| 1 | Matthew StaffordLos Angeles Rams·#9 | 17 | 599 | 388 | 64.8% | 4,707 | 7.86 | 46 | 7 | 1.2% | 23 | 5,426 | 9.1 | 2.66 | 2.66 | 29 | 1 | 0 | 19 | 17 | 7 | 1,070 |
| 2 | Jared GoffDetroit Lions·#16 | 17 | 578 | 393 | 68.0% | 4,564 | 7.90 | 34 | 8 | 1.4% | 39 | 3,715 | 6.4 | 2.57 | 2.57 | 19 | 45 | 0 | 8 | 30 | 7 | 1,042 |
| 3 | Drake MayeNew England Patriots·#10 | 17 | 495 | 354 | 71.5% | 4,396 | 8.88 | 31 | 8 | 1.6% | 49 | 4,500 | 9.1 | 2.83 | 2.84 | 104 | 452 | 4 | 18 | 20 | 8 | 1,009 |
| 4 | Dak PrescottDallas Cowboys·#4 | 17 | 599 | 404 | 67.5% | 4,558 | 7.61 | 30 | 9 | 1.5% | 34 | 4,802 | 8.0 | 2.70 | 2.70 | 53 | 177 | 2 | 10 | 15 | 7 | 1,070 |
| 5 | Trevor LawrenceJacksonville Jaguars·#16 | 17 | 562 | 341 | 60.7% | 4,007 | 7.13 | 29 | 12 | 2.1% | 42 | 4,880 | 8.7 | 2.71 | 2.72 | 83 | 361 | 9 | 16 | 13 | 5 | 1,050 |
| 6 | Caleb WilliamsChicago Bears·#18 | 17 | 567 | 330 | 58.2% | 3,944 | 6.96 | 27 | 6 | 1.1% | 28 | 4,904 | 8.5 | 3.05 | 3.05 | 75 | 389 | 3 | 15 | 44 | 4 | 1,098 |
| 7 | Baker MayfieldTampa Bay Buccaneers·#6 | 17 | 543 | 343 | 63.2% | 3,697 | 6.81 | 26 | 11 | 2.0% | 37 | 4,406 | 8.0 | 2.68 | 2.68 | 55 | 382 | 1 | 8 | 13 | 5 | 1,039 |
| 8 | Justin HerbertLos Angeles Chargers·#10 | 16 | 512 | 340 | 66.4% | 3,727 | 7.28 | 26 | 11 | 2.1% | 54 | 4,022 | 7.9 | 2.74 | 2.74 | 84 | 500 | 2 | 15 | 14 | 4 | 995 |
| 9 | Josh AllenBuffalo Bills·#17 | 17 | 460 | 319 | 69.3% | 3,670 | 7.98 | 25 | 10 | 2.2% | 41 | 3,359 | 7.2 | 2.79 | 2.79 | 113 | 579 | 14 | 9 | 15 | 7 | 995 |
| 10 | Jalen HurtsPhiladelphia Eagles·#1 | 16 | 454 | 294 | 64.8% | 3,224 | 7.10 | 25 | 6 | 1.3% | 33 | 4,072 | 8.9 | 2.84 | 2.84 | 107 | 421 | 8 | 10 | 23 | 6 | 927 |
| 11 | Bo NixDenver Broncos·#10 | 17 | 612 | 388 | 63.4% | 3,939 | 6.44 | 25 | 11 | 1.8% | 25 | 4,488 | 7.3 | 2.73 | 2.73 | 82 | 361 | 5 | 17 | 26 | 4 | 1,096 |
| 12 | Sam DarnoldSeattle Seahawks·#14 | 17 | 475 | 323 | 68.0% | 4,052 | 8.53 | 25 | 13 | 2.7% | 28 | 3,740 | 7.8 | 2.73 | 2.74 | 35 | 95 | 0 | 13 | 23 | 9 | 966 |
