| 1 | Matthew StaffordLos Angeles Rams·#9 | 17 | 110 | 69 | 62.7% | 429 | 3.90 | 33 | 2 | 1.8% | 3 | 353 | 3.2 | 2.36 | 2.36 | 7 | -3 | 0 | 4 | 1 | 2 | 203 |
| 2 | Jared GoffDetroit Lions·#16 | 17 | 94 | 53 | 56.4% | 420 | 4.47 | 25 | 2 | 2.1% | 5 | 400 | 4.3 | 2.49 | 2.48 | 3 | 0 | 0 | 0 | 2 | 0 | 191 |
| 3 | Jacoby BrissettArizona Cardinals·#7 | 12 | 85 | 49 | 57.6% | 386 | 4.54 | 19 | 2 | 2.4% | 9 | 621 | 7.1 | 2.79 | 2.79 | 5 | 3 | 1 | 2 | 4 | 1 | 128 |
| 4 | Bo NixDenver Broncos·#10 | 17 | 87 | 53 | 60.9% | 370 | 4.25 | 17 | 1 | 1.1% | 3 | 298 | 3.2 | 2.56 | 2.57 | 17 | 65 | 5 | 4 | 3 | 0 | 171 |
| 5 | Dak PrescottDallas Cowboys·#4 | 17 | 103 | 57 | 55.3% | 352 | 3.42 | 21 | 3 | 2.9% | 6 | 554 | 5.3 | 2.57 | 2.57 | 12 | 17 | 2 | 4 | 5 | 0 | 194 |
| 6 | Trevor LawrenceJacksonville Jaguars·#16 | 16 | 88 | 51 | 58.0% | 331 | 3.76 | 23 | 4 | 4.5% | 2 | 424 | 4.6 | 2.64 | 2.63 | 24 | 87 | 9 | 1 | 4 | 2 | 198 |
| 7 | Drake MayeNew England Patriots·#10 | 17 | 72 | 47 | 65.3% | 327 | 4.54 | 20 | 3 | 4.2% | 10 | 324 | 4.4 | 2.63 | 2.63 | 22 | 71 | 4 | 1 | 7 | 2 | 179 |
| 8 | Aaron RodgersPittsburgh Steelers·#8 | 16 | 77 | 47 | 61.0% | 311 | 4.04 | 14 | 1 | 1.3% | 2 | 301 | 3.8 | 2.34 | 2.34 | 3 | 4 | 1 | 1 | 6 | 1 | 143 |
| 9 | Justin HerbertLos Angeles Chargers·#10 | 16 | 83 | 43 | 51.8% | 295 | 3.55 | 20 | 4 | 4.8% | 7 | 413 | 5.0 | 3.01 | 3.01 | 14 | 33 | 2 | 3 | 4 | 0 | 165 |
| 10 | Jordan LoveGreen Bay Packers·#10 | 15 | 64 | 39 | 60.9% | 295 | 4.61 | 17 | 0 | 0.0% | 1 | 293 | 4.4 | 2.76 | 2.76 | 6 | 25 | 0 | 2 | 8 | 1 | 143 |
| 11 | Baker MayfieldTampa Bay Buccaneers·#6 | 17 | 67 | 40 | 59.7% | 292 | 4.36 | 16 | 1 | 1.5% | 4 | 391 | 5.4 | 2.72 | 2.72 | 9 | 16 | 1 | 2 | 2 | 0 | 146 |
| 12 | Patrick MahomesKansas City Chiefs·#15 | 14 | 87 | 46 | 52.9% | 288 | 3.31 | 18 | 3 | 3.5% | 3 | 306 | 3.4 | 2.41 | 2.41 | 15 | 98 | 5 | 3 | 12 | 1 | 167 |
| 13 | Josh AllenBuffalo Bills·#17 | 16 | 65 | 42 | 64.6% | 281 | 4.32 | 16 | 3 | 4.6% | 5 | 245 | 3.4 | 2.94 | 2.94 | 33 | 80 | 13 | 2 | 3 | 0 | 182 |
| 14 | Sam DarnoldSeattle Seahawks·#14 | 17 | 67 | 39 | 58.2% | 270 | 4.03 | 15 | 2 | 3.0% | 4 | 394 | 5.7 | 2.80 | 2.80 | 6 | 4 | 0 | 2 | 5 | 1 | 170 |
| 15 | Bryce YoungCarolina Panthers·#9 | 16 | 68 | 40 | 58.8% | 244 | 3.59 | 14 | 2 | 2.9% | 5 | 335 | 4.7 | 2.67 | 2.67 | 11 | 34 | 2 | 2 | 4 | 2 | 140 |
| 16 | Tua TagovailoaMiami Dolphins·#1 | 14 | 55 | 36 | 65.5% | 242 | 4.40 | 16 | 0 | 0.0% | 4 | 186 | 3.2 | 2.49 | 2.49 | 2 | 6 | 0 | 3 | 2 | 1 | 118 |
