| 1 | Ja'Marr ChaseCincinnati Bengals·#1 | 16 | 110 | 77 | 893 | 3 | 70.0% | 8.12 | 11.60 | 439 | 782 | 2.2 | 9 | 6 | 2 | 47 | 253 | 76 | 12 | 37 | 4 | 395 |
| 2 | Jaxon Smith-NjigbaSeattle Seahawks·#11 | 17 | 101 | 75 | 1,121 | 5 | 74.3% | 11.10 | 14.95 | 353 | 1,128 | 3.9 | 8 | 5 | 2 | 16 | 200 | 88 | 8 | 43 | 4 | 297 |
| 3 | Puka NacuaLos Angeles Rams·#12 | 16 | 96 | 74 | 1,063 | 5 | 77.1% | 11.07 | 14.36 | 405 | 990 | 3.8 | 5 | 4 | 1 | 25 | 184 | 76 | 10 | 39 | 3 | 267 |
| 4 | Amon-Ra St. BrownDetroit Lions·#14 | 16 | 90 | 64 | 827 | 3 | 71.1% | 9.19 | 12.92 | 331 | 771 | 2.5 | 9 | 6 | 3 | 20 | 227 | 79 | 4 | 31 | 2 | 334 |
| 5 | Wan'Dale RobinsonNew York Giants·#17 | 16 | 81 | 62 | 581 | 0 | 76.5% | 7.17 | 9.37 | 274 | 499 | 1.8 | 4 | 3 | 0 | 33 | 194 | 53 | 8 | 14 | 3 | 324 |
| 6 | Justin JeffersonMinnesota Vikings·#18 | 17 | 85 | 60 | 751 | 1 | 70.6% | 8.84 | 12.52 | 355 | 796 | 2.7 | 6 | 4 | 1 | 36 | 180 | 65 | 12 | 30 | 4 | 329 |
| 7 | Zay FlowersBaltimore Ravens·#4 | 17 | 76 | 59 | 806 | 2 | 77.6% | 10.61 | 13.66 | 302 | 769 | 2.5 | 4 | 4 | 0 | 24 | 191 | 53 | 8 | 27 | 5 | 309 |
| 8 | Michael PittmanIndianapolis Colts·#11 | 17 | 71 | 54 | 570 | 2 | 76.1% | 8.03 | 10.56 | 193 | 576 | 2.0 | 4 | 1 | 0 | 36 | 215 | 64 | 14 | 25 | 4 | 325 |
| 9 | Chris OlaveNew Orleans Saints·#12 | 16 | 87 | 54 | 602 | 2 | 62.1% | 6.92 | 11.15 | 155 | 682 | 2.9 | 3 | 1 | 1 | 40 | 225 | 71 | 6 | 17 | 5 | 359 |
| 10 | Deebo Samuel Sr.Washington Commanders·#1 | 16 | 61 | 50 | 541 | 2 | 82.0% | 8.87 | 10.82 | 388 | 290 | 0.9 | 5 | 4 | 2 | 30 | 146 | 30 | 2 | 20 | 3 | 309 |
| 11 | George PickensDallas Cowboys·#3 | 17 | 74 | 47 | 757 | 4 | 63.5% | 10.23 | 16.11 | 219 | 847 | 2.9 | 9 | 5 | 1 | 38 | 224 | 68 | 5 | 30 | 5 | 336 |
| 12 | A.J. BrownPhiladelphia Eagles·#11 | 15 | 71 | 47 | 609 | 2 | 66.2% | 8.58 | 12.96 | 149 | 706 | 2.7 | 5 | 4 | 0 | 36 | 188 | 62 | 11 | 23 | 2 | 325 |
| 13 | Stefon DiggsNew England Patriots·#8 | 17 | 47 | 44 | 585 | 1 | 93.6% | 12.45 | 13.30 | 192 | 439 | 2.1 | 3 | 2 | 1 | 21 | 152 | 37 | 14 | 25 | 1 | 216 |
| 14 | DeVonta SmithPhiladelphia Eagles·#6 | 17 | 64 | 44 | 617 | 1 | 68.8% | 9.64 | 14.02 | 167 | 719 | 2.3 | 5 | 2 | 0 | 36 | 198 | 51 | 11 | 22 | 2 | 363 |
| 15 | Ladd McConkeyLos Angeles Chargers·#15 | 16 | 65 | 43 | 558 | 3 | 66.2% | 8.58 | 12.98 | 196 | 544 | 2.6 | 7 | 4 | 1 | 28 | 172 | 54 | 2 | 18 | 1 | 291 |
| 16 | Troy FranklinDenver Broncos·#11 | 17 | 64 | 41 | 465 | 2 | 64.1% | 7.27 | 11.34 | 180 | 621 | 3.0 | 5 | 5 | 0 | 24 | 205 | 41 | 5 | 16 | 0 | 297 |
| 17 | Michael WilsonArizona Cardinals·#14 | 17 | 65 | 41 | 520 | 4 | 63.1% | 8.00 | 12.68 | 135 | 608 | 2.1 | 7 | 4 | 3 | 47 | 237 | 61 | 9 | 21 | 4 | 386 |
