 | 12.87 | 190 | 875 | 2.3 | 6 | 2 | 0 | 46 | 245 | 68 | 11 | 26 | 4 | 446 |
| 17 | A.J. BrownPhiladelphia Eagles·#11 | 15 | 92 | 59 | 759 | 3 | 64.1% | 8.25 | 12.86 | 207 | 926 | 2.8 | 9 | 6 | 1 | 46 | 233 | 81 | 11 | 30 | 4 | 404 |
| 18 | Jaxon Smith-NjigbaSeattle Seahawks·#11 | 17 | 127 | 93 | 1,344 | 5 | 73.2% | 10.58 | 14.45 | 403 | 1,373 | 3.7 | 11 | 6 | 2 | 24 | 253 | 110 | 11 | 55 | 6 | 386 |
| 19 | Wan'Dale RobinsonNew York Giants·#17 | 16 | 105 | 72 | 707 | 1 | 68.6% | 6.73 | 9.82 | 332 | 765 | 2.1 | 7 | 3 | 0 | 50 | 240 | 73 | 10 | 20 | 3 | 413 |
| 20 | Malik WashingtonMiami Dolphins·#6 | 17 | 46 | 34 | 218 | 2 | 73.9% | 4.74 | 6.41 | 188 | 138 | 0.7 | 6 | 5 | 2 | 27 | 163 | 23 | 10 | 7 | 2 | 289 |
| 21 | DK MetcalfPittsburgh Steelers·#4 | 15 | 70 | 45 | 684 | 4 | 64.3% | 9.77 | 15.20 | 340 | 636 | 1.7 | 5 | 5 | 1 | 34 | 229 | 61 | 10 | 24 | 4 | 401 |
| 22 | Cooper KuppSeattle Seahawks·#10 | 16 | 54 | 36 | 444 | 1 | 66.7% | 8.22 | 12.33 | 211 | 361 | 1.3 | 9 | 5 | 1 | 25 | 215 | 46 | 10 | 16 | 6 | 332 |
| 23 | Jalen NailorMinnesota Vikings·#1 | 17 | 29 | 19 | 286 | 2 | 65.5% | 9.86 | 15.05 | 68 | 337 | 1.1 | 5 | 4 | 2 | 34 | 176 | 22 | 10 | 13 | 3 | 325 |
| 24 | George PickensDallas Cowboys·#3 | 17 | 89 | 55 | 856 | 4 | 61.8% | 9.62 | 15.56 | 278 | 942 | 2.5 | 14 | 6 | 1 | 53 | 299 | 83 | 9 | 35 | 5 | 439 |
| 25 | Darnell MooneyAtlanta Falcons·#1 | 15 | 57 | 25 | 371 | 1 | 43.9% | 6.51 | 14.84 | 64 | 614 | 2.5 | 3 | 1 | 0 | 44 | 213 | 54 | 9 | 18 | 4 | 359 |
| 26 | Brandin CooksNew Orleans Saints·#18 | 10 | 15 | 11 | 98 | 0 | 73.3% | 6.53 | 8.91 | 35 | 115 | 0.6 | 1 | 0 | 0 | 28 | 147 | 12 | 9 | 5 | 4 | 220 |
| 27 | Davante AdamsLos Angeles Rams·#17 | 14 | 61 | 36 | 587 | 3 | 59.0% | 9.62 | 16.31 | 93 | 867 | 3.5 | 8 | 2 | 1 | 28 | 197 | 61 | 9 | 27 | 4 | 271 |
| 28 | Tee HigginsCincinnati Bengals·#5 | 15 | 66 | 40 | 563 | 4 | 60.6% | 8.53 | 14.08 | 97 | 740 | 2.3 | 8 | 7 | 2 | 48 | 257 | 60 | 9 | 22 | 3 | 397 |
| 29 | Rome OdunzeChicago Bears·#15 | 12 | 65 | 31 | 538 | 3 | 47.7% | 8.28 | 17.35 | 174 | 795 | 3.0 | 5 | 1 | 0 | 29 | 173 | 54 | 9 | 26 | 3 | 333 |
| 30 | Jerry JeudyCleveland Browns·#3 | 17 | 84 | 39 | 474 | 2 | 46.4% | 5.64 | 12.15 | 149 | 958 | 2.2 | 5 | 1 | 0 | 55 | 266 | 76 | 9 | 22 | 3 | 474 |
| 31 | Drake LondonAtlanta Falcons·#5 | 12 | 80 | 51 | 737 | 3 | 63.8% | 9.21 | 14.45 | 177 | 831 | 3.1 | 7 | 4 | 3 | 34 | 177 | 76 | 9 | 32 | 3 | 305 |
| 32 | Courtland SuttonDenver Broncos·#14 | 17 | 78 | 50 | 661 | 4 | 64.1% | 8.47 | 13.22 | 125 | 728 | 2.2 | 11 | 4 | 2 | 42 | 300 | 68 | 8 | 31 | 2 | 456 |
| 33 | Tre TuckerLas Vegas Raiders·#1 | 17 | 77 | 50 | 558 | 3 | 64.9% | 7.25 | 11.16 | 245 | 694 | 1.7 | 8 | 5 | 2 | 46 | 280 | 60 | 8 | 25 | 1 | 449 |