| 13 | Aaron RodgersPittsburgh Steelers·#8 | 16 | 496 | 327 | 65.9% | 3,324 | 6.70 | 24 | 7 | 1.4% | 31 | 3,018 | 6.0 | 2.48 | 2.48 | 21 | 61 | 1 | 11 | 22 | 4 | 869 |
| 14 | Jacoby BrissettArizona Cardinals·#7 | 14 | 486 | 315 | 64.8% | 3,368 | 6.93 | 23 | 8 | 1.6% | 43 | 3,697 | 7.6 | 2.81 | 2.81 | 38 | 168 | 1 | 7 | 24 | 6 | 771 |
| 15 | Jordan LoveGreen Bay Packers·#10 | 15 | 439 | 291 | 66.3% | 3,385 | 7.71 | 23 | 5 | 1.1% | 21 | 3,863 | 8.8 | 2.73 | 2.73 | 47 | 199 | 0 | 10 | 29 | 4 | 855 |
| 16 | Bryce YoungCarolina Panthers·#9 | 16 | 478 | 304 | 63.6% | 3,013 | 6.30 | 23 | 11 | 2.3% | 28 | 3,102 | 6.4 | 2.68 | 2.68 | 54 | 216 | 2 | 7 | 27 | 8 | 920 |
| 17 | Patrick MahomesKansas City Chiefs·#15 | 14 | 503 | 315 | 62.6% | 3,591 | 7.14 | 22 | 10 | 2.0% | 34 | 4,051 | 8.0 | 2.68 | 2.68 | 64 | 422 | 5 | 17 | 28 | 1 | 889 |
| 18 | Lamar JacksonBaltimore Ravens·#38 | 13 | 304 | 192 | 63.2% | 2,551 | 8.39 | 21 | 7 | 2.3% | 36 | 2,658 | 8.7 | 2.82 | 2.82 | 67 | 349 | 2 | 7 | 13 | 8 | 671 |
| 19 | Tua TagovailoaMiami Dolphins·#1 | 14 | 384 | 260 | 67.7% | 2,662 | 6.93 | 20 | 15 | 3.9% | 31 | 2,608 | 6.7 | 2.52 | 2.52 | 20 | 43 | 0 | 6 | 14 | 3 | 752 |
| 20 | Brock PurdySan Francisco 49ers·#13 | 9 | 285 | 197 | 69.1% | 2,169 | 7.61 | 20 | 10 | 3.5% | 12 | 2,172 | 7.5 | 3.04 | 3.04 | 33 | 147 | 3 | 3 | 17 | 3 | 560 |
| 21 | Daniel JonesIndianapolis Colts·#17 | 13 | 383 | 261 | 68.2% | 3,103 | 8.10 | 19 | 7 | 1.8% | 22 | 3,089 | 7.9 | 2.58 | 2.59 | 46 | 164 | 5 | 8 | 10 | 4 | 718 |
| 22 | C.J. StroudHouston Texans·#7 | 14 | 423 | 273 | 64.5% | 3,041 | 7.19 | 19 | 8 | 1.9% | 24 | 3,398 | 7.9 | 2.70 | 2.70 | 48 | 209 | 1 | 11 | 21 | 2 | 809 |
| 23 | Geno SmithLas Vegas Raiders·#7 | 15 | 447 | 302 | 67.6% | 3,027 | 6.77 | 19 | 17 | 3.8% | 56 | 2,762 | 6.1 | 2.70 | 2.70 | 41 | 109 | 0 | 7 | 11 | 2 | 823 |
| 24 | Joe BurrowCincinnati Bengals·#9 | 8 | 259 | 173 | 66.8% | 1,809 | 6.98 | 17 | 5 | 1.9% | 18 | 1,868 | 7.2 | 2.57 | 2.57 | 14 | 41 | 0 | 12 | 7 | 2 | 460 |
| 25 | Cam WardTennessee Titans·#1 | 17 | 539 | 323 | 59.9% | 3,169 | 5.88 | 15 | 7 | 1.3% | 56 | 3,905 | 7.2 | 2.86 | 2.86 | 39 | 159 | 2 | 12 | 32 | 11 | 956 |