| 18 | Tre TuckerLas Vegas Raiders·#1 | 17 | 63 | 40 | 445 | 2 | 63.5% | 7.06 | 11.12 | 181 | 561 | 1.6 | 6 | 3 | 1 | 36 | 233 | 49 | 8 | 19 | 1 | 371 |
| 19 | Emeka EgbukaTampa Bay Buccaneers·#2 | 17 | 73 | 40 | 685 | 4 | 54.8% | 9.38 | 17.12 | 233 | 823 | 3.6 | 4 | 2 | 1 | 24 | 185 | 63 | 6 | 19 | 3 | 297 |
| 20 | Drake LondonAtlanta Falcons·#5 | 12 | 59 | 39 | 587 | 1 | 66.1% | 9.95 | 15.05 | 150 | 618 | 3.0 | 4 | 2 | 1 | 23 | 139 | 55 | 5 | 22 | 2 | 231 |
| 21 | Jaylen WaddleMiami Dolphins·#17 | 16 | 57 | 39 | 638 | 2 | 68.4% | 11.19 | 16.36 | 143 | 702 | 3.5 | 1 | 1 | 0 | 18 | 148 | 53 | 4 | 29 | 1 | 230 |
| 22 | Jameson WilliamsDetroit Lions·#1 | 17 | 58 | 39 | 616 | 3 | 67.2% | 10.62 | 15.79 | 216 | 768 | 2.1 | 5 | 2 | 1 | 20 | 241 | 49 | 4 | 26 | 2 | 360 |
| 23 | DK MetcalfPittsburgh Steelers·#4 | 15 | 59 | 38 | 617 | 3 | 64.4% | 10.46 | 16.24 | 302 | 564 | 1.8 | 2 | 2 | 0 | 23 | 188 | 51 | 9 | 19 | 3 | 331 |
| 24 | Courtland SuttonDenver Broncos·#14 | 17 | 59 | 38 | 528 | 3 | 64.4% | 8.95 | 13.89 | 85 | 586 | 2.1 | 8 | 2 | 1 | 32 | 247 | 53 | 6 | 22 | 0 | 365 |
| 25 | CeeDee LambDallas Cowboys·#88 | 14 | 57 | 37 | 563 | 3 | 64.9% | 9.88 | 15.22 | 172 | 647 | 2.9 | 6 | 3 | 2 | 28 | 165 | 50 | 3 | 17 | 4 | 252 |
| 26 | Nico CollinsHouston Texans·#12 | 15 | 68 | 37 | 635 | 3 | 54.4% | 9.34 | 17.16 | 130 | 924 | 3.9 | 8 | 3 | 1 | 25 | 165 | 63 | 7 | 22 | 1 | 266 |
| 27 | Keenan AllenLos Angeles Chargers·#13 | 17 | 50 | 34 | 321 | 0 | 68.0% | 6.42 | 9.44 | 91 | 422 | 2.1 | 3 | 0 | 0 | 26 | 141 | 43 | 2 | 9 | 1 | 231 |
| 28 | DJ MooreChicago Bears·#2 | 17 | 54 | 34 | 489 | 2 | 63.0% | 9.06 | 14.38 | 152 | 548 | 1.7 | 5 | 2 | 0 | 30 | 206 | 32 | 13 | 19 | 2 | 381 |
| 29 | Khalil ShakirBuffalo Bills·#10 | 16 | 42 | 34 | 363 | 0 | 81.0% | 8.64 | 10.68 | 212 | 125 | 0.8 | 1 | 1 | 0 | 25 | 137 | 27 | 5 | 9 | 1 | 215 |
| 30 | Tetairoa McMillanCarolina Panthers·#4 | 17 | 58 | 34 | 506 | 2 | 58.6% | 8.72 | 14.88 | 134 | 625 | 2.5 | 2 | 2 | 1 | 27 | 167 | 48 | 2 | 24 | 4 | 281 |
| 31 | Luther Burden IIIChicago Bears·#10 | 15 | 38 | 32 | 499 | 2 | 84.2% | 13.13 | 15.59 | 260 | 286 | 1.9 | 2 | 1 | 0 | 8 | 101 | 25 | 4 | 17 | 2 | 164 |
| 32 | Jauan JenningsSan Francisco 49ers·#15 | 15 | 50 | 32 | 395 | 3 | 64.0% | 7.90 | 12.34 | 98 | 504 | 2.2 | 7 | 4 | 1 | 39 | 177 | 46 | 6 | 18 | 5 | 249 |
| 33 | Alec PierceIndianapolis Colts·#14 | 15 | 51 | 31 | 715 | 2 | 60.8% | 14.02 | 23.06 | 90 | 990 | 3.6 | 2 | 1 | 1 | 34 | 184 | 50 | 14 | 27 | 3 | 288 |
