| 1 | Davante AdamsLos Angeles Rams·#17 | 12 | 56 | 28 | 305 | 9 | 50.0% | 5.45 | 10.89 | 43 | 630 | 3.8 | 17 | 8 | 8 | 31 | 124 | 52 | 6 | 23 | 2 | 186 |
| 2 | Amon-Ra St. BrownDetroit Lions·#14 | 10 | 58 | 46 | 487 | 6 | 79.3% | 8.40 | 10.59 | 238 | 325 | 1.9 | 11 | 8 | 6 | 13 | 130 | 52 | 1 | 26 | 2 | 190 |
| 3 | Puka NacuaLos Angeles Rams·#12 | 13 | 60 | 47 | 673 | 5 | 78.3% | 11.22 | 14.32 | 260 | 494 | 2.8 | 3 | 2 | 1 | 22 | 117 | 52 | 5 | 30 | 1 | 185 |
| 4 | DK MetcalfPittsburgh Steelers·#4 | 14 | 38 | 25 | 432 | 5 | 65.8% | 11.37 | 17.28 | 215 | 471 | 2.1 | 4 | 3 | 2 | 17 | 129 | 31 | 5 | 17 | 2 | 229 |
| 5 | Michael PittmanIndianapolis Colts·#11 | 13 | 47 | 34 | 347 | 5 | 72.3% | 7.38 | 10.21 | 117 | 303 | 1.5 | 11 | 5 | 3 | 26 | 144 | 42 | 11 | 21 | 1 | 213 |
| 6 | Jaxon Smith-NjigbaSeattle Seahawks·#11 | 14 | 72 | 53 | 806 | 4 | 73.6% | 11.19 | 15.21 | 227 | 810 | 3.9 | 8 | 5 | 3 | 14 | 136 | 61 | 6 | 42 | 6 | 210 |
| 7 | Jauan JenningsSan Francisco 49ers·#15 | 10 | 38 | 25 | 328 | 4 | 65.8% | 8.63 | 13.12 | 96 | 292 | 2.0 | 8 | 4 | 3 | 27 | 133 | 35 | 1 | 18 | 3 | 180 |
| 8 | Marquise BrownKansas City Chiefs·#5 | 9 | 19 | 12 | 106 | 4 | 63.2% | 5.58 | 8.83 | 39 | 146 | 1.7 | 5 | 4 | 4 | 2 | 54 | 17 | 1 | 8 | 0 | 89 |
| 9 | Kayshon BoutteNew England Patriots·#9 | 12 | 19 | 15 | 210 | 4 | 79.0% | 11.05 | 14.00 | 11 | 299 | 1.7 | 2 | 2 | 2 | 21 | 108 | 18 | 11 | 12 | 0 | 175 |
| 10 | Stefon DiggsNew England Patriots·#8 | 15 | 51 | 45 | 577 | 3 | 88.2% | 11.31 | 12.82 | 207 | 464 | 2.3 | 8 | 8 | 3 | 24 | 135 | 42 | 11 | 27 | 1 | 210 |
| 11 | Zay FlowersBaltimore Ravens·#4 | 13 | 44 | 32 | 425 | 3 | 72.7% | 9.66 | 13.28 | 154 | 404 | 2.5 | 7 | 4 | 1 | 16 | 93 | 33 | 4 | 19 | 2 | 168 |
| 12 | Jameson WilliamsDetroit Lions·#1 | 10 | 35 | 21 | 420 | 3 | 60.0% | 12.00 | 20.00 | 179 | 591 | 3.0 | 3 | 2 | 1 | 13 | 134 | 31 | 1 | 15 | 2 | 196 |
| 13 | DJ MooreChicago Bears·#2 | 12 | 30 | 21 | 291 | 3 | 70.0% | 9.70 | 13.86 | 84 | 305 | 1.8 | 5 | 3 | 2 | 13 | 98 | 24 | 6 | 17 | 0 | 206 |
| 14 | Romeo DoubsGreen Bay Packers·#87 | 12 | 30 | 16 | 243 | 3 | 53.3% | 8.10 | 15.19 | 70 | 376 | 2.4 | 9 | 5 | 2 | 25 | 98 | 27 | 5 | 13 | 2 | 189 |
| 15 | Ladd McConkeyLos Angeles Chargers·#15 | 12 | 36 | 21 | 301 | 3 | 58.3% | 8.36 | 14.33 | 108 | 267 | 2.1 | 4 | 2 | 2 | 18 | 106 | 28 | 0 | 15 | 3 | 197 |
| 16 | A.J. BrownPhiladelphia Eagles·#11 | 13 | 44 | 20 | 284 | 2 | 45.5% | 6.45 | 14.20 | 81 | 510 | 2.6 | 1 | 0 | 0 | 25 | 116 | 40 | 7 | 12 | 0 | 225 |