| 26 | Jaxson DartNew York Giants·#6 | 14 | 341 | 216 | 63.3% | 2,274 | 6.67 | 15 | 5 | 1.5% | 36 | 2,783 | 8.1 | 2.69 | 2.69 | 88 | 487 | 9 | 8 | 10 | 5 | 737 |
| 27 | Joe FlaccoCincinnati Bengals·#16 | 10 | 300 | 189 | 63.0% | 1,958 | 6.53 | 14 | 6 | 2.0% | 12 | 2,153 | 7.1 | 2.60 | 2.60 | 17 | 28 | 1 | 7 | 17 | 2 | 470 |
| 28 | Mac JonesSan Francisco 49ers·#10 | 11 | 288 | 201 | 69.8% | 2,153 | 7.48 | 13 | 5 | 1.7% | 18 | 2,119 | 7.3 | 2.54 | 2.54 | 35 | 65 | 0 | 4 | 6 | 3 | 527 |
| 29 | J.J. McCarthyMinnesota Vikings·#9 | 10 | 247 | 140 | 56.7% | 1,634 | 6.62 | 11 | 12 | 4.9% | 27 | 2,142 | 8.6 | 2.81 | 2.81 | 37 | 181 | 4 | 7 | 8 | 2 | 502 |
| 30 | Tyler ShoughNew Orleans Saints·#6 | 11 | 327 | 221 | 67.6% | 2,384 | 7.29 | 10 | 6 | 1.8% | 31 | 2,708 | 8.3 | 2.53 | 2.53 | 45 | 188 | 3 | 9 | 11 | 5 | 582 |
| 31 | Marcus MariotaWashington Commanders·#8 | 11 | 227 | 139 | 61.2% | 1,697 | 7.48 | 10 | 7 | 3.1% | 16 | 2,295 | 10.0 | 2.75 | 2.75 | 50 | 297 | 1 | 3 | 12 | 4 | 486 |
| 32 | Kirk CousinsAtlanta Falcons·#18 | 10 | 269 | 166 | 61.7% | 1,721 | 6.40 | 10 | 5 | 1.9% | 13 | 1,870 | 6.9 | 2.58 | 2.58 | 14 | 7 | 1 | 2 | 12 | 5 | 525 |
| 33 | Michael Penix Jr.Atlanta Falcons·#9 | 9 | 276 | 166 | 60.1% | 1,984 | 7.19 | 9 | 3 | 1.1% | 14 | 2,300 | 8.3 | 2.65 | 2.65 | 21 | 70 | 1 | 4 | 13 | 3 | 525 |
| 34 | Spencer RattlerNew Orleans Saints·#2 | 9 | 256 | 174 | 68.0% | 1,586 | 6.20 | 8 | 4 | 1.6% | 18 | 2,021 | 7.8 | 2.45 | 2.45 | 33 | 167 | 0 | 3 | 7 | 5 | 462 |
| 35 | Jayden DanielsWashington Commanders·#5 | 7 | 189 | 114 | 60.3% | 1,264 | 6.69 | 8 | 2 | 1.1% | 18 | 1,371 | 7.3 | 2.71 | 2.71 | 59 | 278 | 2 | 3 | 11 | 4 | 380 |
| 36 | Dillon GabrielCleveland Browns·#8 | 10 | 184 | 110 | 59.8% | 937 | 5.09 | 7 | 1 | 54.0% | 19 | 1,072 | 5.8 | 2.64 | 2.64 | 14 | 86 | 0 | 1 | 3 | 0 | 352 |
| 37 | Justin FieldsNew York Jets·#7 | 9 | 205 | 128 | 62.4% | 1,254 | 6.12 | 7 | 1 | 49.0% | 27 | 1,389 | 6.6 | 2.76 | 2.78 | 73 | 387 | 4 | 2 | 8 | 5 | 486 |