| 34 | Josh DownsIndianapolis Colts·#2 | 16 | 42 | 31 | 338 | 0 | 73.8% | 8.05 | 10.90 | 73 | 302 | 1.8 | 4 | 3 | 0 | 26 | 130 | 39 | 9 | 15 | 4 | 224 |
| 35 | Xavier WorthyKansas City Chiefs·#1 | 13 | 48 | 30 | 312 | 0 | 62.5% | 6.50 | 10.40 | 134 | 452 | 2.0 | 3 | 3 | 0 | 11 | 143 | 40 | 2 | 11 | 0 | 269 |
| 36 | Davante AdamsLos Angeles Rams·#17 | 14 | 51 | 30 | 513 | 3 | 58.8% | 10.06 | 17.10 | 75 | 806 | 3.8 | 5 | 2 | 1 | 22 | 161 | 51 | 8 | 23 | 4 | 220 |
| 37 | Rashee RiceKansas City Chiefs·#4 | 8 | 39 | 29 | 388 | 1 | 74.4% | 9.95 | 13.38 | 259 | 196 | 1.4 | 4 | 2 | 0 | 8 | 85 | 21 | 2 | 12 | 0 | 155 |
| 38 | Tee HigginsCincinnati Bengals·#5 | 15 | 48 | 29 | 396 | 3 | 60.4% | 8.25 | 13.66 | 67 | 545 | 2.1 | 4 | 4 | 1 | 34 | 209 | 43 | 9 | 14 | 3 | 316 |
| 39 | Quentin JohnstonLos Angeles Chargers·#1 | 14 | 46 | 29 | 365 | 3 | 63.0% | 7.93 | 12.59 | 106 | 492 | 2.2 | 5 | 4 | 1 | 22 | 155 | 39 | 2 | 12 | 1 | 268 |
| 40 | Parker WashingtonJacksonville Jaguars·#11 | 16 | 45 | 29 | 400 | 1 | 64.4% | 8.89 | 13.79 | 89 | 592 | 2.7 | 5 | 3 | 0 | 26 | 150 | 37 | 5 | 15 | 2 | 248 |
| 41 | Marquise BrownKansas City Chiefs·#5 | 16 | 40 | 28 | 366 | 1 | 70.0% | 9.15 | 13.07 | 117 | 353 | 1.9 | 3 | 2 | 1 | 11 | 139 | 32 | 3 | 15 | 0 | 240 |
| 42 | Mack HollinsNew England Patriots·#13 | 15 | 41 | 28 | 399 | 0 | 68.3% | 9.73 | 14.25 | 88 | 574 | 3.1 | 2 | 2 | 0 | 21 | 132 | 38 | 11 | 17 | 3 | 201 |
| 43 | Jakobi MeyersJacksonville Jaguars·#3 | 10 | 40 | 28 | 306 | 1 | 70.0% | 7.65 | 10.93 | 93 | 357 | 1.9 | 3 | 3 | 1 | 22 | 120 | 35 | 5 | 13 | 1 | 193 |
| 44 | Jerry JeudyCleveland Browns·#3 | 17 | 64 | 28 | 370 | 2 | 43.8% | 5.78 | 13.21 | 119 | 724 | 2.2 | 3 | 0 | 0 | 43 | 205 | 56 | 6 | 16 | 3 | 366 |
| 45 | Cooper KuppSeattle Seahawks·#10 | 16 | 38 | 28 | 363 | 1 | 73.7% | 9.55 | 12.96 | 175 | 249 | 1.2 | 3 | 3 | 1 | 17 | 170 | 30 | 7 | 13 | 4 | 254 |
| 46 | Brian Thomas Jr.Jacksonville Jaguars·#7 | 14 | 53 | 27 | 434 | 1 | 50.9% | 8.19 | 16.07 | 120 | 732 | 2.8 | 2 | 1 | 0 | 39 | 186 | 46 | 6 | 16 | 1 | 290 |
| 47 | Kendrick BourneSan Francisco 49ers·#84 | 16 | 36 | 25 | 408 | 0 | 69.4% | 11.33 | 16.32 | 127 | 384 | 2.1 | 0 | 0 | 0 | 27 | 152 | 28 | 4 | 17 | 4 | 208 |
| 48 | Rashid ShaheedNew Orleans Saints·#22 | 9 | 36 | 25 | 343 | 1 | 69.4% | 9.53 | 13.72 | 113 | 391 | 3.0 | 1 | 1 | 0 | 22 | 104 | 29 | 4 | 10 | 4 | 174 |
| 49 | Garrett WilsonNew York Jets·#5 | 7 | 40 | 25 | 315 | 3 | 62.5% | 7.88 | 12.60 | 64 | 386 | 2.8 | 1 | 1 | 1 | 14 | 79 | 34 | 4 | 13 | 1 | 140 |
| 50 | Darius SlaytonNew York Giants·#18 | 14 | 36 | 24 | 405 | 1 | 66.7% | 11.25 | 16.88 | 166 | 444 | 1.9 | 1 | 0 | 0 | 21 | 161 | 32 | 6 | 14 | 3 | 269 |