| 17 | George PickensDallas Cowboys·#3 | 9 | 26 | 15 | 276 | 2 | 57.7% | 10.62 | 18.40 | 116 | 236 | 2.1 | 5 | 2 | 0 | 16 | 89 | 23 | 1 | 12 | 0 | 134 |
| 18 | Rashee RiceKansas City Chiefs·#4 | 5 | 19 | 15 | 153 | 2 | 79.0% | 8.05 | 10.20 | 100 | 54 | 1.0 | 4 | 2 | 2 | 5 | 33 | 14 | 1 | 9 | 0 | 54 |
| 19 | Quentin JohnstonLos Angeles Chargers·#1 | 10 | 30 | 20 | 313 | 2 | 66.7% | 10.43 | 15.65 | 73 | 301 | 2.0 | 3 | 1 | 0 | 15 | 90 | 25 | 0 | 9 | 2 | 175 |
| 20 | Nico CollinsHouston Texans·#12 | 12 | 43 | 28 | 435 | 2 | 65.1% | 10.12 | 15.54 | 151 | 498 | 2.6 | 8 | 5 | 2 | 26 | 121 | 37 | 2 | 19 | 0 | 197 |
| 21 | Tee HigginsCincinnati Bengals·#5 | 9 | 22 | 10 | 166 | 2 | 45.5% | 7.55 | 16.60 | 21 | 236 | 2.5 | 3 | 1 | 0 | 18 | 75 | 18 | 2 | 5 | 0 | 126 |
| 22 | Troy FranklinDenver Broncos·#11 | 14 | 35 | 23 | 220 | 2 | 65.7% | 6.29 | 9.57 | 144 | 249 | 1.8 | 7 | 4 | 1 | 16 | 106 | 19 | 3 | 10 | 0 | 162 |
| 23 | Xavier HutchinsonHouston Texans·#19 | 14 | 30 | 21 | 233 | 2 | 70.0% | 7.77 | 11.10 | 80 | 235 | 1.6 | 4 | 4 | 1 | 19 | 109 | 29 | 1 | 11 | 0 | 167 |
| 24 | Tyquan ThorntonKansas City Chiefs·#80 | 7 | 12 | 8 | 155 | 2 | 66.7% | 12.92 | 19.38 | 23 | 263 | 4.3 | 2 | 2 | 2 | 6 | 39 | 10 | 0 | 7 | 0 | 61 |
| 25 | Tim PatrickJacksonville Jaguars·#17 | 13 | 16 | 12 | 128 | 2 | 75.0% | 8.00 | 10.67 | 34 | 152 | 1.4 | 9 | 6 | 2 | 13 | 66 | 12 | 3 | 7 | 1 | 107 |
| 26 | Michael WilsonArizona Cardinals·#14 | 9 | 17 | 11 | 163 | 2 | 64.7% | 9.59 | 14.82 | 56 | 191 | 1.9 | 2 | 1 | 1 | 14 | 74 | 16 | 3 | 5 | 1 | 122 |
| 27 | Dontayvion WicksGreen Bay Packers·#13 | 10 | 20 | 14 | 180 | 2 | 70.0% | 9.00 | 12.86 | 25 | 264 | 2.3 | 2 | 2 | 1 | 18 | 61 | 19 | 5 | 12 | 1 | 117 |
| 28 | DeVonta SmithPhiladelphia Eagles·#6 | 14 | 50 | 33 | 543 | 2 | 66.0% | 10.86 | 16.45 | 128 | 649 | 2.7 | 2 | 1 | 0 | 27 | 123 | 40 | 9 | 22 | 0 | 251 |
| 29 | Jaylen WaddleMiami Dolphins·#17 | 11 | 38 | 27 | 457 | 2 | 71.0% | 12.03 | 16.93 | 115 | 449 | 3.9 | 5 | 4 | 0 | 16 | 89 | 37 | 3 | 23 | 1 | 139 |
| 30 | Cooper KuppSeattle Seahawks·#10 | 13 | 25 | 17 | 296 | 2 | 68.0% | 11.84 | 17.41 | 170 | 229 | 1.4 | 6 | 4 | 2 | 13 | 111 | 18 | 6 | 13 | 6 | 180 |
| 31 | Chris OlaveNew Orleans Saints·#12 | 5 | 17 | 10 | 154 | 2 | 58.8% | 9.06 | 15.40 | 19 | 188 | 5.7 | 1 | 0 | 0 | 4 | 37 | 17 | 1 | 7 | 0 | 57 |
| 32 | Christian WatsonGreen Bay Packers·#9 | 7 | 22 | 12 | 191 | 2 | 54.5% | 8.68 | 15.92 | 62 | 336 | 3.7 | 2 | 1 | 0 | 19 | 47 | 20 | 4 | 9 | 0 | 100 |
| 33 | Chimere DikeTennessee Titans·#17 | 6 | 14 | 11 | 115 | 2 | 78.6% | 8.21 | 10.45 | 21 | 124 | 1.9 | 3 | 3 | 2 | 11 | 32 | 8 | 4 | 6 | 1 | 67 |