| 38 | Shedeur SandersCleveland Browns·#12 | 8 | 211 | 120 | 56.9% | 1,400 | 6.64 | 7 | 9 | 4.3% | 23 | 1,519 | 7.2 | 3.10 | 3.10 | 22 | 169 | 1 | 2 | 15 | 3 | 413 |
| 39 | Kyler MurrayArizona Cardinals·#1 | 5 | 164 | 110 | 67.1% | 962 | 5.87 | 6 | 3 | 1.8% | 16 | 941 | 5.8 | 2.56 | 2.56 | 29 | 173 | 1 | 2 | 5 | 3 | 299 |
| 40 | Jake BrowningCincinnati Bengals·#6 | 5 | 126 | 81 | 64.3% | 771 | 6.12 | 6 | 8 | 6.3% | 9 | 959 | 7.7 | 2.62 | 2.62 | 10 | 39 | 1 | 1 | 6 | 3 | 198 |
| 41 | Carson WentzMinnesota Vikings·#11 | 5 | 169 | 110 | 65.1% | 1,218 | 7.21 | 6 | 5 | 3.0% | 21 | 1,288 | 7.6 | 2.60 | 2.60 | 11 | 57 | 0 | 2 | 5 | 2 | 286 |
| 42 | Tyrod TaylorNew York Jets·#2 | 6 | 136 | 80 | 58.8% | 779 | 5.73 | 5 | 5 | 3.7% | 14 | 1,145 | 8.5 | 2.87 | 2.87 | 27 | 143 | 1 | 1 | 5 | 2 | 239 |
| 43 | Davis MillsHouston Texans·#10 | 6 | 159 | 91 | 57.2% | 917 | 5.77 | 5 | 1 | 63.0% | 8 | 1,360 | 8.4 | 2.46 | 2.46 | 14 | 60 | 1 | 2 | 10 | 0 | 282 |
| 44 | Philip RiversIndianapolis Colts·#17 | 3 | 92 | 58 | 63.0% | 544 | 5.91 | 4 | 3 | 3.3% | 5 | 717 | 7.8 | 2.30 | 2.30 | 2 | -1 | 0 | 3 | 2 | 0 | 166 |
| 45 | Mitchell TrubiskyBuffalo Bills·#11 | 4 | 35 | 25 | 71.4% | 315 | 9.00 | 4 | 0 | 0.0% | 0 | 255 | 6.9 | 2.71 | 2.71 | 9 | 6 | 0 | 0 | 1 | 0 | 96 |
| 46 | Malik WillisGreen Bay Packers·#2 | 4 | 36 | 30 | 83.3% | 422 | 11.72 | 3 | 0 | 0.0% | 3 | 354 | 10.1 | 2.53 | 2.53 | 22 | 123 | 2 | 2 | 0 | 2 | 95 |
| 47 | Russell WilsonNew York Giants·#3 | 6 | 119 | 69 | 58.0% | 831 | 6.98 | 3 | 3 | 2.5% | 10 | 1,058 | 8.9 | 2.53 | 2.53 | 18 | 106 | 0 | 2 | 12 | 0 | 191 |
| 48 | Quinn EwersMiami Dolphins·#14 | 4 | 83 | 55 | 66.3% | 622 | 7.49 | 3 | 3 | 3.6% | 8 | 683 | 8.3 | 2.60 | 2.60 | 8 | 19 | 0 | 2 | 0 | 2 | 175 |
| 49 | Tyler HuntleyBaltimore Ravens·#5 | 5 | 68 | 52 | 76.5% | 426 | 6.26 | 2 | 0 | 0.0% | 8 | 429 | 6.4 | 2.32 | 2.32 | 25 | 151 | 0 | 0 | 1 | 1 | 190 |
| 50 | Riley LeonardIndianapolis Colts·#15 | 5 | 67 | 39 | 58.2% | 415 | 6.19 | 2 | 3 | 4.5% | 2 | 537 | 7.9 | 2.70 | 2.70 | 7 | 27 | 2 | 0 | 3 | 3 | 125 |