| 34 | Rashod BatemanBaltimore Ravens·#7 | 13 | 27 | 15 | 202 | 1 | 55.6% | 7.48 | 13.47 | 39 | 354 | 1.4 | 5 | 3 | 1 | 20 | 170 | 23 | 8 | 9 | 5 | 255 |
| 35 | Jayden HigginsHouston Texans·#81 | 17 | 44 | 29 | 298 | 4 | 65.9% | 6.77 | 10.28 | 39 | 479 | 1.8 | 7 | 5 | 4 | 31 | 174 | 41 | 8 | 16 | 0 | 267 |
| 36 | Brian Thomas Jr.Jacksonville Jaguars·#7 | 14 | 69 | 35 | 548 | 1 | 50.7% | 7.94 | 15.66 | 135 | 935 | 2.9 | 5 | 1 | 0 | 50 | 238 | 61 | 8 | 22 | 1 | 370 |
| 37 | Rashid ShaheedNew Orleans Saints·#22 | 9 | 52 | 36 | 424 | 1 | 69.2% | 8.15 | 11.78 | 135 | 476 | 2.6 | 4 | 4 | 0 | 29 | 151 | 41 | 8 | 14 | 4 | 241 |
| 38 | Nico CollinsHouston Texans·#12 | 15 | 95 | 56 | 947 | 4 | 59.0% | 9.97 | 16.91 | 269 | 1,205 | 3.8 | 11 | 6 | 1 | 37 | 219 | 84 | 8 | 35 | 1 | 351 |
| 39 | Romeo DoubsGreen Bay Packers·#87 | 16 | 63 | 41 | 608 | 1 | 65.1% | 9.65 | 14.83 | 134 | 739 | 2.8 | 7 | 5 | 1 | 33 | 193 | 53 | 7 | 28 | 3 | 324 |
| 40 | Parker WashingtonJacksonville Jaguars·#11 | 16 | 65 | 44 | 612 | 3 | 67.7% | 9.42 | 13.91 | 158 | 759 | 2.6 | 8 | 6 | 2 | 35 | 194 | 55 | 7 | 26 | 2 | 321 |
| 41 | David SillsAtlanta Falcons·#87 | 17 | 31 | 16 | 161 | 2 | 51.6% | 5.19 | 10.06 | 53 | 267 | 1.2 | 5 | 3 | 2 | 35 | 161 | 25 | 7 | 7 | 3 | 277 |
| 42 | Darius SlaytonNew York Giants·#18 | 14 | 49 | 29 | 438 | 1 | 59.2% | 8.94 | 15.10 | 170 | 624 | 2.0 | 4 | 1 | 0 | 32 | 197 | 42 | 7 | 15 | 3 | 335 |
| 43 | Chimere DikeTennessee Titans·#17 | 17 | 53 | 32 | 260 | 1 | 60.4% | 4.91 | 8.12 | 132 | 378 | 1.2 | 10 | 6 | 0 | 27 | 180 | 28 | 7 | 8 | 4 | 335 |
| 44 | Dont'e Thornton Jr.Las Vegas Raiders·#10 | 14 | 21 | 7 | 99 | 0 | 33.3% | 4.71 | 14.14 | 19 | 298 | 1.7 | 1 | 0 | 0 | 29 | 120 | 19 | 7 | 4 | 1 | 193 |
| 45 | Jakobi MeyersJacksonville Jaguars·#3 | 10 | 49 | 34 | 365 | 1 | 69.4% | 7.45 | 10.74 | 122 | 388 | 1.7 | 4 | 3 | 1 | 31 | 152 | 42 | 7 | 18 | 1 | 247 |
| 46 | Jalen TolbertDallas Cowboys·#1 | 13 | 19 | 8 | 120 | 1 | 42.1% | 6.32 | 15.00 | 19 | 247 | 1.6 | 3 | 0 | 0 | 25 | 122 | 14 | 6 | 4 | 1 | 183 |
| 47 | Jaylen WaddleMiami Dolphins·#17 | 16 | 73 | 50 | 777 | 3 | 68.5% | 10.64 | 15.54 | 188 | 884 | 3.3 | 2 | 2 | 0 | 26 | 195 | 68 | 6 | 36 | 2 | 308 |
| 48 | Marvin Mims Jr.Denver Broncos·#19 | 15 | 44 | 32 | 290 | 1 | 72.7% | 6.59 | 9.06 | 198 | 294 | 2.0 | 3 | 2 | 0 | 20 | 148 | 23 | 6 | 12 | 1 | 226 |
| 49 | Khalil ShakirBuffalo Bills·#10 | 16 | 60 | 48 | 520 | 1 | 80.0% | 8.67 | 10.83 | 374 | 177 | 0.7 | 4 | 4 | 0 | 36 | 191 | 35 | 6 | 15 | 1 | 302 |
| 50 | Kyle WilliamsNew England Patriots·#18 | 17 | 14 | 8 | 187 | 3 | 57.1% | 13.36 | 23.38 | 66 | 296 | 2.2 | 0 | 0 | 0 | 19 | 90 | 14 | 6 | 5 | 0 | 142 |