| 17 | Jalen HurtsPhiladelphia Eagles·#1 | 16 | 51 | 37 | 72.5% | 233 | 4.57 | 16 | 2 | 3.9% | 3 | 237 | 4.4 | 2.18 | 2.18 | 27 | 69 | 8 | 0 | 0 | 1 | 132 |
| 18 | Daniel JonesIndianapolis Colts·#17 | 13 | 57 | 34 | 59.6% | 228 | 4.00 | 16 | 0 | 0.0% | 4 | 244 | 3.8 | 2.47 | 2.50 | 16 | 30 | 5 | 1 | 4 | 0 | 146 |
| 19 | Geno SmithLas Vegas Raiders·#7 | 14 | 58 | 35 | 60.3% | 217 | 3.74 | 15 | 3 | 5.2% | 6 | 309 | 5.2 | 2.74 | 2.74 | 7 | 21 | 0 | 2 | 1 | 0 | 109 |
| 20 | Brock PurdySan Francisco 49ers·#13 | 9 | 56 | 33 | 58.9% | 215 | 3.84 | 16 | 1 | 1.8% | 2 | 294 | 4.8 | 3.45 | 3.43 | 7 | 37 | 3 | 1 | 7 | 0 | 124 |
| 21 | Mac JonesSan Francisco 49ers·#10 | 8 | 39 | 30 | 76.9% | 200 | 5.13 | 12 | 0 | 0.0% | 2 | 181 | 4.4 | 2.57 | 2.57 | 3 | 4 | 0 | 1 | 0 | 0 | 80 |
| 22 | Caleb WilliamsChicago Bears·#18 | 17 | 73 | 39 | 53.4% | 195 | 2.67 | 14 | 2 | 2.7% | 7 | 313 | 4.0 | 2.91 | 2.93 | 19 | 68 | 3 | 2 | 6 | 0 | 183 |
| 23 | Cam WardTennessee Titans·#1 | 15 | 54 | 36 | 66.7% | 188 | 3.48 | 12 | 2 | 3.7% | 5 | 203 | 3.8 | 2.92 | 2.92 | 10 | 20 | 2 | 1 | 3 | 1 | 103 |
| 24 | Jaxson DartNew York Giants·#6 | 13 | 47 | 20 | 42.5% | 177 | 3.77 | 9 | 0 | 0.0% | 7 | 329 | 6.5 | 3.02 | 3.04 | 22 | 86 | 8 | 3 | 4 | 1 | 120 |
| 25 | Joe BurrowCincinnati Bengals·#9 | 8 | 42 | 22 | 52.4% | 172 | 4.10 | 14 | 2 | 4.8% | 1 | 226 | 5.1 | 2.38 | 2.38 | 2 | 4 | 0 | 5 | 1 | 1 | 81 |
| 26 | Joe FlaccoCincinnati Bengals·#16 | 7 | 37 | 19 | 51.4% | 161 | 4.35 | 9 | 1 | 2.7% | 3 | 212 | 5.4 | 2.49 | 2.49 | 5 | -8 | 1 | 2 | 4 | 0 | 66 |
| 27 | C.J. StroudHouston Texans·#7 | 14 | 54 | 30 | 55.6% | 160 | 2.96 | 12 | 0 | 0.0% | 5 | 230 | 4.0 | 2.97 | 2.97 | 8 | 12 | 1 | 1 | 5 | 0 | 112 |
| 28 | J.J. McCarthyMinnesota Vikings·#9 | 10 | 37 | 16 | 43.2% | 151 | 4.08 | 10 | 0 | 0.0% | 6 | 218 | 5.7 | 2.67 | 2.67 | 6 | 45 | 4 | 2 | 2 | 0 | 76 |
| 29 | Kirk CousinsAtlanta Falcons·#18 | 8 | 33 | 18 | 54.5% | 149 | 4.52 | 9 | 1 | 3.0% | 2 | 187 | 5.3 | 2.54 | 2.54 | 1 | 1 | 1 | 0 | 2 | 2 | 67 |
| 30 | Lamar JacksonBaltimore Ravens·#38 | 12 | 44 | 19 | 43.2% | 135 | 3.07 | 11 | 2 | 4.5% | 7 | 239 | 5.0 | 3.00 | 3.00 | 13 | 53 | 2 | 1 | 6 | 0 | 114 |
| 31 | Carson WentzMinnesota Vikings·#11 | 5 | 34 | 18 | 52.9% | 130 | 3.82 | 6 | 0 | 0.0% | 5 | 222 | 6.3 | 2.52 | 2.52 | 2 | 3 | 0 | 0 | 1 | 0 | 54 |
| 32 | Tyler ShoughNew Orleans Saints·#6 | 10 | 21 | 13 | 61.9% | 129 | 6.14 | 7 | 1 | 4.8% | 6 | 182 | 8.3 | 2.35 | 2.37 | 14 | 32 | 2 | 5 | 2 | 0 | 64 |