| 34 | Isaac TeSlaaDetroit Lions·#18 | 10 | 9 | 5 | 72 | 2 | 55.6% | 8.00 | 14.40 | 4 | 143 | 1.5 | 3 | 2 | 2 | 6 | 62 | 9 | 1 | 4 | 0 | 95 |
| 35 | Jayden HigginsHouston Texans·#81 | 13 | 27 | 14 | 154 | 2 | 51.9% | 5.70 | 11.00 | 21 | 356 | 2.3 | 2 | 1 | 1 | 19 | 105 | 24 | 1 | 9 | 0 | 156 |
| 36 | Jaylin NoelHouston Texans·#14 | 13 | 16 | 13 | 140 | 2 | 81.3% | 8.75 | 10.77 | 49 | 151 | 1.6 | 1 | 1 | 1 | 9 | 55 | 13 | 0 | 5 | 0 | 92 |
| 37 | Josh DownsIndianapolis Colts·#2 | 12 | 28 | 18 | 143 | 2 | 64.3% | 5.11 | 7.94 | 39 | 171 | 1.5 | 3 | 2 | 2 | 18 | 85 | 26 | 6 | 9 | 1 | 142 |
| 38 | Tory HortonSeattle Seahawks·#15 | 7 | 12 | 6 | 74 | 2 | 50.0% | 6.17 | 12.33 | 9 | 219 | 2.9 | 2 | 1 | 1 | 6 | 53 | 12 | 1 | 2 | 2 | 76 |
| 39 | DeAndre HopkinsBaltimore Ravens·#10 | 13 | 11 | 7 | 130 | 2 | 63.6% | 11.82 | 18.57 | 8 | 203 | 2.8 | 2 | 0 | 0 | 12 | 37 | 10 | 3 | 5 | 1 | 72 |
| 40 | Luther Burden IIIChicago Bears·#10 | 10 | 20 | 15 | 269 | 1 | 75.0% | 13.45 | 17.93 | 140 | 161 | 2.3 | 1 | 1 | 0 | 4 | 48 | 11 | 3 | 7 | 0 | 91 |
| 41 | Mack HollinsNew England Patriots·#13 | 13 | 31 | 22 | 317 | 1 | 71.0% | 10.23 | 14.41 | 76 | 393 | 2.5 | 3 | 2 | 1 | 21 | 100 | 28 | 9 | 16 | 1 | 168 |
| 42 | Marvin Harrison Jr.Arizona Cardinals·#18 | 7 | 20 | 12 | 159 | 1 | 60.0% | 7.95 | 13.25 | 53 | 162 | 1.6 | 4 | 3 | 1 | 11 | 73 | 16 | 3 | 9 | 1 | 112 |
| 43 | Rashod BatemanBaltimore Ravens·#7 | 9 | 15 | 6 | 73 | 1 | 40.0% | 4.87 | 12.17 | 17 | 170 | 1.6 | 6 | 3 | 1 | 8 | 73 | 13 | 3 | 3 | 2 | 108 |
| 44 | Wan'Dale RobinsonNew York Giants·#17 | 9 | 49 | 34 | 428 | 1 | 69.4% | 8.73 | 12.59 | 210 | 288 | 1.9 | 7 | 3 | 0 | 15 | 101 | 37 | 2 | 19 | 1 | 163 |
| 45 | Tre HarrisLos Angeles Chargers·#9 | 12 | 15 | 15 | 137 | 1 | 100.0% | 9.13 | 9.13 | 55 | 82 | 1.0 | 3 | 3 | 1 | 4 | 54 | 12 | 0 | 8 | 1 | 80 |
| 46 | Pat BryantDenver Broncos·#13 | 11 | 14 | 10 | 114 | 1 | 71.4% | 8.14 | 11.40 | 29 | 122 | 1.2 | 1 | 1 | 0 | 9 | 68 | 13 | 2 | 7 | 0 | 100 |
| 47 | CeeDee LambDallas Cowboys·#88 | 7 | 24 | 16 | 280 | 1 | 66.7% | 11.67 | 17.50 | 105 | 295 | 2.6 | 3 | 1 | 0 | 11 | 78 | 21 | 0 | 9 | 0 | 114 |
| 48 | Andrei IosivasCincinnati Bengals·#80 | 10 | 11 | 9 | 130 | 1 | 81.8% | 11.82 | 14.44 | 21 | 124 | 0.9 | 1 | 1 | 0 | 21 | 87 | 10 | 3 | 7 | 0 | 133 |
| 49 | Luke McCaffreyWashington Commanders·#11 | 3 | 4 | 3 | 56 | 1 | 75.0% | 14.00 | 18.67 | 42 | 32 | 1.0 | 1 | 0 | 0 | 1 | 14 | 3 | 0 | 1 | 0 | 32 |
| 50 | Terry McLaurinWashington Commanders·#17 | 5 | 12 | 8 | 173 | 1 | 66.7% | 14.42 | 21.62 | 43 | 207 | 2.4 | 0 | 0 | 0 | 8 | 38 | 12 | 0 | 7 | 2 | 88 |