| 33 | Michael Penix Jr.Atlanta Falcons·#9 | 8 | 30 | 16 | 53.3% | 111 | 3.70 | 8 | 0 | 0.0% | 2 | 158 | 5.1 | 2.51 | 2.51 | 3 | 10 | 1 | 2 | 0 | 0 | 75 |
| 34 | Spencer RattlerNew Orleans Saints·#2 | 7 | 32 | 16 | 50.0% | 99 | 3.09 | 6 | 0 | 0.0% | 0 | 244 | 7.4 | 2.39 | 2.40 | 5 | 31 | 0 | 2 | 2 | 0 | 58 |
| 35 | Justin FieldsNew York Jets·#7 | 7 | 23 | 12 | 52.2% | 95 | 4.13 | 3 | 0 | 0.0% | 3 | 125 | 4.3 | 2.85 | 2.93 | 13 | 39 | 3 | 1 | 2 | 1 | 69 |
| 36 | Davis MillsHouston Texans·#10 | 4 | 25 | 12 | 48.0% | 94 | 3.76 | 5 | 0 | 0.0% | 3 | 190 | 7.0 | 2.52 | 2.52 | 3 | 14 | 1 | 0 | 2 | 0 | 52 |
| 37 | Dillon GabrielCleveland Browns·#8 | 8 | 32 | 15 | 46.9% | 94 | 2.94 | 6 | 0 | 0.0% | 2 | 152 | 4.6 | 2.49 | 2.49 | 2 | 8 | 0 | 1 | 1 | 0 | 55 |
| 38 | Jayden DanielsWashington Commanders·#5 | 7 | 22 | 11 | 50.0% | 93 | 4.23 | 6 | 1 | 4.5% | 3 | 83 | 3.6 | 2.87 | 2.90 | 7 | 26 | 2 | 1 | 4 | 0 | 53 |
| 39 | Marcus MariotaWashington Commanders·#8 | 10 | 30 | 14 | 46.7% | 92 | 3.07 | 7 | 2 | 6.7% | 0 | 167 | 5.1 | 2.60 | 2.60 | 8 | 18 | 1 | 0 | 2 | 0 | 79 |
| 40 | Kyler MurrayArizona Cardinals·#1 | 5 | 20 | 13 | 65.0% | 78 | 3.90 | 6 | 1 | 5.0% | 1 | 45 | 2.3 | 2.50 | 2.50 | 4 | 13 | 1 | 1 | 1 | 1 | 39 |
| 41 | Tyrod TaylorNew York Jets·#2 | 5 | 15 | 7 | 46.7% | 49 | 3.27 | 4 | 0 | 0.0% | 0 | 104 | 6.9 | 2.43 | 2.43 | 3 | 13 | 1 | 0 | 0 | 1 | 26 |
| 42 | Tyler HuntleyBaltimore Ravens·#5 | 4 | 14 | 8 | 57.1% | 46 | 3.29 | 2 | 0 | 0.0% | 3 | 80 | 6.2 | 2.68 | 2.68 | 7 | 25 | 0 | 0 | 1 | 0 | 49 |
| 43 | Shedeur SandersCleveland Browns·#12 | 7 | 14 | 9 | 64.3% | 45 | 3.21 | 3 | 0 | 0.0% | 3 | 10 | 0.7 | 3.04 | 3.04 | 2 | 7 | 1 | 0 | 2 | 0 | 35 |
| 44 | Riley LeonardIndianapolis Colts·#15 | 2 | 16 | 7 | 43.8% | 42 | 2.62 | 1 | 0 | 0.0% | 0 | 95 | 5.6 | 2.48 | 2.48 | 2 | 7 | 2 | 0 | 1 | 0 | 25 |
| 45 | Quinn EwersMiami Dolphins·#14 | 3 | 11 | 7 | 63.6% | 34 | 3.09 | 2 | 1 | 9.1% | 0 | 34 | 4.0 | 2.82 | 2.82 | 0 | 0 | 0 | 1 | 0 | 0 | 25 |
| 46 | Brady CookNew York Jets·#4 | 5 | 19 | 6 | 31.6% | 23 | 1.21 | 2 | 3 | 15.8% | 0 | 52 | 2.6 | 2.16 | 2.16 | 0 | 0 | 0 | 0 | 0 | 0 | 35 |
| 47 | Russell WilsonNew York Giants·#3 | 4 | 20 | 4 | 20.0% | 16 | 0.80 | 0 | 0 | 0.0% | 0 | 109 | 5.5 | 2.78 | 2.78 | 7 | 21 | 0 | 0 | 6 | 0 | 36 |
| 48 | Jameis WinstonNew York Giants·#19 | 3 | 9 | 2 | 22.2% | 15 | 1.67 | 1 | 1 | 11.1% | 1 | 66 | 7.3 | 2.84 | 2.84 | 2 | 3 | 1 | 0 | 3 | 0 | 29 |
| 49 | Josh JohnsonWashington Commanders·#14 | 3 | 5 | 2 | 40.0% | 8 | 1.60 | 1 | 0 | 0.0% | 1 | 17 | 3.4 | 2.64 | 2.64 | 2 | 8 | 1 | 0 | 1 | 0 | 27 |